476 research outputs found
Transport and diffusion in the embedding map
We study the transport properties of passive inertial particles in a
incompressible flows. Here the particle dynamics is represented by the
dissipative embedding map of area-preserving standard map which models
the incompressible flow. The system is a model for impurity dynamics in a fluid
and is characterized by two parameters, the inertia parameter , and the
dissipation parameter . We obtain the statistical characterisers of
transport for this system in these dynamical regimes. These are, the recurrence
time statistics, the diffusion constant, and the distribution of jump lengths.
The recurrence time distribution shows a power law tail in the dynamical
regimes where there is preferential concentration of particles in sticky
regions of the phase space, and an exponential decay in mixing regimes. The
diffusion constant shows behaviour of three types - normal, subdiffusive and
superdiffusive, depending on the parameter regimes. Phase diagrams of the
system are constructed to differentiate different types of diffusion behaviour,
as well as the behaviour of the absolute drift. We correlate the dynamical
regimes seen for the system at different parameter values with the transport
properties observed at these regimes, and in the behaviour of the transients.
This system also shows the existence of a crisis and unstable dimension
variability at certain parameter values. The signature of the unstable
dimension variability is seen in the statistical characterisers of transport.
We discuss the implications of our results for realistic systems.Comment: 28 pages, 14 figures, To Appear in Phys. Rev. E; Vol. 79 (2009
Effect of hydrogen on ground state structures of small silicon clusters
We present results for ground state structures of small SiH (2 \leq
\emph{n} \leq 10) clusters using the Car-Parrinello molecular dynamics. In
particular, we focus on how the addition of a hydrogen atom affects the ground
state geometry, total energy and the first excited electronic level gap of an
Si cluster. We discuss the nature of bonding of hydrogen in these
clusters. We find that hydrogen bonds with two silicon atoms only in SiH,
SiH and SiH clusters, while in other clusters (i.e. SiH,
SiH, SiH, SiH, SiH and SiH) hydrogen is bonded
to only one silicon atom. Also in the case of a compact and closed silicon
cluster hydrogen bonds to the cluster from outside. We find that the first
excited electronic level gap of Si and SiH fluctuates as a function
of size and this may provide a first principles basis for the short-range
potential fluctuations in hydrogenated amorphous silicon. Our results show that
the addition of a single hydrogen can cause large changes in the electronic
structure of a silicon cluster, though the geometry is not much affected. Our
calculation of the lowest energy fragmentation products of SiH clusters
shows that hydrogen is easily removed from SiH clusters.Comment: one latex file named script.tex including table and figure caption.
Six postscript figure files. figure_1a.ps and figure_1b.ps are files
representing Fig. 1 in the main tex
Evidence for directed percolation universality at the onset of spatiotemporal intermittency in coupled circle maps
We consider a lattice of coupled circle maps, a model arising naturally in
descriptions of solid state phenomena such as Josephson junction arrays. We
find that the onset of spatiotemporal intermittency (STI) in this system is
analogous to directed percolation (DP), with the transition being to an unique
absorbing state for low nonlinearities, and to weakly chaotic absorbing states
for high nonlinearities. We find that the complete set of static exponents and
spreading exponents at all critical points match those of DP very convincingly.
Further, hyperscaling relations are fulfilled, leading to independent controls
and consistency checks of the values of all the critical exponents. These
results lend strong support to the conjecture that the onset of STI in
deterministic models belongs to the DP universality class.Comment: Submitted to Physical Review
Prevalence of infections among 6-16 years old children attending a semi-rural school in Western Maharashtra, India
Background: Infections are an important cause of morbidity in rural India. Reports on the prevalence of infections in older childrenand their effects on growth are scarce. Objective: The objectives were to determine the prevalence of common infections among6-16 year old school-children in a semi-rural setting in Western India and to assess the influence of infections on the growth status ofthe children. Materials and Methods: This cross-sectional study was conducted in a semi-rural setting in a Zilla Parishad PrimarySchool, Karegaon, Maharashtra. 802 children (boys = 439), 6-16 years of age were assessed. Data on height, weight and infectionrelatedsymptoms reported by children (pre-tested, validated questionnaire) were collected. K-means cluster analysis was used to createthree clusters based on the severity of infections, and one-way analysis of variance with post-hoc Tukey’s multiple comparisons wasused to test the significance of differences in means of various characteristics of the subjects in three clusters. Results: 43% boys and49% girls reported symptoms of respiratory tract infections occasionally, and 28% boys and 27% girls complained of gastrointestinal(GI) infections occasionally. Children with more severe infections were more likely to be shorter and lighter; this was more marked ingirls. Conclusions: Rural school-going children (aged 6-16 years) suffer from high rates of infections, mainly upper respiratory tractinfections followed by GI tract infections
Coupled Maps on Trees
We study coupled maps on a Cayley tree, with local (nearest-neighbor)
interactions, and with a variety of boundary conditions. The homogeneous state
(where every lattice site has the same value) and the node-synchronized state
(where sites of a given generation have the same value) are both shown to occur
for particular values of the parameters and coupling constants. We study the
stability of these states and their domains of attraction. As the number of
sites that become synchronized is much higher compared to that on a regular
lattice, control is easier to effect. A general procedure is given to deduce
the eigenvalue spectrum for these states. Perturbations of the synchronized
state lead to different spatio-temporal structures. We find that a mean-field
like treatment is valid on this (effectively infinite dimensional) lattice.Comment: latex file (25 pages), 4 figures included. To be published in Phys.
