Quenched Spin Tunneling and Diabolical Points in Magnetic Molecules: II. Asymmetric Configurations

The perfect quenching of spin tunneling first predicted for a model with biaxial symmetry, and recently observed in the magnetic molecule Fe_8, is further studied using the discrete phase integral (or Wentzel-Kramers-Brillouin) method. The analysis of the previous paper is extended to the case where the magnetic field has both hard and easy components, so that the Hamiltonian has no obvious symmetry. Herring's formula is now inapplicable, so the problem is solved by finding the wavefunction and using connection formulas at every turning point. A general formula for the energy surface in the vicinity of the diabolo is obtained in this way. This formula gives the tunneling apmplitude between two wells unrelated by symmetry in terms of a small number of action integrals, and appears to be generally valid, even for problems where the recursion contains more than five terms. Explicit results are obtained for the diabolical points in the model for Fe_8. These results exactly parallel the experimental observations. It is found that the leading semiclassical results for the diabolical points appear to be exact, and the points themselves lie on a perfect centered rectangular lattice in the magnetic field space. A variety of evidence in favor of this perfect lattice hypothesis is presented.Comment: Revtex; 4 ps figures; follow up to cond-mat/000311

Standard Infection Control Practices among Peripheral Health Care Workers: A Knowledge, Attitude and Practice Study from a Rural Haryana

Background: Globally, around 2.5% of HIV and 40% of HBV among Health Care Workers (HCWs) are attributed to occupational exposure with an overall incidence of occupational exposure to blood/body fluids among HCW as 32.3%. There exists a gap between the knowledge and practice of standard infection control practices among HCW. Failure to follow these standard protocols leads to loss of precious work hours of this skilled work force.Methods: To know the knowledge, attitude and practice regarding standard infection control protocols, a community based, cross- sectional, analytical, non –interventional study was planned among health care workers at a Rural Community Health Centre (CHC) , Dighal of district Jhajjar (Haryana). A total of 50 HCWs were included in the study. The study was conducted during the months of July –August, 2016.Results: About 56% of HCWs were having the knowledge about the correct steps of hand washing but only 20% were actually practicing hand washing before administrating injections. Only 28% of participants were correctly using hub-cutter and needle destroyers after the injection practices. It was observed that 42% of subjects were still trying to re-cap needles after the injections. 60% of subjects felt that using standard precautions was cumbersome. 74% of the subjects felt that using standard precautions was expensive. 54% of study subjects felt that it was difficult to follow stand precautions in government institutions due to logistics issues. Only 28% of the participants had received complete vaccination against Hepatitis B.Conclusion: There exists a huge gap between the knowledge and practice of standard infection control protocols. Among most of the HCWs, the attitude was not positive towards using standard precautions despite having knowledge. Lack of initiative from the higher up officials, poor training, poor monitoring further complex the issue. Regular monitoring and supervision, capacity building of HCWs along with regular logistic supply are recommended

Mobile agent location management in global networks

Mobility management is a necessity in highly dynamic and large-scale Mobile Agents (MAs) networks, especially in a multi-region environment in order to control and communicate with agents after launching. Existing mechanisms for locating MAs are not efficient as these do not consider the effect of location updates on migration time and produce network overload. This paper presents a hierarchical model for location management of MAs in global networks. Three protocols are developed, namely search, update and search-update. The location management technique uses one combination of search, update and search-update protocols throughout execution. Three cases are considered for Update and Search-Update Protocols. Thus, nine combinations of location management protocols are generated, from which an agent can dynamically select one as per requirement, to communicate with other agents on the global network. We have implemented these protocols on the system developed at IIT Roorkee, to evaluate the performance. Results indicate that overhead generated by these protocols does not affect the actual agent response and migration time[1].  

The Borexino Thermal Monitoring & Management System and simulations of the fluid-dynamics of the Borexino detector under asymmetrical, changing boundary conditions

A comprehensive monitoring system for the thermal environment inside the Borexino neutrino detector was developed and installed in order to reduce uncertainties in determining temperatures throughout the detector. A complementary thermal management system limits undesirable thermal couplings between the environment and Borexino's active sections. This strategy is bringing improved radioactive background conditions to the region of interest for the physics signal thanks to reduced fluid mixing induced in the liquid scintillator. Although fluid-dynamical equilibrium has not yet been fully reached, and thermal fine-tuning is possible, the system has proven extremely effective at stabilizing the detector's thermal conditions while offering precise insights into its mechanisms of internal thermal transport. Furthermore, a Computational Fluid-Dynamics analysis has been performed, based on the empirical measurements provided by the thermal monitoring system, and providing information into present and future thermal trends. A two-dimensional modeling approach was implemented in order to achieve a proper understanding of the thermal and fluid-dynamics in Borexino. It was optimized for different regions and periods of interest, focusing on the most critical effects that were identified as influencing background concentrations. Literature experimental case studies were reproduced to benchmark the method and settings, and a Borexino-specific benchmark was implemented in order to validate the modeling approach for thermal transport. Finally, fully-convective models were applied to understand general and specific fluid motions impacting the detector's Active Volume.Comment: arXiv admin note: substantial text overlap with arXiv:1705.09078, arXiv:1705.0965

