1,217 research outputs found
Comment on "Observation of a Push Force on the End Face of a Nanometer Silica Filament Exerted by Outgoing Light" [PRL 101, 243601 (2008)]
A brief discussion is given on the recent experiment of She et al. [Phys.
Rev. Lett. 101, 243601 (2008), arXiv:0806.2442], in relation to the
Abraham-Minkowski energy-momentum problem.Comment: 1 page latex. The text is partially reformulated. To appear as a
Comment in Phys. Rev. Let
Possible relationships between solar activity and atmospheric constituents
The large body of data on solar variations and atmospheric constituents collected between 1902 and 1953 by the Astrophysical Observatory of the Smithsonian Institution (APO) was examined. Short-term variations in amounts of atmospheric aerosols and water vapor due to seasonal changes, volcanic activity, air pollution, and frontal activity are discussed. Preliminary evidence indicates that increased solar activity is at times associated with a decrease in attenuation due to airborne particulates
Dust Storms in Space?
Primarily from the Pioneer 8 and 9 results, it is concluded that the flux of picogram sized dust particles near the earth's orbit has been constant to within the observational limits over three years of observation. In particular, since dust streams are not observed, they cannot explain microphone detected events. However, the possibility of rare events due to dust blown directly off a cometary nucleus (such as that reported for Comet Bennett) cannot be completely ruled out
Theory of Optical Tweezers
We derive a partial-wave (Mie) expansion of the axial force exerted on a
transparent sphere by a laser beam focused through a high numerical aperture
objective. The results hold throughout the range of interest for practical
applications. The ray optics limit is shown to follow from the Mie expansion by
size averaging. Numerical plots show large deviations from ray optics near the
focal region and oscillatory behavior (explained in terms of a simple
interferometer picture) of the force as a function of the size parameter.
Available experimental data favor the present model over previous ones.Comment: 4 pages, 3 figure
Application of Lippmann interference photography to data storage
Lippmann's interference photography is an elegant process to record coloured images in the volume of a sensitive material. We propose to use this technique for wavelength multiplexed data storage in a page-oriented approach. Using computer simulations, we demonstrate that the capacities reached with this technique are similar to those reached by volume holographic data storage
Complications of Intrathecal Baclofen Pump: Prevention and Cure
Increasingly, spasticity is managed with surgically implanted Intrathecal Baclofen pumps. Intrathecal Baclofen pump revision surgery unrelated to programmable pump end-of-life is not uncommon, requiring special attention during pre-, intra-, and postoperative management. We aimed to identify and describe complications of Intrathecal Baclofen pump as well as to report avoidance and management of complications. Methods and Materials. Through 2002–2006, at the department of neurosurgery, Henry Ford and Oakwood Health Systems, Intrathecal Baclofen pumps were implanted in 44 patients: 24 children versus 20 adults; 30 “primary-implant-patients”; 14 “revision-only patients”. We evaluated reasons for revision surgeries and diagnostic workup requirements. Results. Eight primary-implant-patients required 14 revisions and 7 of revision-only patients needed 13 procedures. Seven patients with slowly increasing baclofen-resistant spasticity had either (i) unsuspected pump-catheter connector defects, (ii) an X-ray-documented pump-catheter connector defect, (iii) X-ray-demonstrated fractured catheter with intrathecal fragment. Implant infections occurred in 4 cases. Scintigraphy revealed occult CSF leakage N=1 and intrinsic pump failure N=1. Conclusion. Intrathecal Baclofen pumps, although very gratifying, have a high, technique-related complication incidence during implant life. Meticulous technique, high clinical suspicion, appropriate workup, and timely surgical management can reduce surgical complications of Intrathecal Baclofen pump implantation
On the Relation between Solar Activity and Clear-Sky Terrestrial Irradiance
The Mauna Loa Observatory record of direct-beam solar irradiance measurements
for the years 1958-2010 is analysed to investigate the variation of clear-sky
terrestrial insolation with solar activity over more than four solar cycles.
The raw irradiance data exhibit a marked seasonal cycle, extended periods of
lower irradiance due to emissions of volcanic aerosols, and a long-term
decrease in atmospheric transmission independent of solar activity. After
correcting for these effects, it is found that clear-sky terrestrial irradiance
typically varies by about 0.2 +/- 0.1% over the course of the solar cycle, a
change of the same order of magnitude as the variations of the total solar
irradiance above the atmosphere. An investigation of changes in the clear-sky
atmospheric transmission fails to find a significant trend with sunspot number.
