Higher Levels of Cystatin C Are Associated with Worse Cognitive Function in Older Adults with Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort Cognitive Study

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108602/1/jgs12986.pd

Bacterial proteases: targets for diagnostics and therapy

Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined

Quantitative Methods in Economics and Finance

Evaluation of Financial and Actuarial Risk. The research group has focused on several different aspects of quantitative finance. As a first research subject, we faced the problem of pricing credit default swaps (CDSs), which entails the calculation of the risk of default. As a second research subject, we considered the problem of pricing complex derivatives. Precisely, we took into account barrier options on an underlying described by either the geometric fractional Brownian motion or a timechanged Brownian motion. Finally, we dealt with the problem of pricing real options in the presence of stochastic interest rates. Nonlinear Dynamics in Economic and Financial Models. Nonlinear Dynamics is an interdisciplinary area characterized by a rapid and extensive development in recent years, which has proved to be very useful in explaining some important facts in Economics and Finance (such as endogenous fluctuations). In this contribution, we provide an overview of our research on this topic, both in continuous and in discrete time