Electrokinetic delivery of reagents for groundwater remediation

L'abstract è presente nell'allegato / the abstract is in the attachmen

Impaired coronary blood flow at higher heart rates during atrial fibrillation: investigation via multiscale modelling

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the present work is to computationally explore whether and to what extent ventricular rate during AF affects the coronary perfusion. Methods. AF is simulated at different ventricular rates (50, 70, 90, 110, 130 bpm) through a 0D-1D multiscale validated model, which combines the left heart-arterial tree together with the coronary circulation. Artificially-built RR stochastic extraction mimics the \emph{in vivo} beating features. All the hemodynamic parameters computed are based on the left anterior descending (LAD) artery and account for the waveform, amplitude and perfusion of the coronary blood flow. Results. Alterations of the coronary hemodynamics are found to be associated either to the heart rate increase, which strongly modifies waveform and amplitude of the LAD flow rate, and to the beat-to-beat variability. The latter is overall amplified in the coronary circulation as HR grows, even though the input RR variability is kept constant at all HRs. Conclusions. Higher ventricular rate during AF exerts an overall coronary blood flow impairment and imbalance of the myocardial oxygen supply-demand ratio. The combined increase of heart rate and higher AF-induced hemodynamic variability lead to a coronary perfusion impairment exceeding 90-110 bpm in AF. Moreover, it is found that coronary perfusion pressure (CPP) is no longer a good measure of the myocardial perfusion for HR higher than 90 bpm.Comment: 8 pages, 5 figures, 3 table

An Experience in Mentoring: Shaping Young Mathematical Minds

The Math PLUS program is a partnership between Linfield College and a local middle school which seeks to encourage more mathematics in local and regional science fairs. Linfield students are paired with middle school students to mentor science fair projects that are required to have a mathematical focus. We briefly discuss an overview of the program—its goals, structure and execution—before touching on our personal experiences as mentors for Yamhill-Carlton Intermediate School students. We also provide suggestions for improvements for those looking to implement similar programs at their own institution. The program is funded by a Dolciani Mathematics Enrichment Grant

How to classify the stylohyoid complex syndrome in the ICHD

We have read the International Classification of Headache Disorders, third edition (beta) (ICHD-3 beta), and for the first time headaches are attributed to inflammation of the stylohyoid ligament (SL). It is included among the secondary headaches in “Headache or facial pain attributed to disorder of the cranium, neck, eyes, ears, nose, sinuses, teeth, mouth or other facial or cervical structure.

Renovación de centros industriales. Integración urbana y vivienda multifamiliar en San Andresito de la 38

Artículo de gradoEl proyecto trabajado durante décimo semestre en el grupo 3 se desarrolló en San Andresito de la 38 -ubicado en el centro de Bogotá- en el barrio Los Ejidos, donde a través de la renovación urbana se busca transformar la infraestructura del barrio bajo parámetros de diseño paisajístico; donde el espacio público verde, las plazas, parques y equipamientos de vivienda pretenden mejorar la calidad de vida de los habitantes y transeúntes del sector. Donde se identificaron problemáticas como: la apropiación del espacio público y la trasformación del cambio de uso ocasionado en el año 1960 que generaron vacíos urbanos. Esta situación, a su vez generó deficiencia en áreas verdes púbicas, abandono de fábricas que ocasionan espacios residuales que no aportan un enriquecimiento visual y al paisajismo urbanístico del sector de igual forma se encontró un porcentaje mínimo de vivienda en relación a los demás usos. Como estrategia se propone renovar el sector desde el ámbito del sistema ambiental, hasta la reorganización del comercio e implementación de nuevos usos del suelo como equipamientos, educativos y vivienda.INTRODUCCIÓN 1. METODOLOGÍA 2. RESULTADOS 3. DISCUSIÓN 4. CONCLUSIONES REFERENCIAS ANEXOSPregradoArquitect

Supernova neutrino physics with a nuclear emulsion detector

The existence of the coherent neutrino-nucleus scattering reaction requires to evaluate, for any detector devoted to WIMP searches, the irreducible background due to conventional neutrino sources and at same time, it gives a unique chance to reveal supernova neutrinos. We report here a detailed study concerning a new directional detector, based on the nuclear emulsion technology. A Likelihood Ratio test shows that, in the first years of operations and with a detector mass of several tens of tons, the observation of the supernova signal can be achieved. The determination of the distance of the supernova from the neutrinos and the observation of $^8$B neutrinos are also discussed.Comment: 22 pages, 12 figure

Sperm glyceraldehyde 3-phosphate dehydrogenase gene expression in asthenozoospermic spermatozoa

It has been suggested that the energy required for sperm motility is produced by oxidative phosphorylation while glycolysis seems to be an important source for ATP transmission along the flagellum. Some studies have investigated the chemical and kinetic properties of the enzyme glyceraldehyde 3‐phosphate dehydrogenase to identify any changes in the regulation of glycolysis and sperm motility. In contrast, there are few studies analyzing the genetic basis of hypokinesis. For this reason, we investigated the glyceraldehyde 3‐phosphate dehydrogenase gene in human sperm to evaluate whether asthenozoospermia was correlated with any changes in its expression. Semen examination and glyceraldehyde 3‐phosphate dehydrogenase gene expression studies were carried out on 116 semen samples divided into two groups – Group A consisted of 58 normokinetic samples and Group B of 58 hypokinetic samples. Total RNA was extracted from spermatozoa, and real‐time PCR quantification of mRNA was carried out using specific primers and probes. The expression profiles for the Groups A and B were very similar. The mean delta Ct was as follows – Group A, 5.79 ± 1.04; Group B, 5.47 ± 1.27. Our study shows that in human sperm, there is no difference in glyceraldehyde 3‐phosphate dehydrogenase gene expression between samples with impaired motility and samples with normal kinetics. We believe that this study could help in the understanding of the molecular mechanisms of sperm kinetics, suggesting that hypomotility may be due to a possible posttranscriptional impairment of the control mechanism, such as mRNA splicing, or to posttranslational changes