Food Prices and the Multiplier Effect of Export Policy

This paper studies the relationship between export policy and food prices. We show that, when individuals are loss averse, food exporters may use trade policy to shield the domestic economy from large price shocks. This creates a complementarity between the price of food in international markets and export policy. Specifically, unilateral actions by exporting countries give rise to a "multiplier effect": when a shock in the international food market drives up (down) its price, governments respond by imposing export restrictions (subsidies), thus exacerbating the initial shock and soliciting further export activism. We test this theory with a new dataset that comprises monthly information on trade measures across 125 countries and 29 food products for the period 2008-10, finding evidence of a multiplier effect. Global restrictions in a product (i.e. the share of international trade covered by export restrictions) are positively correlated with the probability of imposing a new export restriction on that product, especially for staple foods. Large exporters are found to be more reactive to restrictive measures, suggesting that the multiplier effect is mostly driven by this group. Finally, we estimate that a 1 per cent surge in global restrictions increased international food prices by 1.1 per cent on average during 2008-10. These findings contribute to inform the broader debate on the proper regulation of export policy within the multilateral trading system

Herpes zoster vaccination in the elderly subjects: improving awareness and uptake

Armando Stefanati, Nicoletta Valente, Silvia Lupi, Sara Previato, Matilde Giordani, Giovanni Gabutti Department of Medical Sciences, University of Ferrara, Ferrara, Italy Abstract: Herpes zoster (HZ) is a common disease in adults and older subjects solely related to the reactivation of latent varicella zoster virus in ganglia. The incidence of the disease increases with aging and the decline of varicella zoster virus-specific cell-mediated immunity. HZ has a significant impact on the quality of life of subjects during the acute phase. Besides, pain can persist even for a long time becoming chronic. The chronic pain following HZ is called postherpetic neuralgia, and it is a debilitating long-lasting condition, characterized by metameric pain, allodynia, and hyperalgesia. Therapeutic options against HZ and postherpetic neuralgia are often suboptimal and the impact of the disease and its complications on daily living activities is significant, especially in older subjects. Nowadays, a preventive approach to the disease is possible; as a matter of fact, a high-antigen content live vaccine is available. This vaccine has a good profile in terms of immunogenicity, efficacy, effectiveness, and safety and its use may prevent both HZ and postherpetic neuralgia. Nevertheless, the evaluation of the issues raised in countries that introduced this immunization show that both provider and patient barriers could have prevented a more robust uptake of HZ vaccination. In the USA, HZ immunization storage was expensive, reimbursement was cumbersome, and supply shortages may have limited promotion by the interests of the manufacturer and provider. The doctors did not actively recommend HZ vaccination; on the other hand, subjects were mostly unaware of the HZ vaccine. Several demographic factors, including sex and educational level, could have negatively affected the coverage rates; besides, the clinicians who treat adults focus less on vaccination than those taking care of children. On the other hand, when health care professionals undertook every effort to maximize the uptake of the shingles vaccine (eg, in the UK), the vaccine coverage rate increased very quickly. Keywords: herpes zoster, postherpetic neuralgia, vaccin

PHYSICAL AND VIRTUAL RECONSTRUCTION FOR AN INTEGRATED ARCHAEOLOGICAL MODEL: 3D PRINT AND MAQUETTE

Abstract. Museums perform various tasks such as collecting, cataloguing and preserving the cultural heritage (CH). In addition, they have an institutional task, which is to disseminate the heritage, discovering the most efficient tools to tell how a monument to the origin could have looked. In this process of knowledge and dissemination, digital technologies play an important role. In fact, they allow building a digital archive in which virtual copies of found objects are available to scholars for more or less in-depth analysis. Digital archives of this type also allow the dissemination of scientific data, constituting, if published, databases accessible everywhere. The role of the digital archive is also to preserve the characteristics of the finds, which are often already deteriorated, without worsening the situation through their continuous manipulation or movement. Of course, the construction of digital copies must be done in the most rigorous way so as to guarantee scholars the truthfulness of the data being analysed, and building procedures as standardized as possible to allow their use even by unskilled personnel. Moreover, museums have the very complex task of communicating the heritage, which envisages two steps: reconstruction and communication. The first phase, reconstruction, is a very complex operation, especially in the archaeological field, where there are few documents and the hypotheses are based on principles of similarity. Since no direct reference is available, the reconstruction takes place through comparison with similar objects from the same period, the same area and with the same function. Communication, then, has the task of disseminating the results and the hypotheses made, with the most appropriate tools. 3D printing allows to build three-dimensional models of reality, and therefore immediately comprehensible, even of complex forms, not always achievable with the traditional tools of modelling tools. This article describes this complex process, and its application to the funerary aediculae monument at the Museo Archeologico di Mantova, on the occasion of the refurbishment of the museum and its exhibits. In this experience, the use of new technologies is being investigated in combination with more traditional methods of representation, the maquette, but not less effective.</p

Kinematic bidimensional analysis of the propulsion technique in wheelchair rugby athletes

Wheelchair rugby is a sport ideated for individuals with cervical spinal cord injury (CSCI) which is extremely important for maintaining their neuromuscular abilities and improving their social and psychological wellbeing. However, due to the frequent changes in direction and speed it considerably stresses the players' upper limbs. 13 athletes have undergone two sports-related tests on an inertial drum bench and several kinematic parameters have been registered. Most athletes use a semi-circular pattern which is considered protective for the upper limb. With increasing speed, range of motion (ROM) increases. Release angles increment and contact angles reduce, displacing the push angle forward to increase speed. Instead, the more anterior late push angle used to increase velocity is a factor which further loads the shoulder joint. However, other factors affecting propulsion technique, such as posture and wheelchair set up should be studied to further reduce loading on the upper limb

Large-scale reconfigurable continuously-coupled integrated optical circuits for photonic quantum information processing

Quantum photonic platforms are emerging as the most promising to prove a computational advantage. Here we present a novel reconfigurable integrated interferometer for large-scale implementation of Boson Sampling based on the continuous coupling of waveguides

Experimental Engineering of Arbitrary Qudit States with Discrete-Time Quantum Walks

The capability to generate and manipulate quantum states in high-dimensional Hilbert spaces is a crucial step for the development of quantum technologies, from quantum communication to quantum computation. One-dimensional quantum walk dynamics represents a valid tool in the task of engineering arbitrary quantum states. Here we affirm such potential in a linear-optics platform that realizes discrete-time quantum walks in the orbital angular momentum degree of freedom of photons. Different classes of relevant qudit states in a six-dimensional space are prepared and measured, confirming the feasibility of the protocol. Our results represent a further investigation of quantum walk dynamics in photonics platforms, paving the way for the use of such a quantum state-engineering toolbox for a large range of applications

Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1

The treatment of Human African Trypanosomiasis remains a major unmet health need in sub-Saharan Africa. Approaches involving new molecular targets are important and pteridine reductase 1 (PTR1), an enzyme that reduces dihydrobiopterin in Trypanosoma spp. has been identified as a candidate target and it has been shown previously that substituted pyrrolo[2,3-d]pyrimidines are inhibitors of PTR1 from T. brucei (J. Med. Chem. 2010, 53, 221-229). In this study, 61 new pyrrolo[2,3-d]pyrimidines have been prepared, designed with input from new crystal structures of 23 of these compounds complexed with PTR1, and evaluated in screens for enzyme inhibitory activity against PTR1 and in vitro antitrypanosomal activity. 8 compounds were sufficiently active in both screens to take forward to in vivo evaluation. Thus although evidence for trypanocidal activity in a stage I disease model in mice was obtained, the compounds were too toxic to mice for further development