8 research outputs found
B Cell Precursor Populations in Fetal and Neonatal Rat Liver: Frequency, Topography and Antigenic Phenotype
No full textOntogeny of T lymphocyte differentiation in the human fetus: Acquisition of phenotype and functions
No full textTen years after acquiring an HIV-1 infection: a study in a cohort of eleven neonates infected by aliquots from a single plasma donation
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The Omenn's syndrome: Histological, immunohistochemical and ultrastructural evidence for a partial T cell deficiency evolving in an abnormal proliferation of T lymphocytes and S-100+/T-6+ Langerhans-like cells
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Reconstitution of the immune system after hematopoietic stem cell transplantation in humans
No full textHematopoietic stem cell transplantation is associated with a severe immune deficiency. As a result, the patient is at high risk of infections. Innate immunity, including epithelial barriers, monocytes, granulocytes, and NK cells recovers within weeks after transplantation. By contrast, adaptive immunity recovers much slower. B- and T-cell counts normalize during the first months after transplantation, but in particular, T-cell immunity may remain impaired for years. During the last decade, much of the underlying mechanisms have been identified. These insights may provide new therapies to accelerate recovery
