Evaluating E-Government Web Usability : A Case Study of Penang.Net

Electronic Government (E-Government) initiatives have often sounded very promising but been difficult to implement. Therefore, it is important to ensure that people, have opportunities to benefit from the Web by the government, especially from on-line public services or the online information. The study takes into consideration how E-Government should be understood. It presents the review of literature regarding the examination on E-government evaluation methods adopted in leading information technology advanced countries. This study aims to provide usability evaluation of the Penang state E-Government web sites: Penang.Net by using the benchmarking approach by using a form of the benchmark approach to asess the degree to which each of the web site usability and the contents usefulness. By then it contrasts the web page of the three web sites and a discussion of the best practice for various usability criteria. The result of this study can be used to inform the subsequent re-design of the Penang.Net home page. The finding is intended to measure the performance and quality of Penang.Net web against the others state government service website. The suggested guidelines established in this study aimed to provide suggestions to the Penang state government that enables then to produce E-Government web sites that are both usable and benefit to Penang people

Exploring the effects of car ownership and commuting on subjective well-being::a nationwide questionnaire study

How and to what extent household car ownership and commuting behavior affect individual subjective well-being (SWB) is of great interest for urban and transportation planning. Increasing attention has been paid to the associations between car ownership, commuting and SWB. However, only a limited number of studies examined the effects of travel-related factors on both cognitive and affective SWB aspects. This research empirically investigated the relationships from the two SWB aspects. Furthermore, we extend the modeling of generic cognitive SWB to several specific measures (e.g., satisfaction with life compared to a specific group of people, degree of free choice, social position, and social equality) to explore how car ownership and commuting behavior contribute to individual SWB. Drawing on the data derived from the 2014 China Labor-Force Dynamics Survey, a set of ordered probit models based on Bayesian inference are estimated. The findings point out that household car ownership has a significant effect on cognitive SWB but a limited influence on affective SWB. It appears that commuting time is significantly and negatively associated with individuals’ cognitive and affective well-being, whereas a positive correlation is found between the commuting by bicycle and affective SWB. The effects of commuting time and transportation modes on different measured satisfactions with life have no big differences. Finally, results of the Wald tests indicate that incorporating household car ownership and commuting behavior into the modeling framework can significantly improve the prediction accuracy of individual SWB

Novel compound heterozygous mutations in CNGA1in a Chinese family affected with autosomal recessive retinitis pigmentosa by targeted sequencing

Gene symbol list that include in the Hereditary Ophthalmological Disease GenePanel. (XLSX 12 kb

Metabolic Cell Death in Cancer: Ferroptosis, Cuproptosis, Disulfidptosis, and Beyond

Cell death resistance represents a hallmark of cancer. Recent studies have identified metabolic cell death as unique forms of regulated cell death resulting from an imbalance in the cellular metabolism. This review discusses the mechanisms of metabolic cell death-ferroptosis, cuproptosis, disulfidptosis, lysozincrosis, and alkaliptosis-and explores their potential in cancer therapy. Our review underscores the complexity of the metabolic cell death pathways and offers insights into innovative therapeutic avenues for cancer treatment