Inclusion in physical education for students with severe disabilities

This qualitative case study investigated the effectiveness of inclusive physical education for two third grade students with severe disabilities utilizing a social constructionist framework. In the first class, one student was identified as having significant language based challenges. The second class included a child with severe cerebral palsy. Four levels of relations were identified: systemic relations, group relations, conjoint relations and internal others. Each focused on specific areas within the school and the classroom that contributed to the construction of disability. Data were collected from three primary sources: interviews, participant-observer, and document review. Boyzaitis\u27s (1998) five-step process was utilized in the data analysis through the constant comparative method of coding the multiple data sources in developing the emerging theory (Merriam, 1998; Strauss & Corbin, 1998). At the systemic level, administrators expressed views of disability and displayed practices grounded in the legal changes of PL94-142 and ensuing processes that occurred as students with disabilities were integrated into the public schools. Teachers and paraprofessionals within the group relations of the classroom expressed social, environmental, and academic constructions of disability. Students\u27 constructions of disability were conditioned by group membership, adaptations and accommodations, and their ability to successfully complete the learning tasks. The physical education teacher\u27s construction of disability was grounded in her sensitivity to difference and an ability to make learning accessible for her students with disabilities. As a theoretical framework, social construction refocused disability in the inclusive setting as a process of active engagement through forms of teacher and classroom relatedness (Kozub, Sherblom, Perry, 1999). This perspective provided an alternative to the individualistic discourse of difference embedded in special education to accommodate the challenges of the inclusive classroom. In the physical education setting, this emerged as the students in relation to their peers and teachers, the curriculum, and instructional methods

Quel avenir pour la filière porcine au lac Alaotra (Madagascar)?

Depuis l'introduction du virus de la Peste Porcine Africaine en 1997, l'élevage porcin malgache traverse une période de crise, qui tarde à être résolue. La relance de la filière est vivement souhaitée, notamment dans la région du lac Alaotra qui était un important bassin de production avant l'épizootie. Un diagnostic de la situation y a donc été réalisé afin d'évaluer la pertinence de cette relance (analyse de la filière et enquête épidémiologique sur les pestes porcines). Les résultats obtenus mettent en évidence un faible taux de prévalence de la Peste Porcine Classique (en dépit d'un faible taux d'immunisation), alors que celui de la PPA est en faveur d'une circulation importante du virus, accentuée par de nombreuses pratiques d'élevage à risque. Malgré l'absence de données nouvelles sur l'implication des deux réservoirs sauvages du virus (tique et potamochère) dans l'épidémiologie de la PPA au lac Alaotra, la relance de la filière ne paraît pas envisageable à l'heure actuelle

Description technico-économique de procédés de production du carbure de silicium (SiC)

Description des céramiques -- Applications industrielles des céramiques -- Procédés de fabrication de la céramique -- La production du carbure de silicium par le procédé Acheson -- Production du carbure de silicium par de nouveaux procédés de synthèse -- Avantages et recommandations propres à chacun des procédés

The development of an abbreviated form of the college women\u27s assertion sample.

In recent years, assertion training programs have become increasingly more popular and widespread. The value of this type of intervention has been demonstrated in the treatment of both clinical and nonclinical populations (cf. Wienman, Gelbart, Wallace and Post, 1972; Bloomfield, 1 973; Alberti and Emmons, 1 978). In response to the growing awareness of the importance of asserti veness in successful daily functioning, several measures of this characteristic have been developed (cf. McFall and Lillesand, 1971; Rathus, 1973). Most of these measures are self report questionnaires requiring written responses. For example, the Rathus Assertiveness Schedule consists of 30 statements and the subject is asked to indicate how characteristic each one is of her typical behavior. A global score reflecting one\u27s degree of assertive behavior is then derived

Étude de l’immunité antivaricelleuse chez l’enfant transplanté au moyen de moelle osseuse ou de sang de cordon ombilical

L’infection primaire au VZV et la réactivation du VZV latent sont fréquemment observées à la suite d’une GMO ou d’une GSCO, ce qui cause de sérieuses complications chez le patient. Pour prévenir ces infections, une prophylaxie antivirale est administrée systématiquement chez tous les greffés de MO ou de SCO, alors qu’il n’existe aucun consensus sur la durée optimale d’une telle prophylaxie. Pour résoudre ce problème, notre objectif est de développer et valider une méthode ELISpot-VZV-IFN- qui permettra de suivre la reconstitution de l’immunité à médiation cellulaire anti-VZV chez les receveurs de GMO ou de GSCO et ainsi déterminer le moment opportun pour réduire ou interrompe la prophylaxie chez les receveurs de greffes de CSH. Dans un premier temps, des valeurs-seuil de la réponse à médiation cellulaire anti-VZV chez la population pédiatrique saine ont dû être générées. À la lumière de nos résultats, un enfant avec un résultat ELISpot-VZV-IFN- > 190.0 SFU/106 PBMC devrait être protégé contre une possible infection à VZV. Pour valider cette étude, une étude prospective de la reconstitution immunitaire anti-VZV a été effectuée chez 9 enfants greffés de MO ou de SCO. Nos résultats préliminaires ont montré qu’il n’y avait eu aucune reconstitution significative de l’immunité à médiation cellulaire anti-VZV dans les 18 premiers mois post-transplantation chez 8 de ces 9 enfants. Les résultats de ces expériences vont fournir d’importantes informations quant à la reconstitution de l’immunité anti-VZV à la suite d’une GMO ou d’une GSCO et pourraient permettre l’amélioration des soins apportés aux receveurs de GMO ou de GSCO.Primary infection with VZV and reactivation of latent VZV are commonly observed following BMT and UCBT, leading to serious complications in patients. As a result, antiviral prophylaxis is systematically administered to BMT and UCBT recipients, yet there is no consensus that defines its optimal duration. To resolve this problem, our objective was to develop and validate a VZV-IFN--ELISpot with which reconstitution of VZV immunity can be followed in BMT and UCBT recipients, providing clinicians a practical tool to gauge the need for and adjust antiviral prophylaxis in individual HSCT recipients. First of all, threshold values for anti-VZV immunity in healthy pediatric subjects were generated. Based on our results, a child exhibiting > 190.0 VZV-specific SFU /106 PBMC should be protected against a possible VZV infection. To validate these results, a prospective study on the recovery of VZV-specific T cell immunity was performed on 9 children following BMT or UCBT. Preliminary results demonstrated that there was no significant recovery of VZV-specific T cell immunity in the first 18 months post-transplantation in 8 of 9 cases. Results of these experiments will yield important new information regarding reconstitution of anti-VZV immunity following BMT and UCBT and could lead to improvements in clinical management of BMT and UCBT recipients

