76 research outputs found
Multicentric chemodectomata at high altitude
Multicentric chemodectomata in the right glomus intravagale and both carotid bodies were excised from a 74 year-old woman. These are rare tumours. The patient was born and lived at an altitude of 1 800 m above sea level. The effects of altitude and chronic hypoxia on the carotid bodies are discussed. Some chemodectomata may, in fact, be extreme examples 'of hypoxia - induced hyperplasia of chemoreceptor tissue.S. Afr. Med. J., 48, 1715. (1974
WARM KNEES AND COLD FEET
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/33437/1/0000839.pd
Safety of Infusing Rituximab at a More Rapid Rate in Patients with Rheumatoid Arthritis: Results from the RATE-RA Study
As recommended in the current prescribing information, rituximab infusions in patients with rheumatoid arthritis (RA) take 4.25hours for the first infusion and 3.25hours for subsequent infusions, which is a burden on patients and the health care system. We therefore evaluated the safety of infusing rituximab at a faster rate for an infusion period of 2hours in patients with RA
Retreatment with rituximab based on a treatment-to-target approach provides better disease control than treatment as needed in patients with rheumatoid arthritis: a retrospective pooled analysis
Objective. To assess the efficacy and safety profiles of two different rituximab retreatment regimens in patients with RA
Popliteal Arterial Aneurysms
Fifty-five popliteal aneurysms in 43 patients seen over a 15-year period, are presented. The commonest cause was atherosclerosis, with a male incidence of 98%. Bilateral popliteal aneurysms were found in 29% of this group. and extrapopliteal in 11% of patients. Sixty-seven per cent of the patients had complications when they were first seen, and the commonest complication was acute arterial occlusion caused by thromboembolism. The reasons for the high incidence of thromboembolism are discussed. Rupture was uncommon. Small aneurysms are not immune to complications and in the absence of contra-indicating factors such as short life expectancy, or poor surgical risk, all popliteal aneurysms should be considered for reconstructive vascular procedures
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