Hence there is no evidence for a yet unknown effect amplifying variations of
clear-sky irradiance with solar activity.Comment: 16 pages, 7 figures, in press at Solar Physics; minor changes to the
text to match final published versio
Self-assembly in patchy proteins: From transient networks to attractive glasses
Dynamic properties of crowded protein solutions are difficult to predict and control. This for example considerably limits our ability to create stable and injectable formulations of proteins or peptides at high concentrations. Another physiologically relevant case is presbyopia, or age-related farsightedness, where the pathological stiffening of the eye lens can be related to a liquid-solid transition of the protein mixtures inside the eye lens cells1. It is thus essential to achieve a quantitative understanding of the link between the molecular structure of the proteins and the interactions between them, and how these interactions influence the stability, dynamics and flow properties of the solutions as a function of their concentration. Here we show how we can use a combination of advanced characterization techniques1-4 such as neutron spin echo, small-angle scattering, 3D cross correlation light scattering and microrheology, combined with state-of-the-art computer simulations to assess and predict interparticle interactions and their impact on the dynamics and flow behavior of crowded protein solutions. We particularly point out the enormous influence of weak attractive interactions known to exist between many globular proteins, and demonstrate the dramatic effect of an interaction potential anisotropy such as attractive patches4 and shape anisotropy on the dynamic properties.
[1] G. Foffi, G. Savin, S. Bucciarelli, N. Dorsaz, G. Thurston, A. Stradner, P. Schurtenberger; A Hard Sphere-Like Glass Transition in Eye Lens Alpha Crystallin Solutions ; Proc. Natl. Acad. Sci. U. S. A., 111, 16748-16753 (2014).
[2] F. Cardinaux, E. Zaccarelli, A. Stradner, S. Bucciarelli, B. Farago, S. Egelhaaf, F. Sciortino, P. Schurtenberger; Cluster-driven dynamical arrest in concentrated lysozyme solutions J. Phys. Chem. B, 115, 7227 (2011).
[3] S. Bucciarelli, L. Casal-Dujat, C. De Michele, F. Sciortino, J. Dhont, J. Bergenholtz, B. Farago, P. Schurtenberger, and A. Stradner; Unusual Dynamics of Concentration Fluctuations in Solutions of Weakly Attractive Globular Proteins ; The Journal of Physical Chemistry Letters, 6, 4470-4474 (2015).
[4] S. Bucciarelli, J. S. Myung, B. Farago, S. Das, G. A. Viegenthart, O. Holderer, R. G. Winkler, P. Schurtenberger, G. Gompper, and A. Stradner; Dramatic Influence of Attractions on Short-Time Protein Diffusion under Crowded Conditions ; Science Advances, 2, e1601432 (2016)
Patient-Reported Side Effects of Intradetrusor Botulinum Toxin Type A for Idiopathic Overactive Bladder Syndrome
Objective: The aim of the study was a prospective assessment of patient-reported side effects in an open-label study after intradetrusor botulinum toxin injections for idiopathic overactive bladder (OAB). Patients and Methods: Botulinum toxin A injection was performed in 56 patients with idiopathic OAB. Patients were followed up for 6 months concerning side effects and patients' satisfaction. Results: Different types of side effects were assessed such as dry mouth (19.6%), arm weakness (8.9%), eyelid weakness (8.9%), leg weakness (7.1%), torso weakness (5.4%), impaired vision (5.4%) and dysphagia (5.4%). In all cases, symptoms were mild and transient. Urological complications such as gross hematuria (17.9%), acute urinary retention (8.9%) and acute urinary tract infection (7.1%) were noticed. In all cases, acute urinary retention was transient and treated with temporary intermittent self-catheterization. There was no statistically significant correlation between dosage and observed side effects. Patients' satisfaction rate was high (71.4%). Conclusion: Intradetrusor injection of botulinum toxin was associated with a high rate of neurourological side effects. In general, side effects were transient, mild and did not require special treatment. Copyright (C) 2010 S. Karger AG, Base
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