Le couronnement des vierges : l'autobiographie épuisée par le motif décoratif narratif

La tapisserie narrative est le langage nouveau qui est né du besoin de poursuivre une démarche autobiographique. Mes tapisseries sont des actes d’amour à distance du corps et de la tête pensante du sujet qui est représenté. Elles sont le souvenir de celui qui n’est plus, le souvenir d’une vie terminée. La mort est passée, mais la mémoire permet aux souvenirs de rester actifs à travers une œuvre. Dans le cas qui nous occupe, une couronne de motifs peints. J’ai voulu que l’exposition Le Couronnement des vierges soit une trace visuelle et sonore de mes souvenirs. J’en fais le récit, celui de ce parcours de création nourri par le Moyen Âge, donc celui de l’autobiographie épuisée jusqu’à en faire des couronnes de motifs décoratifs. Ce texte accompagne l’exposition Le Couronnement des vierges tout d’abord présentée à Espace Projet art contemporain + design à Montréal du 5 octobre au 21 octobre 2012 et ensuite à La Chambre blanche en janvier 2013

The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids

Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and exert their effects through mechanisms involving disruption of sphingolipid metabolism.Fumonisin B1 (FB1) is the predominant fumonisins in this family. FB1 is converted to its hydrolyzed analogs HFB1, by alkaline cooking (nixtamalization) or through enzymatic degradation. The toxicity of HFB1 is poorly documented especially at the intestinal level. The objectives of this study were to compare the toxicity of HFB1 and FB1 and to assess the ability of these toxins to disrupt sphingolipids biosynthesis. HFB1 was obtained by a deesterification of FB1, with a carboxylesterase. Piglets, animals highly sensitive to FB1, were exposed by gavage for 2 weeks to 2.8 µmol FB1 or HFB1/kg body weight/day. FB1 induced hepatotoxicity as indicated by the lesion score, the level of several biochemical analytes and the expression of inflammatory cytokines. Similarly, FB1 impaired the morphology of the different section of the small intestine, reduced villi height and modified intestinal cytokine expression. By contrast, HFB1 did not trigger hepatotoxicity, did not impair intestinal morphology and slightly modified the intestinal immune response. This low toxicity of HFB1 correlates with a weak alteration of the sphinganine/sphingosine ratio in the liver and in the plasma. Taken together, these data demonstrate that HFB1 does not cause intestinal or hepatic toxicity in the sensitive pig model, and slightly disrupts sphingolipids metabolism. This finding suggests that conversion to HFB1 could be a good strategy to reduce FB1 exposure

Omental adipocyte hypertrophy relates to coenzyme Q10 redox state and lipid peroxidation in obese women

Occurrence of oxidative stress in white adipose tissues contributes to its dysfunction and the development of obesity-related metabolic complications. Coenzyme Q10 (CoQ10) is the single lipophilic antioxidant synthesized in humans and is essential for electron transport during mitochondrial respiration. To understand the role of CoQ10 in adipose tissue physiology and dysfunction, the abundance of the oxidized and reduced (CoQ10red) isoforms of the CoQ10 were quantified in subcutaneous and omental adipose tissues of women covering the full range of BMI (from 21.5 to 53.2 kg/m2). Lean women displayed regional variations of CoQ10 redox state between the omental and subcutaneous depot, despite similar total content. Obese women had reduced CoQ10red concentrations in the omental depot, leading to increased CoQ10 redox state and higher levels of lipid hydroperoxide. Women with low omental CoQ10 content had greater visceral and subcutaneous adiposity, increased omental adipocyte diameter, and higher circulating interleukin-6 and C-reactive protein levels and were more insulin resistant. The associations between abdominal obesity-related cardiometabolic risk factors and CoQ10 content in the omental depot were abolished after adjustment for omental adipocyte diameter. This study shows that hypertrophic remodeling of visceral fat closely relates to depletion of CoQ10, lipid peroxidation, and inflammation

Strain driven monoclinic distortion of ultrathin CoO films in the exchange-coupled CoO/FePt/Pt(001) system

International audienceThe structure and strain of ultrathin CoO films grown on a Pt(001) substrate and on a ferro-magnetic FePt pseudomorphic layer on Pt(001) have been determined with insitu and real time surface x-ray diffraction. The films grow epitaxially on both surfaces with an in-plane hexagonal pattern that yields a pseudo-cubic CoO(111) surface. A refined x-ray diffraction analysis reveals a slight monoclinic distortion at RT induced by the anisotropic stress at the interface. The tetrag-onal contribution to the distortion results in a ratio c a > 1, opposite to that found in the low temperature bulk CoO phase. This distortion leads to a stable Co 2+ spin configuration within the plane of the film