185 research outputs found
The Good, The Bad, or the Ugly? An Empirical Investigation of Revoking Behavior on eBay
In this paper, we investigate a crucial aspect of the reputation mechanism design in electronic markets – the ability of buyers and sellers to revoke or mutually withdraw negative feedback and ratings. Based on recent changes in eBay feedback mechanism, we find that the two-way reputation system enables certain sellers to behave opportunistically by revoking negative feedbacks they receive. This makes the reputation system less effective in discerning the quality of sellers. We also find that changes in the reputation system have a significant influence on these sellers’ behavior. After revoking is not possible on eBay, sellers put more efforts in the transactions. Our findings support the moral hazard assumption regarding seller’s strategic behavior. We also discuss the implications of the above findings to reputation mechanism design and practice
Effects of caesarean section on maternal health in low risk nulliparous women: a prospective matched cohort study in Shanghai, China
<p>Abstract</p> <p>Background</p> <p>Rates of caesarean section are progressively increasing in many parts of the world. As a result of psychosocial factors there has been an increasing tendency for pregnant women without justifiable medical indications for caesarean section to ask for this procedure in China. A critical examination of this issue in relation to maternal outcomes is important. At present there are no clinical trials to help assess the risks and benefits of caesarean section in low risk women. To fill the gap left by trials, this indication-matched cohort study was carried out to examine prospectively the outcomes of caesarean section on women with no absolute obstetric indication compared with similar women who had vaginal delivery.</p> <p>Methods</p> <p>An indication-matched cohort study was undertaken to compare maternal outcomes following caesarean section with those undergoing vaginal delivery, in which the two groups were matched for non-absolute indications. 301 nulliparous women with caesarean section were matched successfully with 301 women who delivered vaginally in the Maternal and Children's Hospitals (MCHs) in Shanghai, China. Logistic regression model or binomial regression model was used to estimate the relative risk (RR) directly. Adjusted RRs were calculated adjusting for propensity score and medical indications.</p> <p>Results</p> <p>The incidence of total complications was 2.2 times higher in the caesarean section group during hospitalization post-partum, compared with the vaginal delivery group (RR = 2.2; 95% CI: 1.1-4.4). The risk of haemorrhage from the start of labour until 2 hours post-partum was significantly higher in the caesarean group (RR = 5.6; 95% CI: 1.2-26.9). The risk of chronic abdominal pain was significantly higher for the caesarean section group (RR = 3.6; 95% CI: 1.2-10.9) than for the vaginal delivery group within 12 months post-partum. The two groups had similar incidences of anaemia and complicating infections such as wound complications or urinary tract infection.</p> <p>Conclusions</p> <p>In nulliparous women who were at low risk, caesarean section was associated with a higher rate of post-partum morbidity. Those requesting the surgical procedure with no conventional medical indication, should be advised of the potential risks.</p
(7R,8S,9S,12S)-1-(4-Chlorobenzyloxy)-13,14-didehydro-12-hydroxy-2,13-dimethoxy-N-methylmorphinane
The title compound, C26H30ClNO4, a sinomenine derivative, has five six-membered rings, two of which are aromatic, with a dihedral angle of 34.13 (20)° between these. The N-containing ring and the fourth ring exhibit chair conformations, while the fifth ring approximates an envelope conformation. A single intermolecular O—H⋯N hydrogen-bonding interaction gives a one-dimensional chain structure which extends along the a axis. The absolute configuration for the molecule has been determined
(7R,8S,9S,12S)-1-Benzyloxy-13,14-didehydro-12-hydroxy-2,13-dimethoxy-N-methylmorphinane
In the title compound, C26H31NO4, a sinomenine derivative, the angle between the two aromatic rings is 53.34 (4)°. The N-containing ring is in a chair conformation, while the other two non-planar rings are in a half-boat conformation. In the crystal, molecules are linked by O—H⋯N interactions into a C(8) chain along [100]
Time-reversal symmetry breaking driven topological phase transition in EuB
The interplay between time-reversal symmetry (TRS) and band topology plays a
crucial role in topological states of quantum matter. In
time-reversal-invariant (TRI) systems, the inversion of spin-degenerate bands
with opposite parity leads to nontrivial topological states, such as
topological insulators and Dirac semimetals. When the TRS is broken, the
exchange field induces spin splitting of the bands. The inversion of a pair of
spin-splitting subbands can generate more exotic topological states, such as
quantum anomalous Hall insulators and magnetic Weyl semimetals. So far, such
topological phase transitions driven by the TRS breaking have not been
visualized. In this work, using angle-resolved photoemission spectroscopy, we
have demonstrated that the TRS breaking induces a band inversion of a pair of
spin-splitting subbands at the TRI points of Brillouin zone in EuB, when a
long-range ferromagnetic order is developed. The dramatic changes in the
electronic structure result in a topological phase transition from a TRI
ordinary insulator state to a TRS-broken topological semimetal (TSM) state.
Remarkably, the magnetic TSM state has an ideal electronic structure, in which
the band crossings are located at the Fermi level without any interference from
other bands. Our findings not only reveal the topological phase transition
driven by the TRS breaking, but also provide an excellent platform to explore
novel physical behavior in the magnetic topological states of quantum matter.Comment: 22 pages, 7 figures, accepted by Phys. Rev.
Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with a strong genetic involvement and ethnic differences. Susceptibility genes identified so far only explain a small portion of the genetic heritability of SLE, suggesting that many more loci are yet to be uncovered for this disease. In this study, we performed a meta-analysis of genome-wide association studies on SLE in Chinese Han populations and followed up the findings by replication in four additional Asian cohorts with a total of 5,365 cases and 10,054 corresponding controls. We identified genetic variants in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with the disease. These findings point to potential roles of cell-cycle regulation, autophagy, and DNA demethylation in SLE pathogenesis. For the region involving TET3 and that involving CDKN1B, multiple independent SNPs were identified, highlighting a phenomenon that might partially explain the missing heritability of complex diseases
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