The June Days Uprising in the Epistolary Heritage of A. I. Herzen

Статья поступила в редакцию 02.03.2023 г.Статья посвящена отражению событий 23–26 июня 1848 г. в десятом письме цикла «Письма из Франции и Италии» А. И. Герцена и двух его частных письмах. Целью исследования является установление ключевых черт эпистолярного стиля литератора, а также наблюдение трансформации его рассуждений при переходе от одной словесной формы к другой. С учетом поставленной цели наиболее обоснованным представляется сравнительно-сопоставительный метод в контексте хронологического подхода. Проводится компаративный анализ данных источников, выявляется их структурное и содержательное сходство, анализируются стилистические и композиционные особенности. Результатом проделанной работы стала экспликация относительно стабильной эпистолярной манеры Герцена, определение ее основных характеристик. Сделан вывод о вспомогательной роли частной корреспонденции писателя при создании открытого цикла «Письма из Франции и Италии».The article is devoted to the reflection of the events of June 23–26, 1848 in the 10th letter of the cycle “Letters from France and Italy” by A. I. Herzen and two of his private letters. The aim of the study is to establish the key features of the writer’s epistolary style, as well as to observe the transformation of his reasoning during the transition from one verbal form to another. Taking into account the goal, the author considered a comparative method to be the most reasonable in the context of the chronological approach. A comparative analysis of these sources has been carried out, their structural and content similarity has been revealed, stylistic and compositional features has been analyzed. The result of the work done was the explication of the relatively stable epistolary manner of Herzen, the definition of its main characteristics. In addition, a conclusion was made about the auxiliary role of the writer’s private correspondence in the creation of the open cycle “Letters from Italy and France”

Лимфомы кожи: патогенетическая значимость некоторых иммунологических и биохимических показателей

The purpose of the studies was to determine pathogenetic significance of some immunologic and biochemical indicators of blood serum in patients with skin lymphomas (SL) based on the anamnesis findings and the presence of concomitant internal pathology. General clinical, immunologic, biochemical and histologic studies were carried out in 89 patients. Out of them, T-cell lymphomas — 32, B-cell lymphomas — 18, chronic dermatoses — 32 were diagnosed. It has been shown that an integrated risk factor (IRF) for LS occurrence is the highest with the pathology of barrier lymphoepithelial organs (IRF 12,66), the development of elevated sensitivity to divers types of allergens and antigens (IRF 9,03), long-term intoxication by occupational hazards (IRF-4,5). Prognostic indicators (PI) for SL development rise with disorders in metabolic (PI 14,99), detoxication (PI 14,13) liver functions, with virus infections (PI 9,71), drug misadministration (PI 6,32), hyperinsolation (PI 4,17).В работе определяли патогенетическую значимость некоторых иммунологических и биохимических показателей сыворотки крови у больных лимфомами кожи (ЛК) с учетом анамнестических данных и наличия сопутствующей патологии внутренних органов. Общеклинические, иммунологические, биохимические и гистологические исследования проведены 89 больным, диагностированы Т-клеточные лимфомы у 32, В-клеточные лимфомы — у 18, хронические дерматозы — у 32. Выявлено, что интегрированный показатель риска (ИПР) возникновения ЛК самый высокий при патологии барьерных лимфоэпителиальных органов (ИПР 12,66), развитии повышенной сенсибилизации на различные виды аллергенов и антигенов (ИПР-9,03), длительной интоксикации производственными вредными факторами (ИПР 4,5). Прогностические коэффициенты (ПК) развития ЛК увеличиваются при нарушении метаболической (ПК 14,99), детоксикационной (ПК 14,13) функций печени, при вирусных инфекциях (ПК-9,71), нерациональном применении лекарств (ПК 6,32), гиперинсоляции (ПК 4,17)

Rheology and wettability control of polymer solutions based on polyacrylamide in enhanced oil recovery

© SGEM 2017. All Rights Reserved. The current hard-to-recover oil reserves in Russia stand for more than 60% of total recoverable oil resources. These kind of reservoirs with acceptable technical and economic indicators are extracted only by applying physicochemical recovery techniques. Thus, an important relevance is given to selection of most effective EOR technology, which is directed to decrease the residual oil saturation in rock formations. Various chemical reagents including composites based on water-soluble polymers are injected both in Russia and worldwide in order to maintain reservoir pressure and to increase the oil recovery factor. The water-soluble polymers decrease the mobility difference between displacing and displaced fluids, reducing fingering effects. At the result of late water breakthrough oil recovery increases. It is highly important to introduce the model of rock matrices in order to combine the known phenomenon of natural chromatographic separation in reservoir rocks, which is characterized by heterogeneity of permeable rocks. Accordingly, heavy crude oil are located in large pores, as well as in small pores concentrated hydrocarbons. Therefore, the amount of hydrocarbon content describes the hydrophobic parameters. In this study, we combined the composite polymers with polydisperse rocks like calcite and dolomite. The different experimental results gained from using various types of rock, which is due to pore morphology and molecular interactions of polymers with rock surfaces. New laboratory results of processes, which are carried on interphase of a system: fluid reservoir - mineral matrix, are discussed.

