Stark ladders as tunable far-infrared emitters

A superlattice of GaAs/Ga(1 – x)Al(x)As quantum wells forms a Stark ladder under the influence of a perpendicular electric field. A two level incoherent emitter system, formed by radiative intersubband transitions between adjacent wells, is investigated as a tunable far-infrared radiation source. Intersubband transition rates are calculated at 4, 77, and 300 K for applied fields from 0 to 40 kV cm(–1). It is shown that the quantum efficiency of the radiative emission reaches a maximum at low temperatures for a field of 32 kV cm(–1). Under these conditions the emission wavelength is 38 µm with an estimated power output of 1.1 mW. © 1998 American Institute of Physics

The colour-magnitude relations of ClJ1226.9+3332, a massive cluster of galaxies at z=0.89

(Abridged) The colour-magnitude relations of one of the most massive, high redshift clusters of galaxies known have been studied. Photometry has been measured in the V, R, I, z, F606W, F814W, J and K bands to a depth of K*+2.5 and spectroscopy confirms 27 K band selected cluster members. The V-K colours are equivalent to a rest-frame colour of ~2700A-J, and provide a very sensitive measure of star-formation activity. HST ACS imaging has been used to morphologically classify the galaxies. The cluster has a low early-type fraction compared to nearby clusters, with only 33% of the cluster members having types E or S0. The early-type member galaxies form a clear red-sequence in all colours. The scatter and slope of the relations show no evolution compared to the equivalent Coma cluster relations, suggesting the stellar populations are already very old. The normalisation of the relations has been compared to models based on synthetic stellar populations, and are most consistent with stellar populations forming at z>3. Some late-type galaxies were found to lie on the red-sequence, suggesting that they have very similar stellar populations to the early-types. These results present a picture of a cluster in which the early-type galaxies are all old, but in which there must be future morphological transformation of galaxies to match the early-type fraction of nearby clusters. In order to preserve the tight colour-magnitude relation of early-types seen in nearby clusters, the late-type galaxies must transform their colours, through the cessation of star-formation, before the morphological transformation occurs. Such evolution is observed in the late-types lying on the colour-magnitude relation.Comment: Accepted for publication in MNRAS. 14 pages, 5 figure

How Dry Are Red Mergers?

The focus of current research in galaxy evolution has increasingly turned to understanding the effect that mergers have on the evolution of systems on the red sequence. For those interactions purported to occur dissipationlessly (so called "dry mergers"), it would appear that the role of gas is minimal. However, if these mergers are not completely dry, then even low levels of gas may be detectable. The purpose of our study is to test whether early type galaxies with HI in or around them, or "wet" ellipticals, would have been selected as dry mergers by the criteria in van Dokkum (2005, AJ, 130, 2647). To that end, we examine a sample of 20 early types from the HI Rogues Gallery with neutral hydrogen in their immediate environs. Of these, the 15 brightest and reddest galaxies match the optical dry merger criteria, but in each case, the presence of HI means that they are not truly dry.Comment: 8 pages plus 1 table and 5 figures; accepted for publication in A

Correlation between X-ray Lightcurve Shape and Radio Arrival Time in the Vela Pulsar

We report the results of simultaneous observations of the Vela pulsar in X-rays and radio from the RXTE satellite and the Mount Pleasant Radio Observatory in Tasmania. We sought correlations between the Vela's X-ray emission and radio arrival times on a pulse by pulse basis. At a confidence level of 99.8% we have found significantly higher flux density in Vela's main X-ray peak during radio pulses that arrived early. This excess flux shifts to the 'trough' following the 2nd X-ray peak during radio pulses that arrive later. Our results suggest that the mechanism producing the radio pulses is intimately connected to the mechanism producing X-rays. Current models using resonant absorption of radio emission in the outer magnetosphere as a cause of the X-ray emission are explored as a possible explanation for the correlation.Comment: 6 pages, 5 figures, accepted by Ap

Intermediate and narrow band photometry of Epsilon Aurigae

Intermediate band blue (4530A), far red (7790A) and H-alpha intermediate and narrow band photoelectric observations of the peculiar, 27 year eclipsing binary, Epsilon Aurigae were made from December 1981 through the present (December 1984). BD +42 1170 served as the primary comparison star because of its angular proximity to the variable star. The analysis of this data along with other available photometry was undertaken to study the characteristics of the low amplitude, semi-regular light variations that appear inside and outside of eclipse. It appears that these short term light variations arise from nonradial pulsations of the luminous f supergiant in the system. Furthermore, the semi-regular light variations found for Epsilon Aurigae are similar to those found for other luminous A-F supergiants. Also, the preliminary results from the analyses of the light variations produced by the eclipse of the F-supergiant by the mysterious cooler component is discussed

Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer: the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial

