Measurement of the B --> K^* gamma Branching Fractions and Asymmetries

We report measurements of the radiative decay B --> K^*\gamma. The analysis is based on a data sample containing 85.0*10^6 B meson pairs collected by the Belle detector at the KEKB storage ring. We measure branching fractions of Br(B^0 --> K^{*0}\gamma) = (4.01 \pm 0.21 \pm 0.17)*10^{-5} and Br(B^+ --> K^{*+}\gamma) = (4.25 \pm 0.31 \pm 0.24)*10^{-5}, where the first and second errors are statistical and systematic, respectively. The isospin asymmetry between B^0 and B^+ decay widths is measured to be \Delta_{0+} = +0.012 \pm 0.044 \pm 0.026. We search for a partial rate asymmetry between CP conjugate modes, and find A_{cp}(B --> K^*\gamma) = =0.015 \pm 0.044 \pm 0.012.Comment: 10 pages, 5 figures, submitted to Phys. Rev.

Measurement of the Branching Fractions for B→ωKB \to \omega K and B→ωπB \to \omega \pi

We report improved measurements of branching fractions for charmless hadronic two-body {\it B} meson decays containing an $\omega$ meson in the final state. The results are based on a data sample of 78 fb$^{-1}$ collected on the $\Upsilon(4S)$ resonance by the Belle detector. We measure the branching fractions ${\mathcal B}(B^+ \to \omega K^+) = (6.5^{+1.3}_{-1.2}\pm 0.6)\times 10^{-6}$ and ${\mathcal B}(B^+ \to \omega \pi^+) = (5.7^{+1.4}_{-1.3}\pm 0.6)\times 10^{-6}.$ We give 90% confidence upper limits for ${\mathcal B}(B^0 \to \omega K^0) < 7.6\times 10^{-6}$ and ${\mathcal B}(B^0 \to \omega \pi^0) < 1.9\times 10^{-6}.$ We also obtain the partial rate asymmetries ${\mathcal A}_{CP}=0.06^{+0.21}_{-0.18}\pm 0.01$ for $B^\pm \to \omega K^\pm$ and ${\mathcal A}_{CP}=0.50^{+0.23}_{-0.20}\pm 0.02$ for $B^\pm \to \omega \pi^\pm.$Comment: 7 pages, 4 figures, tar.gz files submitted to PR

Draft Genome Sequence of Streptococcus suis S10, a Virulent Strain Used in Experimental Pig Infections

Here, we report the draft whole-genome sequence of Streptococcus suis strain S10, isolated from the tonsils of a healthy pig. S. suis S10 belongs to the highly virulent serotype 2, which includes isolates that cause infectious diseases, including meningitis, in pigs and human. The genome contains a complete prophage that encodes a candidate virulence gene

Draft Genome Sequence of Streptococcus suis S10, a Virulent Strain Used in Experimental Pig Infections

Here, we report the draft whole-genome sequence of Streptococcus suis strain S10, isolated from the tonsils of a healthy pig. S. suis S10 belongs to the highly virulent serotype 2, which includes isolates that cause infectious diseases, including meningitis, in pigs and human. The genome contains a complete prophage that encodes a candidate virulence gene

Rothia nasimurium strain:PT-32 Genome sequencing and assembly

Streptococcus suis is an important porcine and zoonotic pathogen for which there is no effective cross-protective vaccine. S. suis is the cause of significant economic losses to the pig production industry worldwide, and there is a need for alternative strategies to prevent colonization and invasive disease, especially in young pigs. We have explored the microbiota of healthy piglets with the aim to find commensal bacteria that can specifically kill or inhibit the growth of S. suis. Here we describe the identification and characterization of a commensal Rothia nasimurium strain from the porcine palatine tonsil that effectively inhibits a wide range of S. suis strains in vitro

Selection of antimicrobial frog peptides and temporin-1DRa analogues for treatment of bacterial infections based on their cytotoxicity and differential activity against pathogens

Cationic, amphipathic, α‐helical host‐defense peptides (HDPs) that are naturally secreted by certain species of frogs (Anura) possess potent broad‐spectrum antimicrobial activity and show therapeutic potential as alternatives to treat infections by multi‐drug resistant pathogens. Fourteen amphibian skin peptides and twelve analogues of temporin‐1DRa were studied for their antimicrobial activities against clinically relevant human or animal skin infection‐associated pathogens. For comparison, antimicrobial potencies of frog skin peptides against a range of probiotic lactobacilli were determined. We used the VITEK 2 system to define a profile of antibiotic susceptibility for the bacterial panel. The minimal inhibitory concentration (MIC) values of the naturally occurring temporin‐1DRa, CPF‐AM1, alyteserin‐1c, hymenochirin‐2B, and hymenochirin‐4B for pathogenic bacteria were 3‐ to 9‐fold lower than the values for the tested probiotic strains. Similarly, temporin‐1DRa and its [Lys4], [Lys5] and [Aib8] analogues showed 5‐ to 6.5‐fold greater potency against the pathogens. In the case of PGLa‐AM1, XT‐7, temporin‐1DRa and its [D‐Lys8] and [Aib13] analogues, no apoptosis or necrosis was detected in human peripheral blood mononuclear cells at concentrations below or above the MIC. Given the differential activity against commensal bacteria and pathogens, some of these peptides are promising candidates for further development into therapeutics for topical treatment of skin infection

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