Study of Propanil Induced Toxicity on Heamatological Parameter and Amelioration by Taurine in Mice

This study was carried out to evaluate in vivo protective role of taurine on toxic effect caused by propanil in mice on the hematological values. Methods: In an experimental study 24 albino mice were distributed in six equal groups of six animals in each as follows

MFS transportome of the human pathogenic yeast Candida albicans

<p>Abstract</p> <p>Background</p> <p>The major facilitator superfamily (MFS) is one of the two largest superfamilies of membrane transporters present ubiquitously in bacteria, archaea, and eukarya and includes members that function as uniporters, symporters or antiporters. We report here the complete transportome of MFS proteins of a human pathogenic yeast <it>Candida albicans</it>.</p> <p>Results</p> <p>Computational analysis of <it>C. albicans </it>genome enabled us to identify 95 potential MFS proteins which clustered into 17 families using Saier's Transport Commission (TC) system. Among these SP, DHA1, DHA2 and ACS represented major families consisting of 22, 22, 9 and 16 members, respectively. Family designations in <it>C. albicans </it>were validated by subjecting <it>Saccharomyces cerevisiae </it>genome to TC system. Based on the published available genomics/proteomics data, 87 of the putative MFS genes of <it>C. albicans </it>were found to express either at mRNA or protein levels. We checked the expression of the remaining 8 genes by using RT-PCR and observed that they are not expressed under basal growth conditions implying that either these 8 genes are expressed under specific growth conditions or they may be candidates for pseudogenes.</p> <p>Conclusion</p> <p>The <it>in silico </it>characterisation of MFS transporters in <it>Candida albicans </it>genome revealed a large complement of MFS transporters with most of them showing expression. Considering the clinical relevance of <it>C. albicans </it>and role of MFS members in antifungal resistance and nutrient transport, this analysis would pave way for identifying their physiological relevance.</p

A Novel System for Growth of Single Crystals from the Melt with an Innovative New Pulling Mechanism

This paper describes a crystal growth system employing novel concepts in fabrication of a high temperature furnace, thermocouples and a novel crystal pulling mechanism. This has reduced the costs substantially, without compromising the quality of grown crystals. The core of the furnace, a wooden cylindrical dummy had been prepared with equi-spaced helicalgroves with widths equaling the diameter of the heating wire on its outer surface machined by a lathe machine. The Kanthal heating wire was wound in the groves. It was covered with a thick layer of natural clay available locally. After the clay had dried up, an electric current was passed through the heating wire and the wooden frame was burnt out. A thick layer of theclay was applied on the inner and the outer surfaces. The furnace can operate at temperatures up to about 1000 °C. The temperature was measured with a chromel-alumel thermocouple prepared by an ingenious spot-welding technique established in the laboratory. The seed holder was hanged above the melt kept in the crucible with help of a float kept in awater container, which has a small tap at the bottom. When the tap is opened the float goes down and the seed assembly goes up. In this manner a quality pulling system, without any motor has been developed and reported here. It has been possible to grow good quality crystals of potassium chloride with excellent diameter control

A Novel System for Growth of Single Crystals from the Melt with an Innovative New Pulling Mechanism

665-670This paper describes a crystal growth system employing novel concepts in fabrication of a high temperature furnace, thermocouples and a novel crystal pulling mechanism. This has reduced the costs substantially, without compromising the quality of grown crystals. The core of the furnace, a wooden cylindrical dummy had been prepared with equi-spaced helical groves with widths equaling the diameter of the heating wire on its outer surface machined by a lathe machine. The Kanthal heating wire was wound in the groves. It was covered with a thick layer of natural clay available locally. After the clay had dried up, an electric current was passed through the heating wire and the wooden frame was burnt out. A thick layer of the clay was applied on the inner and the outer surfaces. The furnace can operate at temperatures up to about 1000 °C. The temperature was measured with a chromel-alumel thermocouple prepared by an ingenious spot-welding technique established in the laboratory. The seed holder was hanged above the melt kept in the crucible with help of a float kept in a water container, which has a small tap at the bottom. When the tap is opened the float goes down and the seed assembly goes up. In this manner a quality pulling system, without any motor has been developed and reported here. It has been possible to grow good quality crystals of potassium chloride with excellent diameter control

