79 research outputs found

    Development of the university image positioning methods in the context of its marketing strategy

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    Purpose: The note aims to study the steps actions algorithm in the positioning of university image, based on the method of using official media sites and searching systems and social networks. Design/Methodology/Approach: Today in the digital economy, higher educational establishments should take advantage of the opportunities arising from the involvement of the digital infrastructure in the process of their functioning. The positioning of an existing service or product usually takes the form of repositioning. The basis of the methodic apparatus of this study is the method of using official media sites and searching systems and social networks, which is used in the preparation of the steps algorithm in the university’s image positioning. Findings: The steps algorithm in the university image positioning is based on the method of using official media sites and searching systems and social networks. This method is developed by the authors and substantiated for the implementation in the sphere of higher educational establishments. Practical implications: In practice, we are talking about the formation of a mechanism function to provide the basic steps necessary to build an algorithm of the higher educational establishment image positioning. Originality/value: The concept "positioning" is the most often associated with persons (politicians, "stars") and companies engaged in the production or promotion of goods or services and positioning themselves to create their image, but not about the university positioning.peer-reviewe

    Suppression of 2D superconductivity by the magnetic field: quantum corrections vs superconductor-insulator transition

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    Magnetotransport of superconducting Nd_{2-x}Ce_xCuO_{4+y} (NdCeCuO) films is studied in the temperature interval 0.3-30 K. The microscopic theory of the quantum corrections to conductivity, both in the Cooper and in the diffusion channels, qualitatively describes the main features of the experiment including the negative magnetoresistance in the high field limit. Comparison with the model of the field-induced superconductor-insulator transition (SIT) is included and a crossover between these two theoretical approaches is discussed.Comment: 5 pages, 4 figures. Submitted to JETP Letter

    Effect of vasopressin on the expression of genes for key enzymes of interstitial hyaluronan turnover and concentration ability in WAG rat kidneys

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    In mammals, arginine-vasopressin (AVP) is a major hormone involved in the regulation of renal water reabsorption, acting via an increase in the osmotic permeability of the collecting duct epithelium. The AVP-induced intracellular events include, as an essential step, the trafficking of the vesicles containing the water channels, aquaporin-2, to the apical plasma membrane of the collecting duct principal cells. The interstitium of the renal inner medulla contains abundant linear negatively charged glycosaminoglycan hyaluronan (HA), which affects the water flow depending on their polymeric state. Using real-time RT-PCR, we tested the assumption that the renal hyaluronan may be involved in the longterm vasopressin effect on water reabsorption. The expression of the genes encoding hyaluronan synthase-2 (Has2) and hyaluronidase-1, 2 (Hyal1, Hyal2) in the kidneys of Wistar Albino Glaxo (WAG) was studied. Has2 mRNA content was the highest in the kidney papilla of the hydrated rats. The V2 receptor-selective vasopressin analog dDAVP (100 μg/kg bw, ip, twice a day for 2 days) induced a considerable decrease in Has2 mRNA content in the papilla with less pronounced changes in the cortex. In contrast to Has2, dDAVP treatment caused a significant increase in Hyal1 and Hyal2 mRNA content in the renal papilla. There was a good fit between Hyal1 and Hyal2 transcriptional level and changes in hyaluronidase activity in the renal tissue. It was suggested that vasopressin is able to inhibit the synthesis of hyaluronan and concomitantly promotes its degradation in the renal papilla interstitium, thereby facilitating water flow between elements of the renal countercurrent system. The implications for this effect are discussed in the context of the literature data

    Anomalous Behavior near T_c and Synchronization of Andreev Reflection in Two-Dimensional Arrays of SNS Junctions

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    We have investigated low-temperature transport properties of two-dimensional arrays of superconductor--normal-metal--superconductor (SNS) junctions. It has been found that in two-dimensional arrays of SNS junctions (i) a change in the energy spectrum within an interval of the order of the Thouless energy is observed even when the thermal broadening far exceeds the Thouless energy for a single SNS junction; (ii) the manifestation of the subharmonic energy gap structure (SGS) with high harmonic numbers is possible even if the energy relaxation length is smaller than that required for the realization of a multiple Andreev reflection in a single SNS junction. These results point to the synchronization of a great number of SNS junctions. A mechanism of the SGS origin in two-dimensional arrays of SNS junctions, involving the processes of conventional and crossed Andreev reflection, is proposed.Comment: 5 pages, 5 figure

    Subgap anomaly and above-energy-gap structure in chains of diffusive SNS junctions

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    We present the results of low-temperature transport measurements on chains of superconductor--normal-constriction--superconductor (SNS) junctions fabricated on the basis of superconducting PtSi film. A comparative study of the properties of the chains, consisting of 3 and 20 SNS junctions in series, and single SNS junctions reveals essential distinctions in the behavior of the current-voltage characteristics of the systems: (i) the gradual decrease of the effective suppression voltage for the excess conductivity observed at zero bias as the quantity of the SNS junctions increases, (ii) a rich fine structure on the dependences dV/dI-V at dc bias voltages higher than the superconducting gap and corresponding to some multiples of 2\Delta/e. A model to explain this above-energy-gap structure based on energy relaxation of electron via Cooper-pair-breaking in superconducting island connecting normal metal electrods is proposed.Comment: RevTex, 5 pages, 4 figure

