164 research outputs found
Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study
Characterisation of a Thin Fully Depleted SOI Pixel Sensor with High Momentum Charged Particles
This paper presents the results of the characterisation of a thin, fully
depleted pixel sensor manufactured in SOI technology on high-resistivity
substrate with high momentum charged particles. The sensor is thinned to 70
m and a thin phosphor layer contact is implanted on the back-plane. Its
response is compared to that of thick sensors of same design in terms of signal
and noise, detection efficiency and single point resolution based on data
collected with 300 GeV pions at the CERN SPS. We observe that the charge
collected and the signal-to-noise ratio scale according to the estimated
thickness of the sensitive volume and the efficiency and single point
resolution of the thinned chip are comparable to those measured for the thick
sensors.Comment: 8 pages, 3 figures, submitted to Nucl. Instr. and Meth., section
a previously undescribed entity
Background: There are few studies describing periodic limb movement syndrome
(PLMS) in rapid eye movement (REM) sleep in patients with narcolepsy, restless
legs syndrome, REM sleep behavior disorder, and spinal cord injury, and to a
lesser extent, in insomnia patients and healthy controls, but no published
cases in multiple sclerosis (MS). The aim of this study was to investigate
PLMS in REM sleep in MS and to analyze whether it is associated with age, sex,
disability, and laboratory findings. Methods: From a study of MS patients
originally published in 2011, we retrospectively analyzed periodic limb
movements (PLMs) during REM sleep by classifying patients into two subgroups:
PLM during REM sleep greater than or equal to ten per hour of REM sleep (n=7)
vs less than ten per hour of REM sleep (n=59). A univariate analysis between
PLM and disability, age, sex, laboratory findings, and polysomnographic data
was performed. Results: MS patients with more than ten PLMs per hour of REM
sleep showed a significantly higher disability measured by the Kurtzke
expanded disability status scale (EDSS) (P=0.023). The presence of more than
ten PLMs per hour of REM sleep was associated with a greater likelihood of
disability (odds ratio 22.1; 95% confidence interval 3.5–139.7; P<0.0001),
whereas there were no differences in laboratory and other polysomnographic
findings. Conclusion: PLMs during REM sleep were not described in MS earlier,
and they are associated with disability measured by the EDSS
Monolithic Pixel Sensors in Deep-Submicron SOI Technology with Analog and Digital Pixels
This paper presents the design and test results of a prototype monolithic
pixel sensor manufactured in deep-submicron fully-depleted Silicon-On-Insulator
(SOI) CMOS technology. In the SOI technology, a thin layer of integrated
electronics is insulated from a (high-resistivity) silicon substrate by a
buried oxide. Vias etched through the oxide allow to contact the substrate from
the electronics layer, so that pixel implants can be created and a reverse bias
can be applied. The prototype chip, manufactured in OKI 0.15 micron SOI
process, features both analog and digital pixels on a 10 micron pitch. Results
of tests performed with infrared laser and 1.35 GeV electrons and a first
assessment of the effect of ionising and non-ionising doses are discussed.Comment: 5 pages, 7 figures, submitted to Nuclear Instruments and Methods
Interventions involving own treatment choice for people living with coexisting severe mental illness and type 1 or 2 diabetes:A scoping review
New Angles on Fast Calorimeter Shower Simulation
The demands placed on computational resources by the simulation requirements
of high energy physics experiments motivate the development of novel simulation
tools. Machine learning based generative models offer a solution that is both
fast and accurate. In this work we extend the Bounded Information Bottleneck
Autoencoder (BIB-AE) architecture, designed for the simulation of particle
showers in highly granular calorimeters, in two key directions. First, we
generalise the model to a multi-parameter conditioning scenario, while
retaining a high degree of physics fidelity. In a second step, we perform a
detailed study of the effect of applying a state-of-the-art particle flow-based
reconstruction procedure to the generated showers. We demonstrate that the
performance of the model remains high after reconstruction. These results are
an important step towards creating a more general simulation tool, where
maintaining physics performance after reconstruction is the ultimate target.Comment: 26 pages, 19 figure
Radio Galaxy Classification with wGAN-Supported Augmentation
Novel techniques are indispensable to process the flood of data from the new
generation of radio telescopes. In particular, the classification of
astronomical sources in images is challenging. Morphological classification of
radio galaxies could be automated with deep learning models that require large
sets of labelled training data. Here, we demonstrate the use of generative
models, specifically Wasserstein GANs (wGAN), to generate artificial data for
different classes of radio galaxies. Subsequently, we augment the training data
with images from our wGAN. We find that a simple fully-connected neural network
for classification can be improved significantly by including generated images
into the training set.Comment: 10 pages, 6 figures; accepted to ml.astro; v2: matches published
versio
Studies of Vertex Tracking with SOI Pixel Sensors for Future Lepton Colliders
This paper presents a study of vertex tracking with a beam hodoscope
consisting of three layers of monolithic pixel sensors in SOI technology on
high-resistivity substrate. We study the track extrapolation accuracy,
two-track separation and vertex reconstruction accuracy in pion-Cu interactions
with 150 and 300 GeV/c pions at the CERN SPS. Results are discussed in the
context of vertex tracking at future lepton colliders.Comment: 15 pages, 8 figures, submitted to Nuclear Instruments and Methods
Bridging Alone: Religious Conservatism, Marital Homogamy, and Voluntary Association Membership
This study characterizes social insularity of religiously conservative American married couples by examining patterns of voluntary associationmembership. Constructing a dataset of 3938 marital dyads from the second wave of the National Survey of Families and Households, the author investigates whether conservative religious homogamy encourages membership in religious voluntary groups and discourages membership in secular voluntary groups. Results indicate that couples’ shared affiliation with conservative denominations, paired with beliefs in biblical authority and inerrancy, increases the likelihood of religious group membership for husbands and wives and reduces the likelihood of secular group membership for wives, but not for husbands. The social insularity of conservative religious groups appears to be reinforced by homogamy—particularly by wives who share faith with husbands
Multi-Jet Event Rates in Deep Inelastic Scattering and Determination of the Strong Coupling Constant
Jet event rates in deep inelastic ep scattering at HERA are investigated
applying the modified JADE jet algorithm. The analysis uses data taken with the
H1 detector in 1994 and 1995. The data are corrected for detector and
hadronization effects and then compared with perturbative QCD predictions using
next-to-leading order calculations. The strong coupling constant alpha_S(M_Z^2)
is determined evaluating the jet event rates. Values of alpha_S(Q^2) are
extracted in four different bins of the negative squared momentum
transfer~\qq in the range from 40 GeV2 to 4000 GeV2. A combined fit of the
renormalization group equation to these several alpha_S(Q^2) values results in
alpha_S(M_Z^2) = 0.117+-0.003(stat)+0.009-0.013(syst)+0.006(jet algorithm).Comment: 17 pages, 4 figures, 3 tables, this version to appear in Eur. Phys.
J.; it replaces first posted hep-ex/9807019 which had incorrect figure 4
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