Anti-VEGF Agents for the Treatment of Pigment Epithelial Detachments Associated With Neovascular Age-related Macular Degeneration: An Evidence-based Approach

Editorial, No abstrac

Anti-VEGF Agents for the Treatment of Pigment Epithelial Detachments Associated With Neovascular Age-related Macular Degeneration: An Evidence-based Approach

Editorial, No abstrac

Keratoconus: is it a Non-inflammatory Disease?

Editorial/No abstrac

Late-Onset Anterior Dislocation of a Posterior Chamber Intraocular Lens in a Patient with Pseudoexfoliation Syndrome

Here, we report on a patient with pseudoexfoliation syndrome who developed acute angle-closure glaucoma with a marked myopic shift due to anterior dislocation of the posterior chamber intraocular lens almost 16 months after an uneventful phacoemulsification. Examination with a Scheimpflug camera was extremely useful in confirming the diagnosis. This is the fist case of late-onset angle-closure glaucoma with a significant myopic shift due to anterior dislocation of the posterior chamber intraocular lens, which resulted in a permanent alteration of the postoperative target refraction

Simulation of Corneal imaging properties for near objects

Purpose Using raytracing simulation to study the effect of corneal imaging metrics for different aperture sizes as a function of object distances with different schematic model eyes. Methods This raytracing simulation determined the best focus (with the least root‐mean‐square (rms) ray scatter) and the best wavefront focus (with least rms wavefront error) for four schematic model eyes (Liou‐Brennan (LBME), Atchison (ATCHME), Gullstrand (GULLME) and Navarro (NAVME)) with 4 aperture sizes (2–5 mm) and 30 object distances in a logscale from 10 cm to 10 m plus infinity. For each configuration, 10,000 rays were traced through the cornea, and the aperture stop was located at the lens front apex plane as described in the model eyes. The wavefront was decomposed into Zernike components to extract the spherical aberration term. Results The focal distance with respect to the corneal front apex increases from around 31 mm for objects at infinity to around 40 mm for objects at 10 cm. The best (wavefront) focus was systematically closer to the cornea compared with the paraxial focus, and the overestimation of focal length with the paraxial focus was larger for large aperture sizes and small object distances. The rms ray scatter and wavefront error were both systematically larger with large aperture and small object sizes. At best focus the rms wavefront error was systematically larger, and the rms ray scatter was systematically smaller compared to the best wavefront focus. Spherical aberration varied more with GULLME than with LBME or NAVME, and increased strongly at smaller object distances. Conclusions The imaging properties of the cornea, especially spherical aberration, increase strongly as the object distance decreases. This effect should be considered, especially when considering aberration correcting lenses for near vision such as multifocal or enhanced depth of focus lenses