Plasma homocysteine and the severity of heart failure in patients with previous myocardial infarction

Background: Homocysteine is considered to be a risk factor, or an indicator of risk, for the development of cardiovascular disease. Little data is available on its significance in patients with previous myocardial infarction. The aim of our study was to assess the plasma level of homocysteine and its relationship with the severity of heart failure in patients with chronic myocardial infarction. Methods: We studied 144 patients with previous myocardial infarction. Patients were divided into two groups according to the presence or absence of heart failure, as certified by clinical evidence of heart failure and by echocardiographic criteria for left ventricular systolic dysfunction. Results: Of the patients with prior myocardial infarction (144; 63.6 ± 9.6 years) included in the study, 65 had heart failure. The mean level of homocysteine was significantly higher in the heart failure group (18.9 mmol/L) than in the non-heart failure group (14.1 mmol/L; p ≤ 0.001). Our study demonstrated that there is a statistically significant correlation between homocysteine plasma levels and the severity of heart failure in patients with prior myocardial infarction. Homocysteine levels have proved to become higher with NYHA class progression. A significant cross-sectional correlation has been assessed between homocysteine and tissue Doppler echocardiography parameters. Conclusions: Increased plasma homocysteine levels independently correlate with the severity of heart failure in patients with chronic myocardial infarction. We suggest that homocysteine can be used in clinical practice as a valuable heart failure risk marker in patients with chronic myocardial infarction. (Cardiol J 2011; 18, 1: 55-62

L'association leucémie lymphoïde chronique et cancer secondaire du rein (à propos de quatre observations)

PARIS-BIUM (751062103) / SudocCentre Technique Livre Ens. Sup. (774682301) / SudocSudocFranceF

Le syndrome d'activation macrophagique (cinq observations)

PARIS6-Bibl.Pitié-Salpêtrie (751132101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Le syndrome de Lemierre (étude de 3 cas et revue de la littérature)

PARIS6-Bibl. St Antoine CHU (751122104) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Les recommandations de la société Française de Médecine du sport relatives à la délivrance d'un certificat médical de non contre-indication à la pratique du football en compétition sont-elles réspectées chez des sportifs masculins amateurs de la catégorie vétérans (Plus de 35 ans) ?

LE KREMLIN-B.- PARIS 11-BU Méd (940432101) / SudocSudocFranceF

Actualité médicale de la loi de Moïse à travers l'étude du syndrome d'épuisement

La loi biblique de Moïse que constitue le Pentateuque est-elle porteuse de mesures de prévention sanitaire, en particulier pour protéger du Syndrome d Epuisement? La comparaison de ces lois avec celles des civilisations du Proche Orient Ancien démontre qu elles en sont culturellement imprégnées, mais que le monothéisme qui les inspire leur donne une grande particularité.Trois catégories de lois concernent la prévention des pathologies du stress : les sabbats, les lois alimentaires, la législation familiale et sociale. Les recherches scientifiques montrent que les lois établies dans le désert du Sinaï n ont qu un intérêt relatif dans ce domaine, tandis que les lois des deux premiers chapitres de la Genèse apparaissent comme physiologiques.L étude de leur possible application permet de faire des propositions de prescriptions.Néanmoins, il apparaît que le sens premier de ces lois est avant tout spirituel.Does the biblical Law of Moses, or Pentateuch, provide measures of sanitary prevention, particularly to protect against burnout? The comparison of such laws with those from the Ancient Near East shows evidence of being culturally immersed, but their monotheistic nature grants them a great particularity. Three categories of laws concern the prevention of stress-related pathologies: the Sabbaths, laws concerning food, family and social legislation. Scientific research shows that the laws established in the Sinai Desert merely hold little pertinence in this field; however the laws given in the first two chapters of Genesis appear as physiological. The study of their possible application allows to make proposals for prescriptions. Nevertheless, it appears that the true sense of these laws is spiritual above all.PARIS13-BU Serge Lebovici (930082101) / SudocSudocFranceF

Ostéite pubienne à propionibacterium acnes à propos de deux cas

PARIS13-BU Serge Lebovici (930082101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

ETUDE SUR LA CREATION D'UNE HOSPITALISATION A DOMICILE (A PROPOS DE L'EXPERIENCE DE COULOMMIERS)

PARIS13-BU Serge Lebovici (930082101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Maladie de Hodgkin et tumeurs solides (à propos de 3 observations)

PARIS13-BU Serge Lebovici (930082101) / SudocSudocFranceF

Trunk involvement and peau d’orange aspect are poor prognostic factors in eosinophilic fasciitis (Shulman’s disease): a multicenter retrospective study of 119 patients

International audienc