Hidden geometries in nonlinear theories: a novel aspect of analogue gravity

We show that non-linear dynamics of a scalar field {\phi} may be described as a mod- ification of the spacetime geometry. Thus, the self-interaction is interpreted as a coupling of the scalar field with an effective gravitational metric that is constructed with {\phi} itself. We prove that this process is universal, that is, it is valid for arbi- trary Lagrangian. Our results are compared to usual analogue models of gravitation, where the emergence of a metric appears as a consequence of linear perturbation

Geometric scalar theory of gravity

We present a geometric scalar theory of gravity. Our proposal will be described using the "background field method" introduced by Gupta, Feynman and others as a field theory formulation of general relativity. We analyze previous criticisms against scalar gravity and show how the present proposal avoids these difficulties. This concerns not only the theoretical complaints but also those related to observations. In particular, we show that the widespread belief of the conjecture that the source of scalar gravity must be the trace of the energy-momentum tensor - which is one of the main difficulties to couple gravity with electromagnetic phenomenon in previous models - does not apply to our geometric scalar theory. Some consequences of the new scalar theory are explored.Comment: We did some modifications which do not change the content of the tex

Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection.

HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection and disease progression are not well defined. Using the simian immunodeficiency virus (SIV)-infected rhesus macaque model of AIDS, we found a robust increase in PRRs and inflammatory cytokine gene expression during the acute SIV infection in both peripheral blood and gut mucosa, coinciding with viral replication. PRR expression remained elevated in peripheral blood following the transition to chronic SIV infection. In contrast, massive dampening of PRR expression was detected in the gut mucosa, despite the presence of detectable viral loads. Exceptionally, expression of Toll-like receptor 4 (TLR4) and TLR8 was downmodulated and diverged from expression patterns for most other TLRs in the gut. Decreased mucosal PRR expression was associated with increased abundance of several pathogenic bacterial taxa, including Pasteurellaceae members, Aggregatibacter and Actinobacillus, and Mycoplasmataceae family. Early antiretroviral therapy led to viral suppression but only partial maintenance of gut PRRs and cytokine gene expression. In summary, SIV infection dampens mucosal innate immunity through PRR dysregulation and may promote immune activation, gut microbiota changes, and ineffective viral clearance

Phenotypic heterogeneity of peripheral monocytes in healthy dogs

Monocytes are key cells of the innate immune system. Their phenotypic and functional roles have been investigated in humans, mice and other animals, such as the rat, pig and cow. To date, detailed phenotypic analysis of monocytes has not been undertaken in dogs. Two important surface markers in human monocytes are CD14 and MHC class II (MHC II). By flow cytometry, we demonstrated that canine monocytes can be subdivided into three separate populations: CD14posMHC IIneg, CD14posMHC IIpos and CD14negMHC IIpos. Both light and transmission electron microscopy confirmed the monocytic identity of all three populations. The CD14posMHC IIneg population could be distinguished on an ultrastructural level by their smaller size, the presence of more numerous, larger granules, and more pseudopodia than both of the other populations

Identificação molecular de Heterodera glycines, o nematóide de cistos da soja.

bitstream/CPAC-2010/30252/1/bolpd-211.pd

Trabalho docente na uerj (1995-2008): intensificação, precarização e efeitos de subjetivação

Fundação Oswaldo Cruz (FIOCRUZ, Brasil).Universidade do Estado do Rio de Janeiro (UERJ