High resolution mapping of QTLs for fruit color and firmness in Amrapali/Sensation mango hybrids

IntroductionMango (Mangifera indica L.), acclaimed as the ‘king of fruits’ in the tropical world, has historical, religious, and economic values. It is grown commercially in more than 100 countries, and fresh mango world trade accounts for ~3,200 million US dollars for the year 2020. Mango is widely cultivated in sub-tropical and tropical regions of the world, with India, China, and Thailand being the top three producers. Mango fruit is adored for its taste, color, flavor, and aroma. Fruit color and firmness are important fruit quality traits for consumer acceptance, but their genetics is poorly understood.MethodsFor mapping of fruit color and firmness, mango varieties Amrapali and Sensation, having contrasting fruit quality traits, were crossed for the development of a mapping population. Ninety-two bi-parental progenies obtained from this cross were used for the construction of a high-density linkage map and identification of QTLs. Genotyping was carried out using an 80K SNP chip array.Results and discussionInitially, we constructed two high-density linkage maps based on the segregation of female and male parents. A female map with 3,213 SNPs and male map with 1,781 SNPs were distributed on 20 linkages groups covering map lengths of 2,844.39 and 2,684.22cM, respectively. Finally, the integrated map was constructed comprised of 4,361 SNP markers distributed on 20 linkage groups, which consisted of the chromosome haploid number in Mangifera indica (n =20). The integrated genetic map covered the entire genome of Mangifera indica cv. Dashehari, with a total genetic distance of 2,982.75 cM and an average distance between markers of 0.68 cM. The length of LGs varied from 85.78 to 218.28 cM, with a mean size of 149.14 cM. Phenotyping for fruit color and firmness traits was done for two consecutive seasons. We identified important consistent QTLs for 12 out of 20 traits, with integrated genetic linkages having significant LOD scores in at least one season. Important consistent QTLs for fruit peel color are located at Chr 3 and 18, and firmness on Chr 11 and 20. The QTLs mapped in this study would be useful in the marker-assisted breeding of mango for improved efficiency

Design and Implementation of Home Monitoring System Using RF Technology

Abstract- Home monitoring system uses the RF technology to monitor the status and control the electric device. The system has been developed to save energy. The system is implemented using modules which are capable of communicating with each other. In the existing method we can control the device like ON/OFF of the device remotely but we cannot know the status of the device whether the device is working or not. In the proposed method we overcome this disadvantage by providing good solution for monitoring and controlling of the LED’s from the remote locations. The modules are designed using ARMLPC148 and AT89S52 microcontrollers, comparator-LM324 IC, CC2500 RF transceivers which are powered by a battery source. LED is used as device which is interfaced with AT89S52 and status of the LED can be monitored on LCD interfaced with LPC2148.This paper focuses on the software aspects of the design

Yoga perspective on personal excellence and well-being

The discussions on conceptualization, operationalization, measures, and means of well-being (WB) and personal excellence (PE) are dynamic and debatable. Therefore, this study aims to coin a perspective of PE based on the Patanjali Yoga Sūtra (PYS). For this, professional, psychological, philosophical, and yogic perspectives of WB and PE are analyzed to derive a viable yogic framework for PE. The WB and the consciousness-based constructs of PE are discussed in terms of psychic tensions (PTs) (nescience, egoism, attachment, aversion, and love for life), yogic hindrances (YHs) (illness, apathy, doubt, procrastination, laziness, over somatosensory indulgence, delusion, inability, and unstable progress), psychosomatic impairments (pain, despair, tremors, arrhythmic breath), and yogic aids (wellness, intrinsic motivation, faith, role punctuality, physical activity, sensory control, clarity, competence, and sustainable progress). The PYS operationalizes PE as the dynamic level of WB and self-awareness until one attains Dharmamegha Samādhi (super consciousness). Lastly, Ashtanga Yoga (AY) is discussed as a universal principle, process, and practice for thinning PTs, vanishing YHs, empowering holistic WB, awakening extrasensory potentials, advancing self-awareness, and PE. This study will be a pioneering base for further observational and interventional studies to develop measures and personalized protocols for PE

