Socioeconomic status and self-rated health in China: Findings from a cross-sectional study

To investigate whether socioeconomic status is associated with the self-rated health (SRH) status among Chinese.A cross sectional study including a national sample was conducted among Chinese adults in 2008. In total, 3225 participants were selected by a multistage cluster sampling method. Both general self-rated health and time-comparative self-rated health were measured by a standardized questionnaire. Logistic regression models were used to estimate the odds ratios (ORs) (95% confidence intervals, CIs) of occupation with SRH by occupation, and adjusted for age, sex, education, area, marriage, smoking, drinking, and health status.Overall, 34.4% of study participants reported good on the general SRH (male: 35.8%; female: 32.9%) and 26.2% reported good on the time-comparative SRH (male: 27.2%; female: 25.3%). The prevalence of good general SRH varied from 28.8% to 52.8% and the prevalence of time-comparative SHR varied from 21.7% to 33.9% in different occupations. The adjusted OR (Odd Ratio) for good on the general SRH was 1.35 (95% CI: 1.20-1.52) for the occupation of civil servants, 2.23 (95% CI: 1.96-2.54) for farmers, and 1.15 (95%CI: 1.01-1.31) for businessmen. The full adjusted OR of good on the time-comparative SRH was 1.36 (95% CI: 1.17-1.58) for students and was 1.25 (95% CI: 1.10-1.42) for civil servants.In presented study, 34.4% of the participants reported good on the general SRH, and 26.2% participants reported good on the time-comparative SRH. The prevalence of good general SRH and good time-comparative SRH varied among occupations

The clinical feature of silent infections of novel coronavirus infection (COVID‐19) in Wenzhou

Here were reported clinical features of silent infected COVID‐19 patients. Our study showed that the prevalence of the silent infection of COVID‐19 is 5.8% (95% CI: 3.4‐9.9%), which is much higher than 1.2% which from the report in China CDC. The silent infection patients were more likely to be young adults, the patients without chronic disease. All of the cases in the presented study was found because they were traced as close contact of confirmed cases. Our study indicated that traced the close contract of confirmed case, long time self‐quarantine, and screening is necessary to prevent the secondary cases in community

COVID‐19 in Tuberculosis patients: a report of three cases

The clinical features and treatment of pulmonary tuberculosis patients with COVID‐19 is unclear and understudied. Here, three pulmonary tuberculosis patients with COVID‐19 infection were prospectively followed from hospital admission to discharge. We provide information and experience with treatment of pulmonary tuberculosis cases with confirmed COVID‐19 infection

Characterization of Defects in Ion Transport and Tissue Development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Knockout Rats

Animal models for cystic fibrosis (CF) have contributed significantly to our understanding of disease pathogenesis. Here we describe development and characterization of the first cystic fibrosis rat, in which the cystic fibrosis transmembrane conductance regulator gene (CFTR) was knocked out using a pair of zinc finger endonucleases (ZFN). The disrupted Cftr gene carries a 16 base pair deletion in exon 3, resulting in loss of CFTR protein expression. Breeding of heterozygous (CFTR+/−) rats resulted in Mendelian distribution of wild-type, heterozygous, and homozygous (CFTR−/−) pups. Nasal potential difference and transepithelial short circuit current measurements established a robust CF bioelectric phenotype, similar in many respects to that seen in CF patients. Young CFTR−/− rats exhibited histological abnormalities in the ileum and increased intracellular mucus in the proximal nasal septa. By six weeks of age, CFTR−/− males lacked the vas deferens bilaterally. Airway surface liquid and periciliary liquid depth were reduced, and submucosal gland size was abnormal in CFTR−/− animals. Use of ZFN based gene disruption successfully generated a CF animal model that recapitulates many aspects of human disease, and may be useful for modeling other CF genotypes, including CFTR processing defects, premature truncation alleles, and channel gating abnormalities

Ivory Tower as A Site of Empowerment and Environment of Risk for Female Students at Bahir Dar University, Ethiopia.

Background: The poor health status of people globally is a reminder of the social gradient of health that exists within countries and between countries. Together, the structural determinants and conditions of daily life constitute the social determinants of health (SDH), and result in much of the health inequity between and within countries. In an attempt to address the SDH, and challenge the world to tackle poverty and gender inequalities in the world's poorest countries, the Millennium Development Goals (MDGs) were created. Goal three of the global Millennium Development Goals (MDGs) aims at empowering women through policies and programs that builds women's capabilities, improves their access to economic and political opportunity, and guarantees their safety. Yet, further research is needed to understand how exactly education empowers women and translates into "better lives" for women. Purpose: The overall goal is to examine how women navigate, negotiate, and mediate their sexual and reproductive health in the complex university environment. Methods: The study was cross-sectional in design and employed mixed methodology. It consisted of key informant interviews, in-depth interviews, focus group discussions, and self-administered questionnaires. Results: The case study of Ethiopia provides important lessons learned and an understanding of how to effectively implement strategies to address MDG3. Results of this study suggest that interventions should enhance women's power to make decisions and their ability to access resources. The power dynamics that continue to keep women down must be addressed to allow them the opportunity to rise to the level of their male peers

Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020

To determine possible modes of virus transmission, we investigated a cluster of coronavirus disease cases associated with a shopping mall in Wenzhou, China. Data indicated that indirect transmission of the causative virus occurred, perhaps resulting from virus contamination of common objects, virus aerosolization in a confined space, or spread from asymptomatic infected persons

Tracheal histology and short circuit current measurements.

<p>(A) AB-PAS stained tracheal sections from 6 week old rats. Submucosal glandular tissue indicated by arrowheads. Low magnification bar = 500 µm, high magnification bar = 50 µm (B & C) Summary data from Ussing chamber short circuit current measurements. Panels on right depict a modified protocol designed to specifically detect baseline (constitutive) CFTR function. (n = 3–6 animals/group) **p≤0.01, ***p≤0.001, ****p≤0.0001.</p