Additional file 18: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Additional Figure SF6: Forest plot of the association of A: CD36 (rs3211938), B: LOC441108 (rs2522051), C: RTN3 (rs542998) and D: P4HA2 (rs156029) with antibody levels to AMA1, MSP1, MSP2 and NANP. Forest plots of the betas obtained from meta-analysis of results obtained from linear regression models of SNP with logged antibody levels, adjusted for relevant clinical covariates

COVID-19 Host Genetics Initiative. A first update on mapping the human genetic architecture of COVID-19

The COVID-19 pandemic continues to pose a major public health threat, especially in countries with low vaccination rates. To better understand the biological underpinnings of SARS-CoV-2 infection and COVID-19 severity, we formed the COVID-19 Host Genetics Initiative1. Here we present a genome-wide association study meta-analysis of up to 125,584 cases and over 2.5 million control individuals across 60 studies from 25 countries, adding 11 genome-wide significant loci compared with those previously identified2. Genes at new loci, including SFTPD, MUC5B and ACE2, reveal compelling insights regarding disease susceptibility and severity.</p