Localised oesophageal cancer can be curatively treated with surgery (oesophagectomy) but the procedure is complex with a risk of complications, negative effects on quality of life and a recovery period of 6-9 months. Minimal-access surgery may accelerate recovery.The ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study aimed to establish the feasibility of, and methodology for, a definitive trial comparing minimally invasive and open surgery for oesophagectomy. Objectives were to quantify the number of eligible patients in a pilot trial; develop surgical manuals as the basis for quality assurance; standardise pathological processing; establish a method to blind patients to their allocation in the first week post surgery; identify measures of postsurgical outcome of importance to patients and clinicians; and establish the main cost differences between the surgical approaches.Pilot parallel three-arm randomised controlled trial nested within feasibility work.Two UK NHS departments of upper gastrointestinal surgery.Patients aged ≥ 18 years with histopathological evidence of oesophageal or oesophagogastric junctional adenocarcinoma, squamous cell cancer or high-grade dysplasia, referred for oesophagectomy or oesophagectomy following neoadjuvant chemo(radio)therapy.Oesophagectomy, with patients randomised to open surgery, a hybrid open chest and minimally invasive abdomen or totally minimally invasive access.The primary outcome measure for the pilot trial was the number of patients recruited per month, with the main trial considered feasible if at least 2.5 patients per month were recruited.During 21 months of recruitment, 263 patients were assessed for eligibility; of these, 135 (51%) were found to be eligible and 104 (77%) agreed to participate, an average of five patients per month. In total, 41 patients were allocated to open surgery, 43 to the hybrid procedure and 20 to totally minimally invasive surgery. Recruitment is continuing, allowing a seamless transition into the definitive trial. Consequently, the database is unlocked at the time of writing and data presented here are for patients recruited by 31 August 2014. Random allocation achieved a good balance between the arms of the study, which, as a high proportion of patients underwent their allocated surgery (69/79, 87%), ensured a fair comparison between the interventions. Dressing patients with large bandages, covering all possible incisions, was successful in keeping patients blind while pain was assessed during the first week post surgery. Postsurgical length of stay and risk of adverse events were within the typical range for this group of patients, with one death occurring within 30 days among 76 patients. There were good completion rates for the assessment of pain at 6 days post surgery (88%) and of the patient-reported outcomes at 6 weeks post randomisation (74%).Rapid recruitment to the pilot trial and the successful refinement of methodology indicated the feasibility of a definitive trial comparing different approaches to oesophagectomy. Although we have shown a full trial of open compared with minimally invasive oesophagectomy to be feasible, this is necessarily based on our findings from the two clinical centres that we could include in this small preliminary study.Current Controlled Trials ISRCTN59036820.This project was funded by the NIHR Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 20, No. 48. See the NIHR Journals Library website for further project information

Hypoalbuminaemia predicts outcome in adult patients with congenital heart disease

Background In patients with acquired heart failure, hypoalbuminaemia is associated with increased risk of death. The prevalence of hypoproteinaemia and hypoalbuminaemia and their relation to outcome in adult patients with congenital heart disease (ACHD) remains, however, unknown. Methods Data on patients with ACHD who underwent blood testing in our centre within the last 14 years were collected. The relation between laboratory, clinical or demographic parameters at baseline and mortality was assessed using Cox proportional hazards regression analysis. Results A total of 2886 patients with ACHD were included. Mean age was 33.3 years (23.6–44.7) and 50.1% patients were men. Median plasma albumin concentration was 41.0 g/L (38.0–44.0), whereas hypoalbuminaemia (<35 g/L) was present in 13.9% of patients. The prevalence of hypoalbuminaemia was significantly higher in patients with great complexity ACHD (18.2%) compared with patients with moderate (11.3%) or simple ACHD lesions (12.1%, p<0.001). During a median follow-up of 5.7 years (3.3–9.6), 327 (11.3%) patients died. On univariable Cox regression analysis, hypoalbuminaemia was a strong predictor of outcome (HR 3.37, 95% CI 2.67 to 4.25, p<0.0001). On multivariable Cox regression, after adjusting for age, sodium and creatinine concentration, liver dysfunction, functional class and disease complexity, hypoalbuminaemia remained a significant predictor of death. Conclusions Hypoalbuminaemia is common in patients with ACHD and is associated with a threefold increased risk of risk of death. Hypoalbuminaemia, therefore, should be included in risk-stratification algorithms as it may assist management decisions and timing of interventions in the growing ACHD population

'Selling it as a holistic health provision and not just about condoms ?' Sexual health services in school settings: current models and their relationship with sex and relationships education policy and provision

In this article we discuss the findings from a recent study of UK policy and practice in relation to sexual health services for young people, based in - or closely linked with - schools. This study formed part of a larger project, completed in 2009, which also included a systematic review of international research. The findings discussed in this paper are based on analyses of interviews with 51 service managers and questionnaire returns from 205 school nurses. Four themes are discussed. First, we found three main service permutations, in a context of very diverse and uneven implementation. Second, we identified factors within the school context that shaped and often constrained service provision; some of these also have implications for sex and relationships education (SRE). Third, we found contrasting approaches to the relationship between SRE input and sexual health provision. Fourth, we identified some specific barriers that need to be addressed in order to develop 'young people friendly' services in the school context. The relative autonomy available to school head teachers and governors can represent an obstacle to service provision - and inter-professional collaboration - in a climate where, in many schools, there is still considerable ambivalence about discussing 'sex' openly. In conclusion, we identify areas worthy of further research and development, in order to address some obstacles to sexual health service and SRE provision in schools

Type I D-branes in an H-flux and twisted KO-theory

Witten has argued that charges of Type I D-branes in the presence of an H-flux, take values in twisted KO-theory. We begin with the study of real bundle gerbes and their holonomy. We then introduce the notion of real bundle gerbe KO-theory which we establish is a geometric realization of twisted KO-theory. We examine the relation with twisted K-theory, the Chern character and provide some examples. We conclude with some open problems.Comment: 23 pages, Latex2e, 2 new references adde

Advance telephone calls ahead of reminder questionnaires increase response rate in non-responders compared to questionnaire reminders only : The RECORD phone trial

Peer reviewedPublisher PD