2,256 research outputs found
Total Nuclear Reaction Cross Section Induced by Halo Nuclei and Stable Nuclei
We develop the method for the calculation of the total reaction cross
sections induced by the halo nuclei and stable nuclei. This approach is based
on the Glauber theory, which is valid for nuclear reactions at high energy. It
is extended for nuclear reactions at low energy and intermediate energy by
including both the quantum correction and Coulomb correction under the
assumption of the effective nuclear density distribution. The calculated
results of the total reaction cross section induced by stable nuclei agree well
with the 30 experimental data within 10 percent accuracy.The comparison between
the numerical results and the 20 experimental data for the total nuclear
reaction cross section induced by the neutron halo nuclei and the proton halo
nuclei indicates a satisfactory agreement after considering the halo structure
of these nuclei, which implies the quite different mean fields for the nuclear
reactions induced by halo nuclei and stable nuclei. The halo nucleon
distributions and the root mean square radii of these nuclei can be extracted
from above comparison based on the improved Glauber model, which indicate
clearly the halo structures of these nuclei. Especially, it is clear to see
that the medium correction of the nucleon-nucleon collision has little effect
on the total reaction cross sections induced by the halo nuclei due to the very
weak binding and the very extended density distribution.Comment: 15 pages,2 figures. Communucations in Theoretical Physics, (2003) in
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Statistical Assessment of the Global Regulatory Role of Histone Acetylation in Saccharomyces cerevisiae
BACKGROUND: Histone acetylation plays important but incompletely understood roles in gene regulation. A comprehensive understanding of the regulatory role of histone acetylation is difficult because many different histone acetylation patterns exist and their effects are confounded by other factors, such as the transcription factor binding sequence motif information and nucleosome occupancy.
RESULTS: We analyzed recent genomewide histone acetylation data using a few complementary statistical models and tested the validity of a cumulative model in approximating the global regulatory effect of histone acetylation. Confounding effects due to transcription factor binding sequence information were estimated by using two independent motif-based algorithms followed by a variable selection method. We found that the sequence information has a significant role in regulating transcription, and we also found a clear additional histone acetylation effect. Our model fits well with observed genome-wide data. Strikingly, including more complicated combinatorial effects does not improve the model's performance. Through a statistical analysis of conditional independence, we found that H4 acetylation may not have significant direct impact on global gene expression.
CONCLUSION: Decoding the combinatorial complexity of histone modification requires not only new data but also new methods to analyze the data. Our statistical analysis confirms that histone acetylation has a significant effect on gene transcription rates in addition to that attributable to upstream sequence motifs. Our analysis also suggests that a cumulative effect model for global histone acetylation is justified, although a more complex histone code may be important at specific gene loci. We also found that the regulatory roles among different histone acetylation sites have important differences.Statistic
Experimental Observation of Classical Sub-Wavelength Interference with Thermal-Like Light
We show the experimental observation of the classical sub-wavelength
double-slit interference with a pseudo-thermal light source. The experimental
results are in agreement with the recent theoretical prediction shown in
quant-ph/0404078 (to be appeared in Phys. Rev. A).Comment: 4 pages, 6 figure
Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF.
Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of cancer cell growth. Numerous animal models demonstrated its therapeutic value in treating blinding diseases and diverse cancer types. A long-standing challenge is to reveal how PEDF acts on its target cells and the identities of the cell-surface receptors responsible for its activities. Here we report the identification of transmembrane proteins PLXDC1 and PLXDC2 as cell-surface receptors for PEDF. Using distinct cellular models, we demonstrate their cell type-specific receptor activities through loss of function and gain of function studies. Our experiments suggest that PEDF receptors form homooligomers under basal conditions, and PEDF dissociates the homooligomer to activate the receptors. Mutations in the intracellular domain can have profound effects on receptor activities
The Study of the Composite Material Go/CF/PTFE Tribological Property
In this paper, the composite material Go/CF/PTFE tribological property was studied. The test of its mechanical property, and the fabrication of the filled PTEE composite material sample which is based on the technology of cold press molding and sinter molding proved that adding Go and CF moderately to the composite material was an efficient way to improve its mechanical property. Meanwhile the process of friction and wear trial and SEM analysis results of the micro-structure of wear pattern proved that the addition of the Go and CF tremendously improved the anti-wear property and that after the addition the plowing effect which took place on the material surface would turn into a kind of mixed wear effect that includes plowing effect and fatigue wear. Working as pinning and bridging, the Go which distributing uniformly in the matrix was able to improve the resistance and substantially resisted the crack propagation, therefore to a certain degree enhanced the intensity of composite material and prolong its lifespan
Imaging and spectral study on the null point of a fan-spine structure during a solar flare
Using the multi-instrument observations, we make the first simultaneous
imaging and spectral study on the null point of a fan-spine magnetic topology
during a solar flare. When magnetic reconnection occurs at the null point, the
fan-spine configuration brightens in the (extreme-)ultraviolet channels. In the
H images, the fan-spine structure is partly filled and outlined by the
bi-directional material flows ejected from the reconnection site. The
extrapolated coronal magnetic field confirms the existence of the fan-spine
topology. Before and after the flare peak, the total velocity of the outflows
is estimated to be about 60 km s. During the flare, the Si IV line
profile at the reconnection region is enhanced both in the blue-wing and
red-wing. At the flare peak time, the total velocity of the outflows is found
to be 144 km s. Superposed on the Si IV profile, there are several deep
absorption lines with the blueshift of several tens of km s. The reason
is inferred to be that the bright reconnection region observed in Si IV channel
is located under the cooler material appearing as dark features in the
H line. The blueshifted absorption lines indicate the movement of the
cooler material toward the observer. The depth of the absorption lines also
depends on the amount of cooler material. These results imply that this kind of
spectral profiles can be used as a tool to diagnose the properties of cooler
material above reconnection site.Comment: Accepted for publication in Ap
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