Does Controlled Roughening of a Surface Increase Its Capacitance?

Miniature electrodes are in growing demand for applications such as medical sensing and alternative energy technologies. The potential for increasing the capacitance of such electrodes by roughening the surface was investigated, which may allow for further miniaturization. Although roughening the surface did increase the capacitance, nanometer-scale roughness seems to reduce the capacitor ideality. This indicates that the roughening techniques should increase micron-scale roughness while minimizing nanometer-scale roughness. Electrodeposition of gold nanoparticles was found to achieve this goal

The Role of Integrins in Cellular Response to Mechanical Stimuli

Tissue cells exhibit varying responses according to the stiffness of their extracellular matrix (ECM). The mechanism of this stiffness sensing is not fully understood; however, it is known that cells probe stiffness by applying intracellular force to the ECM via integrin-mediated focal adhesions. The bonds between integrins and ECM have been described as “catch bonds”, and it is unclear how ECM viscoelasticity affects these bonds. We have observed the effects of ECM stiffness on the binding strength of integrins to ECM ligands by measuring the dissociation force of individual integrin-ligand bonds of 3T3 fibroblasts on collagen-coated polyacrylamide gels using atomic force microscopy. Results show that integrins exhibit higher rates of activation on stiff substrates. Furthermore, increased matrix stiffness results in the occurrence of larger, multi-bond dissociation events, which suggests that substrate stiffness may affect the cellular response by promoting integrin clustering as well as by modulating the maximum possible force between individual integrins and the ECM

The Future of Fuel Cells in Australia

The Alternative Technology Association requested a comprehensive review of the current status of fuel cell technologies in support of a policy recommendation regarding the possible future application of fuel cell technology in a residential setting. We conducted interviews with key informants and a literature review to explore fuel cell technology in depth, as well as implementing a survey to assess the knowledge and opinions of the ATA membership. We then analysed these data to create a detailed recommendation to the ATA

sj-pdf-1-jva-10.1177_11297298231222929 – Supplemental material for Major immediate insertion-related complications after central venous catheterisation and associations with mortality, length of hospital stay, and costs: A prospective observational study

Supplemental material, sj-pdf-1-jva-10.1177_11297298231222929 for Major immediate insertion-related complications after central venous catheterisation and associations with mortality, length of hospital stay, and costs: A prospective observational study by Sofia Ingefors, Maria Adrian, Gawain Heckley, Ola Borgquist and Thomas Kander in The Journal of Vascular Access</p

Bio-Inspired Cryo-Ink Preserves Red Blood Cell Phenotype and Function During Nanoliter Vitrification

Current red blood cell cryopreservation methods utilize bulk volumes, causing cryo-injury of cells, which results in irreversible disruption of cell morphology, mechanics, and function. An innovative approach to preserve human red blood cell morphology, mechanics, and function following vitrification in nanoliter volumes is developed using a novel cryo-ink integrated with a bio-printing approach

A Petition for the Establishment of a Chapter of the Society of the Sigma Xi at the U.S. Naval Postgraduate School

A petition to the President of the Executive Committee and members of Sigma XI by NPS members organized as a Club to establish a Chapter at the U.S. Naval Postgraduate School.Approved for public release; distribution is unlimited