115 research outputs found
Realizing bright-matter-wave-soliton collisions with controlled relative phase
We propose a method to split the ground state of an attractively interacting atomic Bose-Einstein condensate into two bright solitary waves with controlled relative phase and velocity. We analyze the stability of these waves against their subsequent recollisions at the center of a cylindrically symmetric, prolate harmonic trap as a function of relative phase, velocity, and trap anisotropy. We show that the collisional stability is strongly dependent on relative phase at low velocity, and we identify previously unobserved oscillations in the collisional stability as a function of the trap anisotropy. An experimental implementation of our method would determine the validity of the mean-field description of bright solitary waves and could prove to be an important step toward atom interferometry experiments involving bright solitary waves
Phonon Dispersion Relations in PrBa2Cu3O6+x (x ~ 0.2)
We report measurements of the phonon dispersion relations in
non-superconducting, oxygen-deficient PrBa2Cu3O6+x (x ~ 0.2) by inelastic
neutron scattering. The data are compared with a model of the lattice dynamics
based on a common interaction potential. Good agreement is achieved for all but
two phonon branches, which are significantly softer than predicted. These modes
are found to arise predominantly from motion of the oxygen ions in the CuO2
planes. Analogous modes in YBa2Cu3O6 are well described by the common
interaction potential model.Comment: 4 pages, 3 figures. Minor changes following referees' comment
Laser Cooling of Trapped Fermi Gases deeply below the Fermi Temperature
We study the collective Raman cooling of a polarized trapped Fermi gas in the
Festina Lente regime, when the heating effects associated with photon
reabsorptions are suppressed. We predict that by adjusting the spontaneous
Raman emission rates and using appropriately designed anharmonic traps,
temperatures of the order of 2.7% of the Fermi temperature can be achieved in
3D.Comment: 4 pages, 3 figures; final versio
Entanglement transfer from dissociated molecules to photons
We introduce and study the concept of a reversible transfer of the quantum
state of two internally-translationally entangled fragments, formed by
molecular dissociation, to a photon pair. The transfer is based on intracavity
stimulated Raman adiabatic passage and it requires a combination of processes
whose principles are well established.Comment: 5 pages, 3 figure
Generation of 3 spinocerebellar ataxia type 1 (SCA1) patient-derived induced pluripotent stem cell lines LUMCi002-A, B, and C and 2 unaffected sibling control induced pluripotent stem cell lines LUMCi003-A and B
Spinocerebellar ataxia type 1 (SCA1) is a hereditary neurodegenerative disease caused by a CAG repeat expansion in exon 8 of the ATXN1 gene. We generated induced pluripotent stem cells (hiPSCs) from a SCA1 patient and his non-affected sister by using non-integrating Sendai Viruses (SeV). The resulting hiPSCs are SeVfree, express pluripotency markers, display a normal karyotype, retain the mutation (length of the CAG repeat expansion in the ATXN1 gene) and are able to differentiate into the three germ layers in vitro
Number--conserving model for boson pairing
An independent pair ansatz is developed for the many body wavefunction of
dilute Bose systems. The pair correlation is optimized by minimizing the
expectation value of the full hamiltonian (rather than the truncated Bogoliubov
one) providing a rigorous energy upper bound. In contrast with the Jastrow
model, hypernetted chain theory provides closed-form exactly solvable equations
for the optimized pair correlation. The model involves both condensate and
coherent pairing with number conservation and kinetic energy sum rules
satisfied exactly and the compressibility sum rule obeyed at low density. We
compute, for bulk boson matter at a given density and zero temperature, (i) the
two--body distribution function, (ii) the energy per particle, (iii) the sound
velocity, (iv) the chemical potential, (v) the momentum distribution and its
condensate fraction and (vi) the pairing function, which quantifies the ODLRO
resulting from the structural properties of the two--particle density matrix.
The connections with the low--density expansion and Bogoliubov theory are
analyzed at different density values, including the density and scattering
length regime of interest of trapped-atoms Bose--Einstein condensates.
