A prospective randomized controlled study comparing short-term outcomes of closure and non-closure of peritoneum during elective caesarean section

Background: There is a rising trend of caesarean deliveries worldwide. Although a very commonly performed abdominal surgery, there is no ideal operative procedure in the literature. Several studies compared short term and long-term outcomes of closure and non-closure of peritoneum, but there is no consensus whether either procedure is beneficial to patients. Variability of results may be due to bias involved in these studies as two groups compared had different characteristics (including obstetrics and non-obstetrics laparotomies, elective and emergency caesareans, Pfannenstiel as well as vertical incisions; in the same study) which are likely to affect short term outcomes besides those due to peritoneal closer and non-closure. Aims and objectives of the study were to perform an unbiased assessment of short-term outcomes in elective LSCS in unscarred abdomens by Pfannenstiel incisions between closure (CG) and non-closure of peritoneum (NCG).Methods: Prospective randomised controlled study method used in the study.Results: The operating time was significantly more (p=0.01) with difference of additional 10 minutes in CG with standard error of mean for time being 3.7688. Pain score was more in CG on post-operative day 1 and 2 (p=0.0003 and 0.008 respectively). Additional anaesthesia and analgesia were not needed in this group.Conclusions: Apart from operative timing and pain score in early post-op period, there was no significant difference in short term outcomes between CG and NCG during elective caesarean section. Hence only long-term effects of these procedures need to be considered prior to recommending ideal steps of elective caesarean section procedure

N-Square Approach For Lossless Image Compression And Decompression

There are several lossy and lossless coding techniques developed all through the last two decades. Although very high compression can be achieved with lossy compression techniques, they are deficient in obtaining the original image. While lossless compression technique recovers the image exactly. In applications related to medical imaging lossless techniques are required, as the loss of information is deplorable. The objective of image compression is to symbolize an image with a handful number of bits as possible while preserving the quality required for the given application. In this paper we are introducing a new lossless encoding and decoding technique which even better reduces the entropy there by reducing the average number of bits with the utility of Non Binary Huffman coding through the use of N-Square approach and fasten the process of searching for a codeword in a N-Square tree, we exploit the property of the encoded image pixels, and propose a memory efficient data structure to represent a decoding N-Square tree. Our extensive experimental results demonstrate that the proposed scheme is very competitive and this addresses the limitations of D value in the existing system by proposing a pattern called N-Square approach for it. The newly proposed algorithm provides a good means for lossless image compression and decompression

Asymptotic and near-target direct breakup of ⁶Li and ⁷Li

Background: Li6,7 and Be9 are weakly bound against breakup into their cluster constituents. Breakup location is important for determining the role of breakup in above-barrier complete fusion suppression. Recent works have pointed out that experimental observables can be used to separate near-target and asymptotic breakup. Purpose: Our purpose is to distinguish near-target and asymptotic direct breakup of Li6,7 in reactions with nuclei in different mass regions. Method: Charged particle coincidence measurements are carried out with pulsed Li6,7 beams on Ni58 and Zn64 targets at sub-barrier energies and compared with previous measurements using Pb208 and Bi209 targets. A detector array providing a large angular coverage is used, along with time-of-flight information to give definitive particle identification of the direct breakup fragments. Results: In interactions of Li6 with Ni58 and Zn64, direct breakup occurs only asymptotically far away from the target. However, in interactions with Pb208 and Bi209, near-target breakup occurs in addition to asymptotic breakup. Direct breakup of Li7 into α−t is not observed in interactions with Ni58 and Zn64. However, near-target dominated direct breakup was observed in measurements with Pb208 and Bi209. A modified version of the Monte Carlo classical trajectory model code platypus, which explicitly takes into account lifetimes associated with unbound states, is used to simulate sub-barrier breakup reaction

Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

<p>Abstract</p> <p>Background</p> <p>Cancer progression is linked to a partially dedifferentiated epithelial cell phenotype. The signaling pathways Wnt, Hedgehog, TGF-β and Notch have been implicated in experimental and developmental epithelial mesenchymal transition (EMT). Recent findings from our laboratory confirm that active Wnt/β-catenin signaling is critically involved in invasive ductal carcinomas (IDCs) of breast.</p> <p>Methods</p> <p>In the current study, we analyzed the expression patterns and relationships between the key Wnt/β-catenin signaling components- E-cadherin, Slug and GSK3β in IDCs of breast.</p> <p>Results</p> <p>Of the 98 IDCs analyzed, 53 (54%) showed loss/or reduced membranous staining of E-cadherin in tumor cells. Nuclear accumulation of Slug was observed in 33 (34%) IDCs examined. Loss or reduced level of cytoplasmic GSK3β expression was observed in 52/98 (53%) cases; while 34/98 (35%) tumors showed nuclear accumulation of GSK3β. Statistical analysis revealed associations of nuclear Slug expression with loss of membranous E-cadherin (p = 0.001); nuclear β-catenin (p = 0.001), and cytoplasmic β-catenin (p = 0.005), suggesting Slug mediated E-cadherin suppression via the activation of Wnt/β-catenin signaling pathway in IDCs. Our study also demonstrated significant correlation between GSK3β nuclear localization and tumor grade (p = 0.02), suggesting its association with tumor progression.</p> <p>Conclusion</p> <p>The present study for the first time provided the clinical evidence in support of Wnt/β-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3β with β-catenin in implementing EMT in these cells.</p