Bell inequalities as constraints on unmeasurable correlations

The interpretation of the violation of Bell-Clauser-Horne inequalities is revisited, in relation with the notion of extension of QM predictions to unmeasurable correlations. Such extensions are compatible with QM predictions in many cases, in particular for observables with compatibility relations described by tree graphs. This implies classical representability of any set of correlations , , , and the equivalence of the Bell-Clauser-Horne inequalities to a non void intersection between the ranges of values for the unmeasurable correlation associated to different choices for B. The same analysis applies to the Hardy model and to the "perfect correlations" discussed by Greenberger, Horne, Shimony and Zeilinger. In all the cases, the dependence of an unmeasurable correlation on a set of variables allowing for a classical representation is the only basis for arguments about violations of locality and causality.Comment: Some modifications have been done in order to improve clarity of presentation and comparison with other approache

Quantum Locality

It is argued that while quantum mechanics contains nonlocal or entangled states, the instantaneous or nonlocal influences sometimes thought to be present due to violations of Bell inequalities in fact arise from mistaken attempts to apply classical concepts and introduce probabilities in a manner inconsistent with the Hilbert space structure of standard quantum mechanics. Instead, Einstein locality is a valid quantum principle: objective properties of individual quantum systems do not change when something is done to another noninteracting system. There is no reason to suspect any conflict between quantum theory and special relativity.Comment: Introduction has been revised, references added, minor corrections elsewhere. To appear in Foundations of Physic

Onset of Superfluidity in 4He Films Adsorbed on Disordered Substrates

We have studied 4He films adsorbed in two porous glasses, aerogel and Vycor, using high precision torsional oscillator and DC calorimetry techniques. Our investigation focused on the onset of superfluidity at low temperatures as the 4He coverage is increased. Torsional oscillator measurements of the 4He-aerogel system were used to determine the superfluid density of films with transition temperatures as low as 20 mK. Heat capacity measurements of the 4He-Vycor system probed the excitation spectrum of both non-superfluid and superfluid films for temperatures down to 10 mK. Both sets of measurements suggest that the critical coverage for the onset of superfluidity corresponds to a mobility edge in the chemical potential, so that the onset transition is the bosonic analog of a superconductor-insulator transition. The superfluid density measurements, however, are not in agreement with the scaling theory of an onset transition from a gapless, Bose glass phase to a superfluid. The heat capacity measurements show that the non-superfluid phase is better characterized as an insulator with a gap.Comment: 15 pages (RevTex), 21 figures (postscript

Identification of 181Hg and shape coexistence in odd-A Hg isotopes

In-beam γ-ray transitions in 181Hg, the lightest odd-A Hg isotope known thus far, have been identified from fragment mass-γ and γ-γ coincidence measurements. Five prolate deformed rotational bands were placed in the level scheme. A decoupled band built on the strongly prolate deformed 1/2-[521] ground state was observed up to 29/2-. A 5/2-[512] configuration is suggested for a pair of strongly coupled bands displaying no signature splitting. The other two bands are also signature partner bands. They are populated with the largest intensity and exhibit splitting. They have been associated with the mixed neutron i13/2 orbitals and are proposed to decay to an i13/2 isomeric state associated with an oblate state

Vibrio parahaemolyticus, enterotoxigenic Escherichia coli, enterohemorrhagic Escherichia coli and Vibrio cholerae

This review highlighted the following: (i) pathogenic mechanism of the thermostable direct hemolysin produced by Vibrio parahaemolyticus, especially on its cardiotoxicity, (ii) heat-labile and heat-stable enterotoxins produced by enterotoxigenic Escherichia coli, especially structure–activity relationship of heat-stable enterotoxin, (iii) RNA N-glycosidase activity of Vero toxins (VT1 and VT2) produced by enterohemorrhagic Escherichia coli O157:H7, (iv) discovery of Vibrio cholerae O139, (v) isolation of new variant of Vibrio cholerae O1 El Tor that carries classical ctxB, and production of high concentration of cholera toxin by these strains, and (vi) conversion of viable but nonculturable (VBNC) Vibrio cholerae to culturable state by co-culture with eukaryotic cells

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume

The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised measures of age acceleration, based on DNA methylation patterns (DNAm age), and cross-sectional and longitudinal cognition and AD-related neuroimaging phenotypes (volumetric MRI and Amyloid-β PET) in the Australian Imaging, Biomarkers and Lifestyle (AIBL) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Significant associations were observed between age acceleration using the Hannum epigenetic clock and cross-sectional hippocampal volume in AIBL and replicated in ADNI. In AIBL, several other findings were observed cross-sectionally, including a significant association between hippocampal volume and the Hannum and Phenoage epigenetic clocks. Further, significant associations were also observed between hippocampal volume and the Zhang and Phenoage epigenetic clocks within Amyloid-β positive individuals. However, these were not validated within the ADNI cohort. No associations between age acceleration and other Alzheimer’s disease-related phenotypes, including measures of cognition or brain Amyloid-β burden, were observed, and there was no association with longitudinal change in any phenotype. This study presents a link between age acceleration, as determined using DNA methylation, and hippocampal volume that was statistically significant across two highly characterised cohorts. The results presented in this study contribute to a growing literature that supports the role of epigenetic modifications in ageing and AD-related phenotypes