Global-to-local incompatibility, monogamy of entanglement, and ground-state dimerization: Theory and observability of quantum frustration in systems with competing interactions

Frustration in quantum many body systems is quantified by the degree of incompatibility between the local and global orders associated, respectively, to the ground states of the local interaction terms and the global ground state of the total many-body Hamiltonian. This universal measure is bounded from below by the ground-state bipartite block entanglement. For many-body Hamiltonians that are sums of two-body interaction terms, a further inequality relates quantum frustration to the pairwise entanglement between the constituents of the local interaction terms. This additional bound is a consequence of the limits imposed by monogamy on entanglement shareability. We investigate the behavior of local pair frustration in quantum spin models with competing interactions on different length scales and show that valence bond solids associated to exact ground-state dimerization correspond to a transition from generic frustration, i.e. geometric, common to classical and quantum systems alike, to genuine quantum frustration, i.e. solely due to the non-commutativity of the different local interaction terms. We discuss how such frustration transitions separating genuinely quantum orders from classical-like ones are detected by observable quantities such as the static structure factor and the interferometric visibility.Comment: 11 pages, 7 figures. Matches published versio

Drawing autism : the parental perceptions of the impact art therapy has on communication patterns and the parent-child relationship

This qualitative study examined the parental perceptions of the impact art therapy has on communication patterns and the quality of relationship between a parent and his/her child with autism. The research question that guided this study was, Can art therapy help strengthen the relationship between a parent and his/her child with autism? This investigation utilized both convenience and snowball sampling. This study\u27s findings are based on semi-structured interviews, conducted via phone or video chat, with five parents who have children diagnosed with Autism Spectrum Disorder, and whose children have been treated with art therapy. The findings confirmed that art therapy does in fact strengthen the parent-child relationship. All parents spoke to the fact that art therapy helped them communicate effectively with their child and enabled them to learn more about their child. As the communication developed, parents spoke about the positive effect this had on their relationship. The findings also indicated that art therapy helps children with autism strengthen social skills and think more abstractly to grasp difficult to understand concepts. Implications for practice, policy, and research are discussed

Effective tensor forces and neutron rich nuclei

We study the effects of the tensor term of the effective nucleon-nucleon interaction on nuclear excited states. Our investigation has been conducted by using a self-consistent Random Phase Approximation approach. We investigate various nuclei in different regions of the isotopes chart. Results for a set of calcium isotopes are shown.Comment: 4 pages, 4 figures, 1 table Proc. 10th International Spring Seminar on Nuclear Physics New Quests in Nuclear Structure, Vietri Sul Mare, May 21-25, 201

Characterization of DNA methylation as a function of biological complexity via dinucleotide inter-distances

We perform a statistical study of the distances between successive occurrencies of a given dinucleotide in the DNA sequence for a number of organisms of different complexity. Our analysis highlights peculiar features of the dinucleotide CG distribution in mammalian DNA, pointing towards a connection with the role of such dinucleotide in DNA methylation. While the CG distributions of mammals exhibit exponential tails with comparable parameters, the picture for the other organisms studied (e.g., fish, insects, bacteria and viruses) is more heterogeneous, possibly because in these organisms DNA methylation has different functional roles. Our analysis suggests that the distribution of the distances between dinucleotides CG provides useful insights in characterizing and classifying organisms in terms of methylation functionalities.Comment: 13 pages, 5 figures. To be published in the Philosophical Transactions A theme issue "DNA as information

Macroscopic Observables Detecting Genuine Multipartite Entanglement and Partial Inseparability in Many-Body Systems

We show a general approach for detecting genuine multipartite entanglement (GME) and partial inseparability in many-body-systems by means of macroscopic observables (such as the energy) only. We show that the obtained criteria, the "GME gap" and "the k-entanglement gap", detect large areas of genuine multipartite entanglement and partial entanglement in typical many body states, which are not detected by other criteria. As genuine multipartite entanglement is a necessary property for several quantum information theoretic applications such as e.g. secret sharing or certain kinds of quantum computation, our methods can be used to select or design appropriate condensed matter systems.Comment: 4 pages, 3 figures, published version, title extende

