Information Systems and Assemblages

International audienceThe theme for the 2014 IFIP WG 8.2 working conference was ‘Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations’. The motivation behind the choice of the conference theme has been the increasing appreciation of notions of emergence, heterogeneity and temporality in IS studies. We found that the conference provided an opportune occasion for inviting scholars interested in exploring these notions, their relevance and promise for IS studies. The concept of the ‘assemblage’ [1], already referenced in IS studies, as will be discussed below, and with significant popularity in other fields, such as anthropology, geography and cultural studies, provided the stepping stone for approaching the heterogeneous, emergent and situated nature of information systems and organization. In particular, we opted for highlighting the ‘global assemblage’[2] as a metaphor to talk about challenging yet often creative tensions that emerge as global imperatives (geographical, intellectual, procedural and others) interact with local arrangements of actors, artefacts and organizations. Here ‘global’ does not mean universal or everywhere, but mobile, abstractable, and capable of recontextualization across diverse social and cultural situations.This book provides a collection of contributions by scholars who responded to our invitation, adding depth and breadth to our understanding of the concept and its value for IS studies. At the same time, some contributors chose to discuss emergence, heterogeneity and situatedness in different terms, drawing upon alternative theoretical traditions and concepts. The result has been an engaging and stimulating mix of ideas that points towards the ‘multiple’ trajectories - current and future - of this exciting stream of research

Isosbestic points in the spectral function of correlated electrons

We investigate the properties of the spectral function A(omega,U) of correlated electrons within the Hubbard model and dynamical mean-field theory. Curves of A(omega,U) vs. omega for different values of the interaction U are found to intersect near the band-edges of the non-interacting system. For a wide range of U the crossing points are located within a sharply confined region. The precise location of these 'isosbestic points' depends on details of the non-interacting band structure. Isosbestic points of dynamic quantities therefore provide valuable insights into microscopic energy scales of correlated systems.Comment: 16 pages, 5 figure

Notes on S-Matrix of Non-critical N=2 String

In this paper we discuss the scattering S-matrix of non-critical N=2 string at tree level. First we consider the \hat{c}<1 string defined by combining the N=2 time-like linear dilaton SCFT with the N=2 Liouville theory. We compute three particle scattering amplitudes explicitly and find that they are actually vanishing. We also find an evidence that this is true for higher amplitudes. Next we analyze another \hat{c}<1 string obtained from the N=2 time-like Liouville theory, which is closely related to the N=2 minimal string. In this case, we find a non-trivial expression for the three point functions. When we consider only chiral primaries, the amplitudes are very similar to those in the (1,n) non-critical bosonic string.Comment: 27 pages, harvmac, section 5 modified: a relation to (1,n) non-critical bosonic string adde

Digital Drugs: an anatomy of new medicines

Medicines are digitalized as aspects of their regulation and use are embodied in or draw from interlinked computerized systems and databases. This paper considers how this development changes the delivery of health care, the pharma industry, and regulatory and professional structures, as it reconfigures the material character of drugs themselves. It draws on the concept of assemblage in presenting a theory-based analysis that explores digital drugs’ ontological status including how they embody benefit and value. The paper addresses three interconnected domains – that of use of drugs (practice), of research (epistemology) and of regulation (structures)

Understanding the Emergent Structure of Competency Centers in Post-implementation Enterprise Systems

Part 3: Structures and NetworksInternational audiencePrior research provides conflicting insights about the link between investment in enterprise systems and firm value and in the ES governance mechanisms. The literature generally suggests that management should cultivate its technical and organizational expertise to derive value from currently deployed Enterprise Systems (ES) [8]. In the realm of practice, ERP vendors and configuration/integration partners strongly recommend the creation of an organizational structure to govern the ERP implementation and post-implementation process to improve project success and extract greater value from the ES investment. The ES literature, while unclear on the formation, and functioning of ES governance units, suggests the need for formal and fixed governance structures. This research utilizes Deleuze’s assemblage theory and emergence theory to explain the genesis and evolution of the governing ‘structure’ known as the Competency Center (CC). Our results illustrate the business needs driving the structuring processes behind the CC, are also those that lead to unintended and destabilizing outcomes. Whether the CC ‘assemblage’ survives to provide value depends on how the emergent issues are handled and how the assemblages are “positioned”. This research suggests effective ES governance is not derived from a prescribed step-wise process yielding formal structures, but rather form an organic process of assemblage

Gene-gene Interaction Analyses for Atrial Fibrillation

Atrial fibrillation (AF) is a heritable disease that affects more than thirty million individuals worldwide. Extensive efforts have been devoted to the study of genetic determinants of AF. The objective of our study is to examine the effect of gene-gene interaction on AF susceptibility. We performed a large-scale association analysis of gene-gene interactions with AF in 8,173 AF cases, and 65,237 AF-free referents collected from 15 studies for discovery. We examined putative interactions between genome-wide SNPs and 17 known AF-related SNPs. The top interactions were then tested for association in a