Implant supported cantilevered fixed dental rehabilitations in partially edentulous patients : systematic review of the literature. Part I

Objectives: To investigate in which clinical situations a cantilever fixed implant supported restorations can be a treatment alternative and which complications are reported. Materials and Methods: Two operators screened the literature (MEDLINE, EMBASE) and performed a hand search on the main journals dealing with implantology and prosthetics until 31 December 2017. Only articles that considered cantilever implant fixed restorations with at least 10 patients and with a mean follow-up of at least 5\ua0year were selected. The outcome variables were survival of implants and prosthesis, mechanical, technical and biological complications, marginal bone loss. The review was performed according to the PRISMA statements. Risk of bias assessment was evaluated. Failure and complication rates were analysed using random effect Poisson regression models to obtain summary estimate of 5- and 10-year survival and complication rates. Results: A total of nine papers were selected for partially edentulous patients and reported high survival rate of the prosthesis. The estimated survival rate for 5\u201310\ua0years was calculated to be 98.4% for the implants and 99.2% for the rehabilitations. Mechanical, technical and biological complications were reported with a cumulative 5\u201310\ua0years complication rate of 28.66% and 26.57% for the patients and for the prosthesis, respectively. Two papers for single implant supporting 2-unit cantilever were not sufficient to draw conclusions. Conclusions: There is evidence that cantilever can be successful treatment in partially edentulous patients. In two adjacent edentulous sites, data are not yet sufficient

Sting Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes.

This article is intended to show how Sting Millennium Suite of programs can be useful in the study of protein structure and analysis of its function, emphasizing recent improvement introduced to SMS. The program has extensive built-in instructions and detailed easy-to-use help which user is invited to consult before and during SMS use.Na publicação: Paula R Kuser

STING Millennium: a web-based suite of programs for comprehensive and simultaneous analysis of protein structure and sequence.

Sting Millennium suite intrinsics. SMS organization. Sting Millennium Modes. Sting Millennium Modules. Millennium Features. Example of Sting Millennium Application.Na publicação: Paula R. Kuser

Influence of tree species richness on tree growth and intrinsic water-use efficiency after drought in tree plantations in north-eastern Italy

Recent studies have highlighted that higher species richness can increase the resistance and/or the resilience to disturbances and stresses. The present study quantifies the overall tree species richness effect on growth and intrinsic water-use efficiency (iWUE) in three target tree species (i.e. Fraxinus excelsior, Juglans spp. and Prunus avium) after drought in six deciduous plantations in the Friuli-Venezia Giulia plain, North-eastern Italy. Planting densities, management, climatic and soil characteristics were the same at all the plantations. Stands differed only for their total surface area and for their total tree species richness (3, 4, 6, 7, 8 and 9). We double-sampled 15 dominant trees for each of the three target species, we measured tree-ring width, and we removed age-related trends using a detrending function. We selected 2006 as the driest year at the sites and 2014 as the reference year using the De Martonne Index. For both years, we measured \u3b413C signature in tree rings to calculate iWUE. Tree species richness had a positive effect on the response to drought both in terms of normalized ring width and iWUE, but only at a lower number of consociated species (< 5), when facilitation and/or complementarity mechanisms prevailed. Instead, negative responses were typical at higher levels ( 65 5), when competition was the dominant process within the stand. Moreover, species richness had no effect on tree growth in 2014, maybe because either competition or complementarity processes did not occur, or these processes could cancel out each other, when environmental conditions were not limiting

Implant-supported cantilevered fixed dental rehabilitations in fully edentulous patients : Systematic review of the literature. Part II

AIM: To investigate fully edentulous patients rehabilitated with cantilever-fixed implant-supported restorations and to analyse which complications are reported for this type of treatment. MATERIALS AND METHODS: Two operators screened the literature (MEDLINE, EMBASE) and performed a hand search on the main journals dealing with implantology and prosthetics until 31 December 2017. Only articles that considered cantilever implant-fixed restorations with at least 10 patients and with a mean follow-up of at least 5 years were selected. The outcome variables were survival of implants and prosthesis, mechanical, technical and biological complications, marginal bone loss. The review was performed according to the PRISMA statements. The risk of bias was evaluated for each article. Failure and complication rates were analysed using random effect Poisson regression models to obtain summary estimate of 5- and 10-year survival and complication rates. RESULTS: Fourteen papers for fully edentulous patients were selected. The estimated 5 to 10 years survival rate was calculated to be 99.00% and 96.7% for the implants and the prosthesis, respectively. A total of 299 complications (technical and biological) were reported with a cumulative 5-10 years complication rate of 44.41% and 39.46% for the patients and for the prosthesis, respectively. CONCLUSIONS: There is evidence that cantilever can be successful treatment in fully edentulous patients

