A possible far-ultraviolet flux-dependent core mass function in NGC 6357

To derive the properties of the dense cores in the galactic star-forming complex NGC6357 and to investigate the effects of an intense far-UV radiation field on their properties, we mapped the region at 450 and 850 micron, and in the CO(3-2) line with the JCMT. We also made use of the Herschel Hi-GAL data at 70 and 160 micron. We used Gaussclumps to retrieve 686 compact cores embedded in the diffuse sub-mm emission and constructed their SED from 70 to 850 micron, from which we derived mass and temperature. The estimated mass completeness limit is ~5Mo. We divided the observed area in an 'active' region, exposed to the far-UV radiation from the more massive members of three star clusters (411 cores), and a 'quiescent' region, less affected by far-UV radiation (275 cores). We also attempted to select a sample of pre-stellar cores based on cross-correlation with 70 micron emission and red WISE point sources. Most of the cores above the mass completeness limit are likely to be gravitationally bound. The fraction of gas in dense cores is very low, 1.4%. We found a mass-size relation log(M/Mo) ~ (2.0-2.4) x log (D/arcsec), depending on the precise selection of the sample. The temperature distributions in the two sub-regions are clearly different, peaking at ~25K in the quiescent region and at ~35K in the active region. The core mass functions are different as well, at a 2sigma level, consistent with a Salpeter IMF in the quiescent region and flatter than that in the active region. The dense cores lying close to the HII regions are consistent with pre-existing cores being gradually engulfed by a PDR and photoevaporating. We attribute the different global properties of dense cores in the two sub-regions to the influence of the far-UV radiation field.Comment: 16 pages, 18 figures, 3 tables (1 only at CDS); accepted by Astronomy & Astrophysic

Balancing, Proportionality, and Constitutional Rights

In the theory and practice of constitutional adjudication, proportionality review plays a crucial role. At a theoretical level, it lies at core of the debate on rights adjudication; in judicial practice, it is a widespread decision-making model characterizing the action of constitutional, supra-national and international courts. Despite its circulation and centrality in contemporary legal discourse, proportionality in rights-adjudication is still extremely controversial. It raises normative questions—concerning its justification and limits—and descriptive questions—regarding its nature and distinctive features. The chapter addresses both orders of questions. Part I centres on the justification of proportionality review, the connection between proportionality, balancing and theories of rights and the critical aspects of this connection. Part II identifies and analyses the different forms of proportionality both in review, as a template for rights-adjudication, and of review, as a way of defining the scope and limits of adjudication

Understanding refugee durable solutions by international players: Does dialogue form a missing link?

This study evaluates durable solutions in relation to refugees from East Africa. It particularly focuses on the Great Lakes countries of Rwanda, Burundi, Democratic Republic of Congo and Uganda. The study is based on the conviction that these four countries have never had peaceful transfer of power which in essence has been a major contributing factor to political violence that has caused forced mass migration in the region to this day. The use of force or military suppression has been a norm since independence of these countries in the early 1960s. This suppression has continuously forced many people to flee their homes facing abuse of their human rights, dictatorship, persecution, indiscriminate arrests, ethnic wars and political violence. Based on a survey used to collect data and in-depth interviews with selected refugees from the Great Lakes region living in Cape Town, South Africa, this paper seeks to understand durable solutions through analysing the current refugee situation. It demonstrates that durable solutions can present both challenges and solutions. It also revisits the concept of durable solutions and seeks to re-evaluate whether these various solutions offer a chance for dialogue. With the aid of a legal perspective on the refugee situation in the region, the paper qualifies the concepts of dialogue as a mechanism for peace building as well as driver for voluntary repatriation.IBS

Voices in exile African refugees and freedom of expression

Funded by the Commission of the European UnionAvailable from British Library Document Supply Centre-DSC:m01/27102 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo

Histone deacetylase (HDAC) inhibitors offer a promising strategy for cancer therapy, and the first generation HDAC inhibitors are currently in the clinic. Entirely novel ketone HDAC inhibitors have been developed from the cyclic tetrapeptide apicidin. These compounds show class I subtype selectivity and levels of cellular activity comparable to clinical candidates. A representative example has demonstrated tumor growth inhibition in a human colon HCT-116 carcinoma xenograft model comparable to known inhibitors