Properties of anti-corrosive ferrite pigment synthesized with the use of production waste

© 2018, International Multidisciplinary Scientific Geoconference. All rights reserved. Pigments of the inhibitory type are the active principle of most primers used to protect metals from corrosion. Developers of anticorrosive paint and varnish materials seek to replace chromium-containing pigments, which widely used until recently due to their toxicity, with more environmentally appropriate choices. These include ferrite pigments. It is known, that the most spread method for the synthesis of ferrites, which are complex oxides or salts of ferrous acid, is the joint calcination of iron oxides with oxides having basic properties. The aim of this work is an expansion of the raw material base to produce ferritic pigments by using as one of the initial components an aspiration dust (content of iron oxide exceeds 70 %) formed as a waste in steel-casting plants. Crushed brucite (natural magnesium oxide) was used as the second component. After their thorough mixing, the resulting mixture was calcined at the reaction temperature: MgО + Fe2O3 → MgFe2O4 (1) 6MgО + 4Fe3O4 + О2 → 6MgFe2O4 (2) with obtaining of magnesium ferrite. The course of the reaction was controlled by thermogravimetry and differential thermal analysis. Ferritic-magnetite structure formation was recorded by X-ray diffraction analysis. The variation of the synthesis’s temperature-time conditions made it possible to find the optimal parameters for obtaining ferrite. The synthesized ferrite was ground on a planetary mill. The studying of the painting and technical properties of the grinding product showed that it can be used as a pigment in the production of paints and varnishes. The results of electrochemical studies of steel in contact with the aqueous extract of ferritic pigment containing 3% of sodium chloride led to the conclusion of the high ability of the resulting product to inhibit the corrosion processes

Study of the basic drinking regime of students

The aim of the study – to analyze the drinking regime of students during the educational process at the university.Цель исследования – проанализировать питьевой режим студентов во время учебного процесса в университете

The study of functional properties of drinking water «Evolet» on 3rd year students of medical and preventive faculty of the Ural state medical university

The purpose of the study is to analyze the influence of drinking water «Evolet» on the state of organism of 3-year students of medical and preventive faculty of USMU.Цель исследования. Проанализировать влияние питьевой воды «Evolet» на состояние организма студентов 3 курса медико- профилактического факультета УГМУ

The pattern of female genital hormonal disease in juvenile myoclonic epilepsy

Objective: to reveal and investigate hormonal characteristics in women of childbearing age in juvenile myoclonic epilepsy (JME).Patients and methods. The concentrations of sex steroid and tropic hormones were analyzed in 48 women of childbearing age who suffered from JME and received monotherapy or bitherapy with antiepileptic drugs (AEDs) for more than a year. For comparison of their values, a control group included 15 healthy women who did not take AEDs. Results and discussion. 66.7% of the patients were found to have ovarian hormonal dysfunction characterized by a significant increase in the level of luteinizing hormone and testosterone in the follicular phase of the cycle and a decrease in that of progesterone in the luteal phase compared with the control group. The hormonal deviations were influenced by disease duration and age-related onset in JME. Generalized tonicclonic seizures concurrent with myoclonic ones, bitherapy, and disease onset before menarche and in the period of the menstrual cycle favored the  development of hormonal deviations to a greater extent than myoclonic seizures only, monotherapy, and disease onset after the establishment of the cycle. Valproates were most commonly used in the therapy of JME; however, there were no significant differences in the hormonal deficiencies when different chemical groups of AEDs were administered

Psychosocial components of patient compliance

This literature review reflects the current understanding of patient compliance as a general medical problem. The main psychosocial factors that improve or worsen compliance considered using examples of specific nosological forms. It shown that it is precisely in the satisfaction of the patient's motives that the key moment of the “doctor-patient” system consistency lies, without which it is impossible to build an adequate patient compliance to treatmentВ представленном литературном обзоре отражены современные представления о пациентском комплаенсе как общемедицинской проблеме. Рассмотрены основные психосоциальные факторы, улучшающие либо ухудшающие комплаенс, с приведением примеров конкретных нозологических форм. Показано, что именно в удовлетворении мотивов пациента лежит ключевой момент конгруэнтности системы «врач-пациент», без чего невозможно построение адекватного медикаментозного пациентского комплаенс

Overexpression of AtCpNifS enhances selenium tolerance and accumulation in Arabidopsis

Selenium (Se) is an essential element for many organisms but is toxic at higher levels. CpNifS is a chloroplastic NifS-like protein in Arabidopsis (Arabidopsis thaliana) that can catalyze the conversion of cysteine into alanine and elemental sulfur (S 0 ) and of selenocysteine into alanine and elemental Se (Se 0 ). We overexpressed CpNifS to investigate the effects on Se metabolism in plants. CpNifS overexpression significantly enhanced selenate tolerance (1.9-fold) and Se accumulation (2.2-fold). CpNifS overexpressors showed significantly reduced Se incorporation into protein, which may explain their higher Se tolerance. Also, sulfur accumulation was enhanced by approximately 30% in CpNifS overexpressors, both on media with and without selenate. Root transcriptome changes in response to selenate mimicked the effects observed under sulfur starvation. There were only a few transcriptome differences between CpNifS-overexpressing plants and wild type, besides the 25-to 40-fold increase in CpNifS levels. Judged from x-ray analysis of near edge spectrum, both CpNifS overexpressors and wild type accumulated mostly selenate (Se VI ). In conclusion, overexpression of this plant NifS-like protein had a pronounced effect on plant Se metabolism. The observed enhanced Se accumulation and tolerance of CpNifS overexpressors show promise for use in phytoremediation