<span style="font-size:14.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; color:black;mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language: HI" lang="EN-IN">Identification of a 75 kDa highly immunodominant antigen from <i>Mycobacterium smegmatis </i>and cross-reactivity with other species</span>

255-262Three monospecific antibodies MSAb 1, MSAb 2 and MSAb 3 were raised in BALB/C mice against respective antigens. M. smegmatis whole cell lysate was first separated on SDS-PAGE and randomly chosen bands were cut and then used for immunization. Antibodies were collected as ascites by injecting mice with myeloma cell line P3X63 Ag 658.4. All the three antibodies showed high reactivity with denatured antigens compared to native. Different extent of cross-reactivity was observed as evident from ELISA. MSAb 1 recognized a 75 kDa immunodominant antigen from M. smegmatis and 66 kDa from M. tuberculosis (H37Ra), respectively. An apparently similar molecular weight antigen shown to be present in M. tuberculosis (H37Ra) an avirulent strain and BCG, but not recognized by MSAb1. The 75 kDa antigen has a stimulatory effect on T-cell proliferation.</span

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Not AvailableField trials were conducted for management of the wilt disease in castor during 2016-17 and 2017-18. Soil solarisation during summer followed by seed treatment and soil application of carbendazim as well as soil solarisation along with seed treatment and soil application of Trichoderma harzianum were effective in reduction of wilt disease. Pathogen population had also decreased in soil samples collected at the time of harvest in plots with solarization, neem cake, and Trichoderma applied treatments.Not Availabl

Isolation, Identification, and Pathogenicity of a Virulent Aeromonas jandaei Associated with Mortality of Farmed Pangasianodon hypophthalmus, in India

The present study was conducted to investigate the bacterial pathogens involved in the mortality of cultured Pangasianodon hypophthalmus. Diseased fish samples were collected from Maharashtra, India for the isolation of pathogenic bacteria. The pathogenic bacterial isolates were identified using 16S rRNA gene sequencing analysis which revealed that they were 99% identical with Aeromonas jandaei. The bacterial isolates were further characterized using biochemical methods. The lowest bacterial dose which caused 50% cumulative mortality (LD50) in Pangasianodon hypophthalmus was 8.84 X 105 CFU per fish. This was achieved by injecting the fish intraperitoneally with pure culture of A.jandaei isolated from diseased fish. Histopathogical studies revealed necrosis hemorrhaging, and other cellular alterations of different tissues of collected organs viz. gill, liver, and kidney of P. hypophthalmus, observed with the diseased conditions

Regional differences in androgen thresholds of the epididymis of the castrated rat

The action of graded doses of testosterone and dihydrotestosterone on the maintenance of the functional integrity of the different regions of the epididymis of the castrated rat was investigated. The epididymis required higher amounts of androgens that the accessory glanss for maintenance of its weight and secretory activity. These results are discussed in relation to (a) the androgen differences in the epididymis in its response to androgens and (c) the mode of action of the two androgens

Assessment of Unmet Need for Contraception among eligible couples in Urban Slums of Raipur city of Chhattisgarh state

Background: India was the first country to launch National Family Planning Program in 1952. Even though various measures have been taken to encourage the usage of contraception but the achievement in this field was not to the extent expected due to various social and cultural factors. Objective: This study was planned to assess the prevalence and its determinants of unmet need for contraception among eligible couples in urban slums of Raipur city. Methodology: A cross sectional community based study was conducted using cluster sampling in urban slums of Raipur city from November 2011 to October 2012. During the study, 711 fecund married women, age group 15-49 years were included and predesigned and pretested proforma was used as a study tool. The obtained data were analyzed using appropriate statistical test. Results: Among all eligible married women 45 % were concentrated in the prime reproductive age 20-29 yrs. Majority of women were not educated. The total unmet need for family planning comes out to 32.9%. Age, Education, literacy, Occupation, Type of Family, No of living children, Birth Order , No of male child, No of female child , Husband literacy were the most significant predictor of unmet need. Conclusion: Percentage of unmet need is higher as compared to national data, so there is urgently need to ensure the same

Effect of antiserum to luteinizing hormone (LHAS) on the physiology of the epididymis and accessory glands in the albino rat

Rabbit antiserum specific to ovine luteinizing hormone free of contaminating antibodies to nonspecific proteins and FSH was administered to adult, intact rats at a dose of 0.1 and 0.2 ml/day for five days. LHAS had no effect on the weights of the epididymis but decreased their secretory activity to castrate level. Administration of 0.2 ml of LHAS or castration resulted in a marked and comparable reduction in the weights and secretory activity of the accessory glands. LHAS, even at a lower dose (0.1 ml/day), caused a significant reduction in the content of sialic acid in the vas deferons and Cowper's glands. These results are discussed in relation to the factors that regulate the functions of the epididymis and accessory glands