Comparison with the available Diffusion Monte Carlo results is also made.Comment: 21 pages, 12 figure
Implications of Space-Time foam for Entanglement Correlations of Neutral Kaons
The role of invariance and consequences for bipartite entanglement of
neutral (K) mesons are discussed. A relaxation of leads to a modification
of the entanglement which is known as the effect. The relaxation of
assumptions required to prove the theorem are examined within the context
of models of space-time foam. It is shown that the evasion of the EPR type
entanglement implied by (which is connected with spin statistics) is
rather elusive. Relaxation of locality (through non-commutative geometry) or
the introduction of decoherence by themselves do not lead to a destruction of
the entanglement. So far we find only one model which is based on non-critical
strings and D-particle capture and recoil that leads to a stochastic
contribution to the space-time metric and consequent change in the neutral
meson bipartite entanglement. The lack of an omega effect is demonstrated for a
class of models based on thermal like baths which are generally considered as
generic models of decoherence
Decoherence and CPT Violation in a Stringy Model of Space-Time Foam
I discuss a model inspired from the string/brane framework, in which our
Universe is represented as a three brane, propagating in a bulk space time
punctured by D0-brane (D-particle) defects. As the D3-brane world moves in the
bulk, the D-particles cross it, and from an effective observer on D3 the
situation looks like a ``space-time foam'' with the defects ``flashing'' on and
off (``D-particle foam''). The open strings, with their ends attached on the
brane, which represent matter in this scenario, can interact with the
D-particles on the D3-brane universe in a topologically non-trivial manner,
involving splitting and capture of the strings by the D0-brane defects. Such
processes are described by logarithmic conformal field theories on the
world-sheet. Physically, they result in effective decoherence of the string
matter on the D3 brane, and as a result, of CPT Violation, but of a type that
implies an ill-defined nature of the effective CPT operator. Due to electric
charge conservation, only electrically neutral (string) matter can exhibit such
interactions with the D-particle foam. This may have unique, experimentally
detectable, consequences for electrically-neutral entangled quantum matter
states on the brane world, in particular the modification of the pertinent EPR
Correlation of neutral mesons in a meson factory.Comment: 41 pages Latex, five eps figures incorporated. Uses special macro
Normal range CAG repeat size variations in the HTT gene are associated with an adverse lipoprotein profile partially mediated by body mass index
Tandem cytosine-adenine-guanine (CAG) repeat sizes of 36 or more in the huntingtin gene (HTT) cause Huntington's disease (HD). Apart from neuropsychiatric complications, the disease is also accompanied by metabolic dysregulation and weight loss, which contribute to a progressive functional decline. Recent studies also reported an association between repeats below the pathogenic threshold (Metabolic health: pathophysiological trajectories and therap
Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset
Objective We aimed to assess whether differences in energy metabolism in fibroblast cell lines derived from patients with Huntington disease were associated with age at onset independent of the cytosine-adenine-guanine (CAG) repeat number in the mutant allele. Methods For this study, we selected 9 pairs of patients with Huntington disease matched for mutant CAG repeat size and sex, but with a difference of at least 10 years in age at onset, using the Leiden Huntington disease database. From skin biopsies, we isolated fibroblasts in which we (1) quantified the ATP concentration before and after a hydrogen-peroxide challenge and (2) measured mitochondrial respiration and glycolysis in real time, using the Seahorse XF Extracellular Flux Analyzer XF24. Results The ATP concentration in fibroblasts was significantly lower in patients with Huntington disease with an earlier age at onset, independent of calendar age and disease duration. Maximal respiration, spare capacity, and respiration dependent on complex II activity, and indices of mitochondrial respiration were significantly lower in patients with Huntington disease with an earlier age at onset, again independent of calendar age and disease duration. Conclusions A less efficient bioenergetics profile was found in fibroblast cells from patients with Huntington disease with an earlier age at onset independent of mutant CAG repeat size. Thus, differences in bioenergetics could explain part of the residual variation in age at onset in Huntington disease
- …