3,235 research outputs found
Efficient Privacy Preserving Viola-Jones Type Object Detection via Random Base Image Representation
A cloud server spent a lot of time, energy and money to train a Viola-Jones
type object detector with high accuracy. Clients can upload their photos to the
cloud server to find objects. However, the client does not want the leakage of
the content of his/her photos. In the meanwhile, the cloud server is also
reluctant to leak any parameters of the trained object detectors. 10 years ago,
Avidan & Butman introduced Blind Vision, which is a method for securely
evaluating a Viola-Jones type object detector. Blind Vision uses standard
cryptographic tools and is painfully slow to compute, taking a couple of hours
to scan a single image. The purpose of this work is to explore an efficient
method that can speed up the process. We propose the Random Base Image (RBI)
Representation. The original image is divided into random base images. Only the
base images are submitted randomly to the cloud server. Thus, the content of
the image can not be leaked. In the meanwhile, a random vector and the secure
Millionaire protocol are leveraged to protect the parameters of the trained
object detector. The RBI makes the integral-image enable again for the great
acceleration. The experimental results reveal that our method can retain the
detection accuracy of that of the plain vision algorithm and is significantly
faster than the traditional blind vision, with only a very low probability of
the information leakage theoretically.Comment: 6 pages, 3 figures, To appear in the proceedings of the IEEE
International Conference on Multimedia and Expo (ICME), Jul 10, 2017 - Jul
14, 2017, Hong Kong, Hong Kon
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Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression.
For antibody discovery and engineering, yeast surface display (YSD) of antigen-binding fragments (Fabs) and coupled fluorescence activated cell sorting (FACS) provide intact paratopic conformations and quantitative analysis at the monoclonal level, and thus holding great promises for numerous applications. Using anti-TNFα mAbs Infliximab, Adalimumab, and its variants as model Fabs, this study systematically characterized complementary approaches for the optimization of Fab YSD. Results suggested that by using divergent promoter GAL1-GAL10 and endoplasmic reticulum (ER) signal peptides for co-expression of light chain and heavy chain-Aga2 fusion, assembled Fabs were functionally displayed on yeast cell surface with sigmoidal binding responses toward TNFα. Co-expression of a Hsp70 family molecular chaperone Kar2p and/or protein-disulfide isomerase (Pdi1p) significantly improved efficiency of functional display (defined as the ratio of cells displaying functional Fab over cells displaying assembled Fab). Moreover, fusing ER retention sequences (ERSs) with light chain also enhanced Fab display quality at the expense of display quantity, and the degree of improvements was correlated with the strength of ERSs and was more significant for Infliximab than Adalimumab. The feasibility of affinity maturation was further demonstrated by isolating a high affinity Fab clone from 1:103 or 1:105 spiked libraries
The juxtamembrane and carboxy-terminal domains of Arabidopsis PRK2 are critical for ROP-induced growth in pollen tubes.
Polarized growth of pollen tubes is a critical step for successful reproduction in angiosperms and is controlled by ROP GTPases. Spatiotemporal activation of ROP (Rho GTPases of plants) necessitates a complex and sophisticated regulatory system, in which guanine nucleotide exchange factors (RopGEFs) are key components. It was previously shown that a leucine-rich repeat receptor-like kinase, Arabidopsis pollen receptor kinase 2 (AtPRK2), interacted with RopGEF12 for its membrane recruitment. However, the mechanisms underlying AtPRK2-mediated ROP activation in vivo are yet to be defined. It is reported here that over-expression of AtPRK2 induced tube bulging that was accompanied by the ectopic localization of ROP-GTP and the ectopic distribution of actin microfilaments. Tube depolarization was also induced by a potentially kinase-dead mutant, AtPRK2K366R, suggesting that the over-expression effect of AtPRK2 did not require its kinase activity. By contrast, deletions of non-catalytic domains in AtPRK2, i.e. the juxtamembrane (JM) and carboxy-terminal (CT) domains, abolished its ability to affect tube polarization. Notably, AtPRK2K366R retained the ability to interact with RopGEF12, whereas AtPRK2 truncations of these non-catalytic domains did not. Lastly, it has been shown that the JM and CT domains of AtPRK2 were not only critical for its interaction with RopGEF12 but also critical for its distribution at the plasma membrane. These results thus provide further insight into pollen receptor kinase-mediated ROP activation during pollen tube growth
Predicting Aesthetic Score Distribution through Cumulative Jensen-Shannon Divergence
Aesthetic quality prediction is a challenging task in the computer vision
community because of the complex interplay with semantic contents and
photographic technologies. Recent studies on the powerful deep learning based
aesthetic quality assessment usually use a binary high-low label or a numerical
score to represent the aesthetic quality. However the scalar representation
cannot describe well the underlying varieties of the human perception of
aesthetics. In this work, we propose to predict the aesthetic score
distribution (i.e., a score distribution vector of the ordinal basic human
ratings) using Deep Convolutional Neural Network (DCNN). Conventional DCNNs
which aim to minimize the difference between the predicted scalar numbers or
vectors and the ground truth cannot be directly used for the ordinal basic
rating distribution. Thus, a novel CNN based on the Cumulative distribution
with Jensen-Shannon divergence (CJS-CNN) is presented to predict the aesthetic
score distribution of human ratings, with a new reliability-sensitive learning
method based on the kurtosis of the score distribution, which eliminates the
requirement of the original full data of human ratings (without normalization).
Experimental results on large scale aesthetic dataset demonstrate the
effectiveness of our introduced CJS-CNN in this task.Comment: AAAI Conference on Artificial Intelligence (AAAI), New Orleans,
Louisiana, USA. 2-7 Feb. 201
Code Generation as a Dual Task of Code Summarization
Code summarization (CS) and code generation (CG) are two crucial tasks in the
field of automatic software development. Various neural network-based
approaches are proposed to solve these two tasks separately. However, there
exists a specific intuitive correlation between CS and CG, which have not been
exploited in previous work. In this paper, we apply the relations between two
tasks to improve the performance of both tasks. In other words, exploiting the
duality between the two tasks, we propose a dual training framework to train
the two tasks simultaneously. In this framework, we consider the dualities on
probability and attention weights, and design corresponding regularization
terms to constrain the duality. We evaluate our approach on two datasets
collected from GitHub, and experimental results show that our dual framework
can improve the performance of CS and CG tasks over baselines.Comment: To appear at the 33rd Conference on Neural Information Processing
Systems (NeurIPS) 201
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