The motivation for citizens’ involvement in life sciences research is predicted by age and gender

Open Science is an umbrella term encompassing multiple concepts as open access to publications, open data, open education and citizen science that aim to make science more open and transparent. Citizen science, an important facet of Open Science, actively involves nonscientists in the research process, and can potentially be beneficial for multiple actors, such as scientists, citizens, policymakers and society in general. However, the reasons that motivate different segments of the public to participate in research are still understudied. Therefore, based on data gathered from a survey conducted in Czechia, Germany, Italy, Spain, Sweden, and the UK (N = 5,870), this study explores five types of incentives that can motivate individuals to become involved in life sciences research. The results demonstrate that men and younger individuals are more persuaded by extrinsic motives (external benefits or rewards), as compared with women and older people, who are driven by intrinsic motives (that originates from within an individual). This paper shows that specific strata of the population are differentially motivated to engage in research, thereby providing relevant knowledge for effectively designing public involvement activities that target various groups of the public in research projects

Biomechanical considerations in the pathogenesis of osteoarthritis of the knee

Osteoarthritis is the most common joint disease and a major cause of disability. The knee is the large joint most affected. While chronological age is the single most important risk factor of osteoarthritis, the pathogenesis of knee osteoarthritis in the young patient is predominantly related to an unfavorable biomechanical environment at the joint. This results in mechanical demand that exceeds the ability of a joint to repair and maintain itself, predisposing the articular cartilage to premature degeneration. This review examines the available basic science, preclinical and clinical evidence regarding several such unfavorable biomechanical conditions about the knee: malalignment, loss of meniscal tissue, cartilage defects and joint instability or laxity

Do large femoral heads reduce the risks of impingement in total hip arthroplasty with optimal and non-optimal cup positioning?

The purpose of this study was to assess whether large femoral heads (36–38 mm) improve the range of motion in total hip arthroplasty compared to standard (28–32 mm) femoral heads in the presence of optimal and non-optimal cup positioning. A mathematical model of the hip joint was generated by using a laser scan of a dried cadaveric hip. The range of motion was assessed with a cup inclination and anteversion of reference and with non-optimal cup positions. Large femoral heads increased the range of motion, compared to the 28-mm femoral head, in the presence of a hip prosthesis correctly implanted and even more so in the presence of non-optimal cup positioning. However, with respect to the 32-mm femoral head, large femoral heads showed limited benefits both in the presence of optimal and non-optimal cup positioning