Rev.
Incidence of Primary Mitochondrial Disease in Children Younger Than 2 Years Presenting With Acute Liver Failure
Background: Mitochondrial liver disease (MLD), and in particular mitochondrial DNA (mtDNA) depletion syndrome (MDS) is an important cause of acute liver failure (ALF) in infancy. Early and accurate diagnosis is important because liver transplantation (LT) is often contraindicated. It is unclear which methods are the best to diagnose MLD in the setting of ALF.
Objective: The aim of the study was to determine the incidence of MLD in children younger than 2 years with ALF and the utility of routine investigations to detect MLD.
Methods: Thirty-nine consecutive infants with ALF were admitted to a single unit from 2009 to 2011. All were extensively investigated using an established protocol. Genes implicated in mitochondrial DNA depletion syndrome were sequenced in all cases and tissue mtDNA copy number measured where available.
Results: Five infants (17%) had genetically proven MLD: DGUOK (n ¼ 2), POLG (n ¼ 2), and MPV17 (1). Four of these died, whereas 1 recovered. Two had normal muscle mtDNA copy number and 3 had normal muscle respiratory chain enzymes. An additional 8 children had low hepatic mtDNA copy number but pathogenic mutations were not detected. One of these developed fatal multisystemic disease after LT, whereas 5 who survived remain well without evidence of multisystemic disease up to 6 years later. Magnetic resonance spectroscopy did not distinguish between those with and without MLD.
Conclusions: Low liver mtDNA copy number may be a secondary phenomenon in ALF. Screening for mtDNA maintenance gene mutations may be the most efficient way to confirm MLD in ALF in the first 2 years of life
Synchronisation in Coupled Sine Circle Maps
We study the spatially synchronized and temporally periodic solutions of a
1-d lattice of coupled sine circle maps. We carry out an analytic stability
analysis of this spatially synchronized and temporally periodic case and obtain
the stability matrix in a neat block diagonal form. We find spatially
synchronized behaviour over a substantial range of parameter space. We have
also extended the analysis to higher spatial periods with similar results.
Numerical simulations for various temporal periods of the synchronized
solution, reveal that the entire structure of the Arnold tongues and the
devil's staircase seen in the case of the single circle map can also be
observed for the synchronized coupled sine circle map lattice. Our formalism
should be useful in the study of spatially periodic behaviour in other coupled
map lattices.Comment: uuencoded, 1 rextex file 14 pages, 3 postscript figure
Addition of tabulated equation of state and neutrino leakage support to IllinoisGRMHD
We have added support for realistic, microphysical, finite-temperature
equations of state (EOS) and neutrino physics via a leakage scheme to
IllinoisGRMHD, an open-source GRMHD code for dynamical spacetimes in the
Einstein Toolkit. These new features are provided by two new, NRPy+-based
codes: NRPyEOS, which performs highly efficient EOS table lookups and
interpolations, and NRPyLeakage, which implements a new, AMR-capable neutrino
leakage scheme in the Einstein Toolkit. We have performed a series of strenuous
validation tests that demonstrate the robustness of these new codes,
particularly on the Cartesian AMR grids provided by Carpet. Furthermore, we
show results from fully dynamical GRMHD simulations of single unmagnetized
neutron stars, and magnetized binary neutron star mergers. This new version of
IllinoisGRMHD, as well as NRPyEOS and NRPyLeakage, is pedagogically documented
in Jupyter notebooks and fully open source. The codes will be proposed for
inclusion in an upcoming version of the Einstein Toolkit.Comment: 20 pages, 9 figures. v2 matches PRD versio
Role of NAD(P)H Oxidase in Superoxide Generation and Endothelial Dysfunction in Goto-Kakizaki (GK) Rats as a Model of Nonobese NIDDM
Background: Cardiovascular disease is the leading cause of mortality in diabetics, and it has a complex etiology that operates on several levels. Endothelial dysfunction and increased generation of reactive oxygen species are believed to be an underlying cause of vascular dysfunction and coronary artery disease in diabetes. This impairment is likely the result of decreased bioavailability of nitric oxide (NO) within the vasculature. However, it is unclear whether hyperglycemia per se stimulates NADPH oxidase-derived superoxide generation in vascular tissue. Methods and Results: This study focused on whether NADPH oxidase-derived superoxide is elevated in vasculature tissue evoking endothelial/smooth muscle dysfunction in the hyperglycemic (16964 mg%) Goto-Kakizaki (GK) rat. By dihydroethidine fluorescence staining, we determined that aorta superoxide levels were significantly elevated in 9 month-old GK compared with age matched Wistar (GK; 19566%, Wistar; 10063.5%). Consistent with these findings, 10 26 mol/L acetylcholine-induced relaxation of the carotid artery was significantly reduced in GK rats compared with age matched Wistar (GK; 4167%, Wistar; 10065%) and measurements in the aorta showed a similar trend (p =.08). In contrast, relaxation to the NO donor SNAP was unaltered in GK compared to Wistar. Endothelial dysfunction was reversed by lowering of superoxide with apocynin, a specific Nox inhibitor. Conclusions: The major findings from this study are that chronic hyperglycemia induces significant vascular dysfunction i
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