The connection between the radio jet and the gamma-ray emission in the radio galaxy 3C 120

We present the analysis of the radio jet evolution of the radio galaxy 3C 120 during a period of prolonged gamma-ray activity detected by the Fermi satellite between December 2012 and October 2014. We find a clear connection between the gamma-ray and radio emission, such that every period of gamma-ray activity is accompanied by the flaring of the mm-VLBI core and subsequent ejection of a new superluminal component. However, not all ejections of components are associated with gamma-ray events detectable by Fermi. Clear gamma-ray detections are obtained only when components are moving in a direction closer to our line of sight.This suggests that the observed gamma-ray emission depends not only on the interaction of moving components with the mm-VLBI core, but also on their orientation with respect to the observer. Timing of the gamma-ray detections and ejection of superluminal components locate the gamma-ray production to within almost 0.13 pc from the mm-VLBI core, which was previously estimated to lie about 0.24 pc from the central black hole. This corresponds to about twice the estimated extension of the broad line region, limiting the external photon field and therefore suggesting synchrotron self Compton as the most probable mechanism for the production of the gamma-ray emission. Alternatively, the interaction of components with the jet sheath can provide the necessary photon field to produced the observed gamma-rays by Compton scattering.Comment: Already accepted for publication in The Astrophysical Journa

Genetic Predictors of Malignancy: a Literature Review

The review covers recent research on cancer as a genetic disease manifesting both sporadically and in germline through variant genomic mutations or DNA rearrangements. This change can be point mutations, chromosomal aberrations or hypermethylation leading to DNA repair failures. Defects in tumour suppressor genes (BRCA1, BRCA2, CHEK2, PTCH1, etc.) underly hereditary predisposition to breast cancer (BC) and ovarian cancer (OC) due to genome instability. Studying somatic mutations is key to the understanding of carcinogenesis mechanisms and finding apt therapies. Heterogeneity of cancers renders the tumour mutation profiling uneasy. The treatment choice and efficacy in BC and OC depends on homologous recombination defects in tumour cells usually imposed by damaged BRCA1/2 genes. CHEK2- associated neoplasms account for most hereditary BCs linked to flaws in the DNA repair machinery. Overexpression of the PTCH1 protein is the target in breast, lung, ovarian, colonic cancers, etc.Genetic research has fundamentally altered our understanding of the aetiology and pathogenesis of human malignancy. The molecular cancer phenotype is of paramount importance in the disease prognosis and treatment personalisation

Multiwavelength observations of the blazar BL Lacertae: a new fast TeV γ-ray flare

Proceedings of the 35th International Cosmic Ray Conference (ICRC 2017), Busan (South Korea). Published in Proceeding of Science.Observations of fast TeV γ-ray flares from blazars reveal the extreme compactness of emitting regions in blazar jets. Combined with very-long-baseline radio interferometry measurements, they probe the structure and emission mechanism of the jet. We report on a fast TeV γ-ray flare from BL Lacertae observed by VERITAS, with a rise time of about 2.3 hours and a decay time of about 36 minutes. The peak flux at >200 GeV measured with the 4-minute binned light curve is (4.2±0.6)×10−6photonsm−2s−1, or ∼180% the Crab Nebula flux. Variability in GeV γ-ray, X-ray, and optical flux, as well as in optical and radio polarization was observed around the time of the TeV γ-ray flare. A possible superluminal knot was identified in the VLBA observations at 43 GHz. The flare constrains the size of the emitting region, and is consistent with several theoretical models with stationary shocks

Freely decaying weak turbulence for sea surface gravity waves

We study numerically the generation of power laws in the framework of weak turbulence theory for surface gravity waves in deep water. Starting from a random wave field, we let the system evolve numerically according to the nonlinear Euler equations for gravity waves in infinitely deep water. In agreement with the theory of Zakharov and Filonenko, we find the formation of a power spectrum characterized by a power law of the form of $|{\bf k}|^{-2.5}$.Comment: 4 pages, 3 figure

EVOLUTION OF THE MAGNETIC PROPERTIES OF TWO-DIMENSIONAL Fe3GeTe2 UNDER STRAIN

In this work we study the evolution of magnetic properties, magnetization, and magnon spectra of Fe3GeTe2 changes under in-plane biaxial strain. We found that moderate tensile strain significantly increases Curie temperature, while compressive one destroys FM order.This work was supported by the Russian Science Foundation Grant 21-72-10136