ДИНАМИКА ТУБЕРКУЛЕЗНОГО ПРОЦЕССА У ПАЦИЕНТОВ С РАЗЛИЧНЫМ ПСИХОЛОГИЧЕСКИМ СТАТУСОМ

The objective of the study: to investigate the changes in the course of tuberculosis in the patients with different psychological status.Subjects and methods. The changes in the course of tuberculosis were studied in 249 new pulmonary tuberculosis patients who had in-patient treatment in CTRI. The groups within the study were formed basing on the results of psychological status assessment: Group 1 included patients with favorable psychological status (171; 68.7% of patients) and Group 2 included patients with different psychological disorders (78; 31.3% of patients) (p < 0.001). Among patients from Group 2 women (66; 84.6%) significantly prevailed over men (12; 15.4%) (< 0.001).Results. It has been found out that groups with different psychological status did not confidently differ in their clinical and X-ray signs before the treatment start. Whereby, in patients from Group 2 versus patients from Group 1, the abnormalities in the results of laboratory tests were registered confidently more often (87.2 versus 75.4% cases) (p < 0.05), as well as multiple drug resistance (58 versus 41.4% of cases) (p < 0.05). The frequency of adverse events caused by anti-tuberculosis drugs was higher in Group 2 versus Group 1 (25; 32.1% and 28; 16.4% of cases) (p < 0.05). After management of adverse events, the number of patients with poor tolerance was still confidently higher in Group 2 (14; 17.9% of cases), compared to Group 1 (11; 6.4%) (p < 0.05). It was found out that the efficiency of in-patient treatment did not confidently differ in the patients with different psychological status.Цель исследования: изучение динамики туберкулезного процесса у пациентов с различным психологическим статусом.Материалы и методы. Изучена динамика туберкулезного процесса у 249 впервые выявленных пациентов, находившихся на стационарном лечении в ФГБНУ «ЦНИИТ». Группы исследования сформированы по результатам диагностики психологического статуса: 1-я группа с благоприятным психологическим статусом (171; 68,7% пациентов) и 2-я группа с различными нарушениями психологического статуса (78; 31,3% пациентов) (p < 0,001). Среди пациентов 2-й группы доля женщин (66; 84,6%) значительно преобладала по сравнению с мужчинами (12; 15,4%) (p < 0,001).Результаты. Установлено, что группы с различным психологическим статусом до начала терапии достоверно не различались по клинико-рентгенологическим проявлениям заболевания. При этом у пациентов 2-й группы по сравнению с пациентами 1-й группы достоверно чаще регистрировались отклонения лабораторных показателей от нормы (87,2 и 75,4% случаев) (p < 0,05), а также выявлялась множественная лекарственная устойчивость МБТ (58 и 41,4% случаев) (p < 0,05). Частота выявления нежелательных реакций на прием противотуберкулезных препаратов оказалась более высокой во 2-й группе по сравнению с 1-й группой (25; 32,1% и 28; 16,4% случаев) (p < 0,05). После терапевтической коррекции нежелательных реакций доля пациентов с неудовлетворительной переносимостью оставалась во 2-й группе достоверно более высокой (14; 17,9% случаев), чем в 1-й группе (11; 6,4%) (p < 0,05). Установлено, что результативность стационарного лечения достоверно не различалась среди пациентов с различным психологическим статусом

Выдающиеся деятели музыкального искусства в Красноярском крае: Владимир Александрович Аверин

Life and career development of an eminent leader of the Krasnoyarsk Territory, the honored artist of the Russian Federation Vladimir Alexandrovich Averin are studied in the article. The path of the propagandist-balalaika player, the teacher and the scientist-researcher’s becoming in the field of music is in the center of attention. The materials of the interview with V.A. Averin are provided in the article. The performer’s contribution into the cultural life of the Krasnoyarsk Territory and into the development of musical education specializing in balalaika in the territory of Eastern Siberia is analyzed. The results of pedagogical, educational and research activity are summed up.В статье рассматривается жизненный и творческий путь выдающегося деятеля Краснояр- ского края, заслуженного артиста РФ – Владимира Александровича Аверина. В центре вни- мания – путь становления пропагандиста-балалаечника, педагога, ученого-исследователя на музыкальном поприще. В статье представлены материалы интервью с В.А. Авериным. Анализируется вклад артиста в культурную жизнь Красноярского края, в развитие музыкаль- ного образования по классу балалайки на территории Восточной Сибири. Подводятся итоги педагогической, просветительской, исследовательской деятельност

Выдающиеся деятели музыкального искусства в Красноярском крае: Владимир Александрович Аверин

Life and career development of an eminent leader of the Krasnoyarsk Territory, the honored artist of the Russian Federation Vladimir Alexandrovich Averin are studied in the article. The path of the propagandist-balalaika player, the teacher and the scientist-researcher’s becoming in the field of music is in the center of attention. The materials of the interview with V.A. Averin are provided in the article. The performer’s contribution into the cultural life of the Krasnoyarsk Territory and into the development of musical education specializing in balalaika in the territory of Eastern Siberia is analyzed. The results of pedagogical, educational and research activity are summed up.В статье рассматривается жизненный и творческий путь выдающегося деятеля Краснояр- ского края, заслуженного артиста РФ – Владимира Александровича Аверина. В центре вни- мания – путь становления пропагандиста-балалаечника, педагога, ученого-исследователя на музыкальном поприще. В статье представлены материалы интервью с В.А. Авериным. Анализируется вклад артиста в культурную жизнь Красноярского края, в развитие музыкаль- ного образования по классу балалайки на территории Восточной Сибири. Подводятся итоги педагогической, просветительской, исследовательской деятельност