CO2 Capture from Industrial Sources by High-temperature Sorbents

Among the emerging CO2 capture technologies, systems based on high temperature (HT) regenerable sorbents had a significant development in recent years. In addition to power plants, HT sorbents technologies can be particularly promising for CO2 capture in carbon intensive industrial processes such as cement plants, steel mills and hydrogen plants. Calcium looping (CaL) is a combined post-combustion and oxyfuel combustion technology which uses calcium oxide (CaO) as CO2 sorbent. In this process, CO2 in combustion flue gases is absorbed in a carbonator reactor by forming calcium carbonate (CaCO3) through the exothermic carbonation reaction. Carbonated sorbent is then regenerated to CaO through the reverse calcination reaction in a calciner, where reaction heat is provided by oxyfuel combustion. A CO2 concentrated stream is therefore released from the calciner, which can be purified and compressed as in conventional oxyfuel product gas. Calcium looping is particularly promising for application in cement plants, because the raw materials used for the production of clinker (the energy intensive process in cement manufacturing) are rich of CaCO3, which is also the starting material of the CaL CaO sorbent. Therefore, no additional material needs to be imported or is released as waste when CaL is integrated in a cement plant. Two main configurations can be assumed to integrate the CaL process into a cement burning line: (i) the tail-end configuration, where the CaL process is used as a post-combustion, end-of-pipe capture process and (ii) a highly integrated configuration, where the CaL reactors are integrated into the raw meal preheating tower of the clinker production process and the CaL oxyfuel calciner coincides with the raw meal pre-calciner. Another class of processes where CaO is used as CO2 sorbent is sorption enhanced reforming (SER) technologies, where CO2 is absorbed within a steam methane reforming (SMR) reactor. The advantage of this class of processes is that the heat released by sorbent carbonation reaction matches very well with the steam methane reforming reaction. Moreover, the removal of the CO2 reaction product allows a greater advancement of the reforming and water gas shift (WGS) reactions. As a result, with a SER reactor, a H2 production and CO2 separation are performed in a single adiabatic reactor operating at moderate temperature (~650°C) instead of a sequence of reactors for steam reforming (~900°C), WGS (200-400°C) and CO2 separation (~30°C) operating in a wide temperature range as in conventional H2 production processes. In addition to material development, the main challenge in SER technologies is in the endothermic sorbent regeneration step. Several process schemes have been proposed for sorbent calcination, such as: (i) oxyfuel combustion, (ii) high temperature heat exchangers, (iii) direct contact heating with hot solids from a chemical looping combustion loop. Both fluidized bed and packed bed reactors are proposed for SER processes operating at different temperature and pressure range. If a CO2 sorbent is active at intermediate temperatures (~400°C), such as in the case of hydrotalcite-based sorbents, it can be adopted in sorption enhanced WGS (SEWGS) processes. As in the SER principle, the in-situ removal of CO2 form the gas phase allows a higher advancement of the WGS reaction. Therefore, H2-rich gas production and CO2 separation can be performed in a single pressurized reactor. While this concept can be adopted in hydrogen production plants, a promising application is in steel mills, where most of the CO2 emissions are associated to the combustion of the blast furnace gas (BFG) in the steel mill power plant. BFG is a byproduct of the pig iron production process and is a low calorific value fuel rich of CO, CO2 and N2. By processing BFG in a SEWGS reactor, a H2-N2 stream is produced, which can be burned at high efficiency in a low emission combined cycle. CaL, SER and SEWGS processes illustrated above for CO2 capture in industry, are being developed in the three ongoing EU FP7 and H2020 projects Cemcap (G.A. 641185), Ascent (G.A 608512) and Stepwise (G.A. 640769). In this work, the potential of these processes in terms of CO2 capture efficiency and energy efficiency will be discussed and compared with benchmark technologies, based on process integration and simulation studies

Small molecules targeting endocytic uptake and recycling pathways

Over the past years a growing number of studies highlighted the pivotal role of intracellular trafficking in cell physiology. Among the distinct transport itineraries connecting the endocytic system, both internalization (endocytosis) and recycling (endocytic recycling) pathways were found fundamental to ensure cellular sensing, cell-to-cell communication, cellular division, and collective cell migration in tissue specific-contexts. Consistently, the dysregulation of endocytic trafficking pathways is correlated with several human diseases including both cancers and neurodegeneration. Aimed at suppress specific intracellular trafficking routes involved in disease onset and progression, huge efforts have been made to identify small molecule inhibitors with suitable pharmacological properties for in vivo administration. Here, we review most used drugs and recently discovered small molecules able to block endocytosis and endocytic recycling pathways. We characterize such pharmacological inhibitors by emphasizing their target specificity, molecular affinity, biological activity and efficacy in both in vitro and in vivo experimental models