Stratification of prosthetic complications by manufacturer in implant-supported restorations with a 5 years&#8217; follow-up: systematic review of the literature

INTRODUCTION: Prosthetic complications on implant-supported restorations have been documented in several papers published in the literature. Several manufacturers are present on the market but results are often cumulated and may thus be misleading. The objective of the present review is to assess the prosthetic complications of implant-supported restorations with particular interest of the results obtained with prostheses from different manufacturers. EVIDENCE ACQUISITION: A manual search of Medline/PubMed was carried out up to June 2016, yielding a total of 6832 articles, which were narrowed down to 1450, then 347 abstracts to include 55 papers after full text reading. Papers with at least 5 years of follow-up reporting on prosthetic complications of single and fixed partial prosthesis were included. Prosthetic complications were divided into mechanical and technical complications, and reported in a table. EVIDENCE SYNTHESIS: Overall 14.4% of prosthetic complication was found for a total of 6623 restorations followed for an average of 7.4 years (range 5-16 years). Results where then sorted and compared. Single crowns were affected by 1.4% of mechanical complications and 10.9% of technical complications after a mean of 7.4 years. Fixed partial prosthesis were affected by 2.5% of mechanical complications and 18% of technical complications. Screw-retained and cemented restorations were calculated to have a 5 years rate of complications of 21.2% and 9.3%, respectively, which demonstrated a statistically difference with fisher exact test with P<0.1. Only 3 manufacturers presented more than 10 articles and were directly compared with Fisher's exact test with P<0.1. The incidence of overall complications was estimated to be after 5 years of 11.2%, 10.8% and 13.8% for Straumann, Nobel, and Astratech, respectively, but dividing results in mechanical and technical complications, gave different results. Straumann was estimated to have less mechanical complications after 5 years in respect to Nobel and Astratech, but the three were similar for technical complications. CONCLUSIONS: although studies present very different material and methods and do not report all data, some conclusions can be made. The difference between mechanical complications lead the authors to suppose that there might be a difference in results obtained by different implant abutment connections. It is also noticed that all papers were published by expert clinicians and universities research centers that apply rigid surgical and prosthetic protocols and use original abutments

Role of photosynthesis and stomatal conductance on the long-term rising of intrinsic water use efficiency in dominant trees in three oldgrowth forests in Bosnia-Herzegovina and Montenegro

Old-growth forests have an important role in maintaining animal and plant diversity, are important carbon (C) reservoirs and are privileged sites to study long-term plant physiological responses, long-term forest dynamics and climate change impact on forest ecosystems. Several studies have highlighted how old-living trees undergo age-related declines with hydraulic limitations and reduction in photosynthesis, though some recent works have suggested that such a decline is not always observed. Our study aims at understanding the role of atmospheric CO2 increase on tree C uptake and stomatal conductance (gs) in old-living trees by analysing the long-term patterns of tree growth and intrinsic water use efficiency (iWUE) in three old-growth forests in the Balkans (Bosnia-Herzegovina and Montenegro), using dendrochronology and isotopic analysis. We hypothesised a long-term increase in iWUE in the studied old-growth forests, mostly related to enhanced photosynthesis rather than reduced stomatal conductance. Tree cores were sampled from dominant silver fir (Abies alba Mill.) trees in each forest. Tree-ring widths were measured and basal area increments (BAI) were assessed for each sampled tree and, from the six longest chronologies, five decades were chosen for cellulose extraction, its isotopic analysis (\u3b413C, \u3b418O), iWUE and leaf water18O evaporative enrichment above the source water (\u39418OL) determination. We observed a continuous and significant increase in iWUE from 1800 to 2010 in the sampled dominant trees at all the three old-growth forests. Our BAI data and our estimates of \u39418OL across the study period support the idea that enhanced photosynthesis rather than reduced stomatal conductance is the major driver of the measured iWUE increase. Thus, our results support some recent findings challenging the hypothesis that iWUE in forests is primarily the result of a CO2-induced reduction in stomatal conductance as well as the so called hydraulic limitation hypothesis