283 research outputs found
An evaluation framework for input variable selection algorithms for environmental data-driven models
Abstract not availableStefano Galelli, Greer B. Humphrey, Holger R. Maier, Andrea Castelletti, Graeme C. Dandy, Matthew S. Gibb
Mechanisms of escape phenomenon of spinal cord and brainstem in human rabies
BACKGROUND: Rabies virus preferentially involves brainstem, thalamus and spinal cord in human furious and paralytic rabies beginning in the early stage of illness. Nevertheless, rabies patient remains alert until the pre-terminal phase. Weakness of extremities develops only when furious rabies patient becomes comatose; whereas peripheral nerve dysfunction is responsible for weakness in paralytic rabies. METHODS: Evidence of apoptosis and mitochondrial outer membrane permeabilization in brain and spinal cord of 10 rabies patients was examined and these findings were correlated with the presence of rabies virus antigen. RESULTS: Although apoptosis was evident in most of the regions, cytochrome c leakage was relatively absent in spinal cord of nearly all patients despite the abundant presence of rabies virus antigen. Such finding was also noted in brainstem of 5 patients. CONCLUSION: Cell death in human rabies may be delayed in spinal cord and the reticular activating system, such as brainstem, thus explaining absence of weakness due to spinal cord dysfunction and preservation of consciousness
A Search for Photons with Energies Above 2 × 10 eV Using Hybrid Data from the Low-Energy Extensions of the Pierre Auger Observatory
Ultra-high-energy photons with energies exceeding 10 eV offer a wealth of connections to different aspects of cosmic-ray astrophysics as well as to gamma-ray and neutrino astronomy. The recent observations of photons with energies in the 10 eV range further motivate searches for even higher-energy photons. In this paper, we present a search for photons with energies exceeding 2 × 10 eV using about 5.5 yr of hybrid data from the low-energy extensions of the Pierre Auger Observatory. The upper limits on the integral photon flux derived here are the most stringent ones to date in the energy region between 10 and 10 eV
The Pierre Auger Observatory Open Data
The Pierre Auger Collaboration has embraced the concept of open access to
their research data since its foundation, with the aim of giving access to the
widest possible community. A gradual process of release began as early as 2007
when 1% of the cosmic-ray data was made public, along with 100% of the
space-weather information. In February 2021, a portal was released containing
10% of cosmic-ray data collected from 2004 to 2018, during Phase I of the
Observatory. The Portal included detailed documentation about the detection and
reconstruction procedures, analysis codes that can be easily used and modified
and, additionally, visualization tools. Since then the Portal has been updated
and extended. In 2023, a catalog of the 100 highest-energy cosmic-ray events
examined in depth has been included. A specific section dedicated to
educational use has been developed with the expectation that these data will be
explored by a wide and diverse community including professional and
citizen-scientists, and used for educational and outreach initiatives. This
paper describes the context, the spirit and the technical implementation of the
release of data by the largest cosmic-ray detector ever built, and anticipates
its future developments.Comment: 19 pages, 8 figure
A Search for Photons with Energies above 2 × 1017eV Using Hybrid Data from the Low-Energy Extensions of the Pierre Auger Observatory
Ultra-high-energy photons with energies exceeding 1017 eV offer a wealth of connections to different aspects of cosmic-ray astrophysics as well as to gamma-ray and neutrino astronomy. The recent observations of photons with energies in the 1015 eV range further motivate searches for even higher-energy photons. In this paper, we present a search for photons with energies exceeding 2 × 1017 eV using about 5.5 yr of hybrid data from the low-energy extensions of the Pierre Auger Observatory. The upper limits on the integral photon flux derived here are the most stringent ones to date in the energy region between 1017 and 1018 eV
Radio Measurements of the Depth of Air-Shower Maximum at the Pierre Auger Observatory
The Auger Engineering Radio Array (AERA), part of the Pierre Auger
Observatory, is currently the largest array of radio antenna stations deployed
for the detection of cosmic rays, spanning an area of km with 153
radio stations. It detects the radio emission of extensive air showers produced
by cosmic rays in the MHz band. Here, we report the AERA measurements
of the depth of the shower maximum (), a probe for mass
composition, at cosmic-ray energies between to eV,
which show agreement with earlier measurements with the fluorescence technique
at the Pierre Auger Observatory. We show advancements in the method for radio
reconstruction by comparison to dedicated sets of CORSIKA/CoREAS
air-shower simulations, including steps of reconstruction-bias identification
and correction, which is of particular importance for irregular or sparse radio
arrays. Using the largest set of radio air-shower measurements to date, we show
the radio resolution as a function of energy, reaching a
resolution better than g cm at the highest energies, demonstrating
that radio measurements are competitive with the established
high-precision fluorescence technique. In addition, we developed a procedure
for performing an extensive data-driven study of systematic uncertainties,
including the effects of acceptance bias, reconstruction bias, and the
investigation of possible residual biases. These results have been
cross-checked with air showers measured independently with both the radio and
fluorescence techniques, a setup unique to the Pierre Auger Observatory.Comment: Submitted to Phys. Rev.
Demonstrating Agreement between Radio and Fluorescence Measurements of the Depth of Maximum of Extensive Air Showers at the Pierre Auger Observatory
We show, for the first time, radio measurements of the depth of shower
maximum () of air showers induced by cosmic rays that are
compared to measurements of the established fluorescence method at the same
location. Using measurements at the Pierre Auger Observatory we show full
compatibility between our radio and the previously published fluorescence data
set, and between a subset of air showers observed simultaneously with both
radio and fluorescence techniques, a measurement setup unique to the Pierre
Auger Observatory. Furthermore, we show radio resolution as a
function of energy and demonstrate the ability to make competitive
high-resolution measurements with even a sparse radio array.
With this, we show that the radio technique is capable of cosmic-ray mass
composition studies, both at Auger and at other experiments.Comment: Submitted to Phys. Rev. Let
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