The Ceramic Composition Using Vermiculite

The possibility of obtaining effective wall materials and technological lightweight products for high-temperature insulation by introducing the expanded vermiculite into the ceramic mass is investigated. Mineralogy of used clays and vermiculites was studied. They are represented by minerals of the same class, and therefore weak adhesion of smooth surfaces of vermiculite grains is compensated by common genetic origin with the matrix of the basic material of the composite. Thermotechnical studies of the process of swelling of vermiculite in a quartz furnace showed that to obtain a relatively high mechanical strength of vermiculite grains, it is necessary to select the maximum temperature and the mode of swelling, so that the planar shape of vermiculite plates remains and there is no pronounced warping. The degree of thermal delamination is influenced by the particle size, the increase of which entails a deterioration in physical and mechanical properties. The introduction of a high percentage of vermiculite additives in the charge allows to obtain lightweight thermal insulation products

CHANGES IN THE COURSE OF TUBERCULOSIS IN THE PATIENTS WITH DIFFERENT PSYCHOLOGICAL STATUS

The objective of the study: to investigate the changes in the course of tuberculosis in the patients with different psychological status.Subjects and methods. The changes in the course of tuberculosis were studied in 249 new pulmonary tuberculosis patients who had in-patient treatment in CTRI. The groups within the study were formed basing on the results of psychological status assessment: Group 1 included patients with favorable psychological status (171; 68.7% of patients) and Group 2 included patients with different psychological disorders (78; 31.3% of patients) (p < 0.001). Among patients from Group 2 women (66; 84.6%) significantly prevailed over men (12; 15.4%) (< 0.001).Results. It has been found out that groups with different psychological status did not confidently differ in their clinical and X-ray signs before the treatment start. Whereby, in patients from Group 2 versus patients from Group 1, the abnormalities in the results of laboratory tests were registered confidently more often (87.2 versus 75.4% cases) (p < 0.05), as well as multiple drug resistance (58 versus 41.4% of cases) (p < 0.05). The frequency of adverse events caused by anti-tuberculosis drugs was higher in Group 2 versus Group 1 (25; 32.1% and 28; 16.4% of cases) (p < 0.05). After management of adverse events, the number of patients with poor tolerance was still confidently higher in Group 2 (14; 17.9% of cases), compared to Group 1 (11; 6.4%) (p < 0.05). It was found out that the efficiency of in-patient treatment did not confidently differ in the patients with different psychological status

Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan

Noda, Maiko, Oshida, Tatsuo, Abramov, Alexei V., Baranova, Galina, Baryshinikov, Gennady, Ichikawa, Hideo, Masuda, Ryuichi (2015): Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan. Journal of Natural History 50: 771-786, DOI: 10.1080/00222933.2015.1083056, URL: http://dx.doi.org/10.1080/00222933.2015.108305

Figure 1 in Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan

Figure 1. Vegetation zones in Hokkaido Island, Japan: A) present; B) during the last glacial period (after Dobson 1994).Published as part of Noda, Maiko, Oshida, Tatsuo, Abramov, Alexei V., Baranova, Galina, Baryshinikov, Gennady, Ichikawa, Hideo & Masuda, Ryuichi, 2015, Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan, pp. 771-786 in Journal of Natural History 50 on page 772, DOI: 10.1080/00222933.2015.1083056, http://zenodo.org/record/398977

Figure 5 in Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan

Figure 5. Observed (solid lines with solid diamonds) and expected (dotted lines with open squares) mismatch distributions of Sciurus vulgaris orientis haplotypes: A) northern population; B) southern population; C) over all of Hokkaido population.Published as part of Noda, Maiko, Oshida, Tatsuo, Abramov, Alexei V., Baranova, Galina, Baryshinikov, Gennady, Ichikawa, Hideo & Masuda, Ryuichi, 2015, Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan, pp. 771-786 in Journal of Natural History 50 on page 781, DOI: 10.1080/00222933.2015.1083056, http://zenodo.org/record/398977

Figure 4 in Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan

Figure 4. Network of the 29 cytochrome b gene haplotypes of Sciurus vulgaris orientis in Hokkaido Island, Japan, using statistical parsimony. Haplotype names correspond to Appendix 1. Missing haplotypes are indicated by open circles. Lines connecting haplotypes indicate the relationship. Numbers in parentheses indicate the number of individuals. Haplotypes without parentheses are from just one individual.Published as part of Noda, Maiko, Oshida, Tatsuo, Abramov, Alexei V., Baranova, Galina, Baryshinikov, Gennady, Ichikawa, Hideo & Masuda, Ryuichi, 2015, Phylogeography of the Eurasian red squirrel (Sciurus vulgaris orientis) on the boreal island of Hokkaido, Japan, pp. 771-786 in Journal of Natural History 50 on page 779, DOI: 10.1080/00222933.2015.1083056, http://zenodo.org/record/398977

Expression of Cytochrome c3 from Desulfovibrio vulgaris in Plant Leaves Enhances Uranium Uptake and Tolerance of Tobacco

Cytochrome c3 (uranyl reductase) from Desulfovibrio vulgaris can reduce uranium in bacterial cells and in cell-free systems. This gene was introduced in tobacco under control of the RbcS promoter, and the resulting transgenic plants accumulated uranium when grown on a uranyl ion containing medium. The uptaken uranium was detected by EM in chloroplasts. In the presence of uranyl ions in sublethal concentration, the transgenic plants grew phenotypically normal while the control plants’ development was impaired. The data on uranium oxidation state in the transgenic plants and the possible uses of uranium hyperaccumulation by plants for environmental cleanup are discussed