Relationship of Nitrogen Use Efficiency with the Activities of Enzymes Involved in Nitrogen Uptake and Assimilation of Finger Millet Genotypes Grown under Different Nitrogen Inputs

Nitrogen responsiveness of three-finger millet genotypes (differing in their seed coat colour) PRM-1 (brown), PRM-701 (golden), and PRM-801 (white) grown under different nitrogen doses was determined by analyzing the growth, yield parameters and activities of nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase; GOGAT, and glutamate dehydrogenase (GDH) at different developmental stages. High nitrogen use efficiency and nitrogen utilization efficiency were observed in PRM-1 genotype, whereas high nitrogen uptake efficiency was observed in PRM-801 genotype. At grain filling nitrogen uptake efficiency in PRM-1 negatively correlated with NR, GS, GOGAT activities whereas it was positively correlated in PRM-701 and PRM-801, however, GDH showed a negative correlation. Growth and yield parameters indicated that PRM-1 responds well at high nitrogen conditions while PRM-701 and PRM-801 respond well at normal and low nitrogen conditions respectively. The study indicates that PRM-1 is high nitrogen responsive and has high nitrogen use efficiency, whereas golden PRM-701 and white PRM-801 are low nitrogen responsive genotypes and have low nitrogen use efficiency. However, the crude grain protein content was higher in PRM-801 genotype followed by PRM-701 and PRM-1, indicating negative correlation of nitrogen use efficiency with source to sink relationship in terms of seed protein content

Linear kinetic Alfvén waves in inhomogeneous plasma: Effects of Landau damping

The turbulent spectrum of kinetic Alfvén waves in inhomogeneous plasma is investigated in the presence of Landau damping. Inhomogeneities in transverse and parallel directions to the ambient magnetic field are incorporated in the dynamics. Numerical solutions of the equations governing kinetic Alfvén waves in the linear regime are obtained while retaining the effects of Landau damping, which have a significant impact on the frequency spectrum generated by propagating kinetic Alfvén waves. A semi-analytical model developed to elucidate the physics of this process is also described

Article ID 625731

Nitrogen responsiveness of three-finger millet genotypes (differing in their seed coat colour) PRM-1 (brown), PRM-701 (golden), and PRM-801 (white) grown under different nitrogen doses was determined by analyzing the growth, yield parameters and activities of nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase; GOGAT, and glutamate dehydrogenase (GDH) at different developmental stages. High nitrogen use efficiency and nitrogen utilization efficiency were observed in PRM-1 genotype, whereas high nitrogen uptake efficiency was observed in PRM-801 genotype. At grain filling nitrogen uptake efficiency in PRM-1 negatively correlated with NR, GS, GOGAT activities whereas it was positively correlated in PRM-701 and PRM-801, however, GDH showed a negative correlation. Growth and yield parameters indicated that PRM-1 responds well at high nitrogen conditions while PRM-701 and PRM-801 respond well at normal and low nitrogen conditions respectively. The study indicates that PRM-1 is high nitrogen responsive and has high nitrogen use efficiency, whereas golden PRM-701 and white PRM-801 are low nitrogen responsive genotypes and have low nitrogen use efficiency. However, the crude grain protein content was higher in PRM-801 genotype followed by PRM-701 and PRM-1, indicating negative correlation of nitrogen use efficiency with source to sink relationship in terms of seed protein content