    THE ROLE OF CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME AFTER THE EMERGENCE OF MORE POWERFUL INHIBITORS OF P2Y12 RECEPTOR

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    The role of P2Y12 receptor blocker clopidogrel after the introduction into clinical practice of new, more powerful and stable operating drugs belonging to this class of antiplatelet agents is discussed. The advantages and disadvantages of each of the currently used antiplatelet drugs that block the receptor P2Y12 are reviewed. On the basis of the analysis concludes that, despite the emergence of new antiplatelet agents clopidogrel, appears to be widely used for a long time in the treatment of patients with acute coronary syndrome and / or after coronary stenting. This is primarily due to the presence of large evidence base, and confirmation of safety of long-term therapy clopidogrel.</p

    STUDY OF THE EFFECT OF HYPOTHERMIC CONSERVATION ON THE INTRACELLULAR SODIUM CONCENTRATION IN THE ENDOTHELIUM OF CORNEAL TRANSPLANTS

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    Endothelial keratoplasty has become the treatment of choice for corneal endothelial dysfunction. Advancements in the surgical treatment of corneal endothelial diseases depend on progress in graft conservation and its related advantages in assessing the suitability of grafts for transplantation. Transport of water and ions by cornea endothelium is important for the optic properties of cornea. In this work, we study the intracellular sodium concentration in cornea endothelial cells in samples of pig cornea that underwent hypothermic conservation for 1 and 10 days and endothelial cells of human cornea grafts after 10-day conservation. The concentration of intracellular sodium in preparations of endothelial cells was assayed using fluorescent dye SodiumGreen. The fluorescent images were analyzed with the custom-made computer program CytoDynamics. An increased level of intracellular sodium was shown in the endothelium after 10-day conservation in comparison with one-day conservation (pig samples). Sodium permeability of pig endothelial cell plasma membranes significantly decreased in these samples. Assessment of intracellular sodium in human cornea endothelium showed a higher level – as was in analogues pig samples of the corneal endothelium. The assay of the intracellular sodium balance concentration established in endothelial cells after hypothermic conservation in mediums L-15 and Optisol-GS showed a significant advantage of specialized me dium Optisol-GS. The balanced intracellular concentration after 10 days of hypothermic conservation was significantly lower in cells incubated at 4 °C in Optisol-GS (L-15, 128 ± 14,  n = 15; Optisol-GS, 108 ± 14, n = 11; mM, p &lt; 0.001). Intracellular sodium concentration could be a useful parameter for assessing cornea endothelium cell viability

    Superconductivity on the localization threshold and magnetic-field-tuned superconductor-insulator transition in TiN films

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    Temperature- and magnetic-field dependent measurements of the resistance of ultrathin superconducting TiN films are presented. The analysis of the temperature dependence of the zero field resistance indicates an underlying insulating behavior, when the contribution of Aslamasov-Larkin fluctuations is taken into account. This demonstrates the possibility of coexistence of the superconducting and insulating phases and of a direct transition from the one to the other. The scaling behavior of magnetic field data is in accordance with a superconductor-insulator transition (SIT) driven by quantum phase fluctuations in two-dimensional superconductor. The temperature dependence of the isomagnetic resistance data on the high-field side of the SIT has been analyzed and the presence of an insulating phase was confirmed. A transition from the insulating to a metallic phase is found at high magnetic fields, where the zero-temperature asymptotic value of the resistance being equal to h/e^2.Comment: 5 pages, 4 eps figures, RevTeX4, Published versio

    Localization and Superconductivity in Doped Semiconductors

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    Motivated by the discovery of superconductivity in boron-doped (B-doped) diamond, we investigate the localization and superconductivity in heavily doped semiconductors. The competition between Anderson localization and s-wave superconductivity is investigated from the microscopic point of view. The effect of microscopic inhomogeneity and the thermal fluctuation in superconductivity are taken into account using the self-consistent 1-loop-order theory with respect to superconducting fluctuation. The crossover from superconductivity in the host band to that in the impurity band is described on the basis of the disordered three-dimensional attractive Hubbard model for binary alloys. We show that superconductor-insulator transition (SIT) accompanies the crossover. We point out an enhancement of Cooper pairing in the crossover regime. Further localization of the electron wave function gives rise to incoherent Cooper pairs and the pseudogap above T_c. A global phase diagram is drawn for host band superconductivity, impurity band superconductivity, Anderson localization, Fermi liquid state, and pseudogap state. A theoretical interpretation is proposed for superconductivity in the doped diamond, SiC, and Si.Comment: Final version for publication. To appear in J. Phys. Soc. Jpn. (2009) No.
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