Age as a risk factor for acute mountain sickness upon rapid ascent to 3,700 m among young adult Chinese men.

BackgroundThe aim of this study was to explore the relationship between age and acute mountain sickness (AMS) when subjects are exposed suddenly to high altitude.MethodsA total of 856 young adult men were recruited. Before and after acute altitude exposure, the Athens Insomnia Scale score (AISS) was used to evaluate the subjective sleep quality of subjects. AMS was assessed using the Lake Louise scoring system. Heart rate (HR) and arterial oxygen saturation (SaO2) were measured.ResultsResults showed that, at 500 m, AISS and insomnia prevalence were higher in older individuals. After acute exposure to altitude, the HR, AISS, and insomnia prevalence increased sharply, and the increase in older individuals was more marked. The opposite trend was observed for SaO2. At 3,700 m, the prevalence of AMS increased with age, as did severe AMS, and AMS symptoms (except gastrointestinal symptoms). Multivariate logistic regression analysis showed that age was a risk factor for AMS (adjusted odds ratio [OR] 1.07, 95% confidence interval [CI] 1.01-1.13, P<0.05), as well as AISS (adjusted OR 1.39, 95% CI 1.28-1.51, P<0.001).ConclusionThe present study is the first to demonstrate that older age is an independent risk factor for AMS upon rapid ascent to high altitude among young adult Chinese men, and pre-existing poor subjective sleep quality may be a contributor to increased AMS prevalence in older subjects

2-Hydr­oxy-6,6-dimethyl­bicyclo­[3.1.1]heptane-2-carboxylic acid

The title compound, C10H16O3, with a bicyclo­[3.1.1]heptane unit, was obtained by oxidation of β-pinene. The asymmetric unit contains two independent mol­ecules with similar geometry: the six-membered rings in both mol­ecules adopt envelope conformations. In the crystal, the independent mol­ecules exist as O—H⋯O hydrogen-bonded dimers. The dimers are linked into helical chains along the b axis by O—H⋯O hydrogen bonds

4-Isopropyl-N-phenyl­cyclo­hexa-1,3-diene-1-carboxamide

In the crystal structure of the title compound, C16H19NO, mol­ecules are linked through a pair of N—H⋯O hydrogen bonds, forming chains along the a axis

The HI Bias during the Epoch of Reionization

The neutral hydrogen (HI) and its 21 cm line are promising probes to the reionization process of the intergalactic medium (IGM). To use this probe effectively, it is imperative to have a good understanding on how the neutral hydrogen traces the underlying matter distribution. Here we study this problem using semi-numerical modeling by combining the HI in the IGM and the HI from halos during the epoch of reionization (EoR), and investigate the evolution and the scale-dependence of the neutral fraction bias as well as the 21 cm line bias. We find that the neutral fraction bias on large scales is negative during reionization, and its absolute value on large scales increases during the early stage of reionization and then decreases during the late stage. During the late stage of reionization, there is a transition scale at which the HI bias transits from negative on large scales to positive on small scales, and this scale increases as the reionization proceeds to the end.Comment: 11 pages, 11 figures, MNRAS accepte

DoSTra: Discovering common behaviors of objects using the duration of staying on each location of trajectories

Since semantic trajectories can discover more semantic meanings of a user\u27s interests without geographic restrictions, research on semantic trajectories has attracted a lot of attentions in recent years. Most existing work discover the similar behavior of moving objects through analysis of their semantic trajectory pattern, that is, sequences of locations. However, this kind of trajectories without considering the duration of staying on a location limits wild applications. For example, Tom and Anne have a common pattern of Home→Restaurant → Company → Restaurant, but they are not similar, since Tom works at Restaurant, sends snack to someone at Company and return to Restaurant while Anne has breakfast at Restaurant, works at Company and has lunch at Restaurant. If we consider duration of staying on each location we can easily to differentiate their behaviors. In this paper, we propose a novel approach for discovering common behaviors by considering the duration of staying on each location of trajectories (DoSTra). Our approach can be used to detect the group that has similar lifestyle, habit or behavior patterns and predict the future locations of moving objects. We evaluate the experiment based on synthetic dataset, which demonstrates the high effectiveness and efficiency of the proposed method