A meta-narrative review of electronic patient records

This session comprises four papers that consider how systematic review methods may be developed in order to make the best use of complex evidence in education and health. The methods and approaches reflected upon in these papers are not drawn from a single research tradition, but share a common goal of broadening the methodological scope of systematic reviews and better understanding the utilisation of knowledge produced in this way. The first paper (Henry Potts) reports an ongoing review using a meta-narrative approach to make sense of the diverse sources of knowledge regarding electronic patient records. The review method has stressed the importance of understanding knowledge from within the research tradition in which it was produced; it is argued that this has important implications for the way that evidence is utilised in the policy making process. The second paper (Geoff Wong) reflects upon the experience of using an explicit realist approach in the synthesis of the evidence in Internet based learning. This realist synthesis offers a method of making sense of the highly heterogeneous and context dependent evidence which exists in this field thus enabling greater insights into what makes such educational interventions ‘work’. The third paper (Rod Sheaff) reports a review of the predominantly qualitative research literature on organisational structures and their impacts upon policy outcomes in health systems. A scoping study found 14389 relevant papers of which 1568 were selected for review. These studies were very variable in the amount and quality of the qualitative data, hence 'evidence', which they reported. The paper describes an attempt to adapt realist methods so as to synthesise such bodies of research in ways which take account of this variation in the strength of qualitative evidence. The fourth paper (Mark Pearson) draws upon the work of Donald Campbell and colleagues in order to gain a fuller understanding of how systematic reviews are utilised in the policy making process. It is argued that interpretive approaches to understanding policy making (such as rhetorical analysis) need to be tempered with a more nuanced understanding of research validity. The case is made that interpretive approaches not only can, but should, be melded with research validity to increase understanding of the policy making process

X-ray Observations of Parsec-Scale Tails behind Two Middle-Aged Pulsars

Chandra and XMM-Newton resolved extremely long tails behind two middle-aged pulsars, J1509-5850 and J1740+1000. The tail of PSR J1509-5850 is discernible up to 5.6' from the pulsar (6.5 pc at a distance of 4 kpc), with a flux of 2*10^{-13} erg s^{-1} cm^{-2} in 0.5-8 keV. The tail spectrum fits an absorbed power-law (PL) model with the photon index of 2.3\pm0.2, corresponding to the 0.5-8 keV luminosity of 1*10^{33} ergs s^{-1}, for n_H= 2.1*10^{22} cm^{-2}. The tail of PSR J1740+1000 is firmly detected up to 5' (2 pc at a 1.4 kpc distance), with a flux of 6*10^{-14} ergs cm^{-2} s^{-1} in 0.4-10 keV. The PL fit yields photon index of 1.4-1.5 and n_H=1*10^{21} cm^{-2}. The large extent of the tails suggests that the bulk flow in the tails starts as mildly relativistic downstream of the termination shock, and then gradually decelerates. Within the observed extent of the J1509-5850 tail, the average flow speed exceeds 5,000 km s^{-1}, and the equipartition magnetic field is a few times 10^{-5} G. For the J1740+1000 tail, the equipartition field is a factor of a few lower. The harder spectrum of the J1740+1000 tail implies either less efficient cooling or a harder spectrum of injected electrons. For the high-latitude PSR J1740+1000, the orientation of the tail on the sky shows that the pulsar is moving toward the Galactic plane, which means that it was born from a halo-star progenitor. The comparison between the J1509 and J1740 tails and the X-ray tails of other pulsars shows that the X-ray radiation efficiency correlates poorly with the pulsar spin-down luminosity or age. The X-ray efficiencies of the ram-pressure confined pulsar wind nebulae (PWNe) are systematically higher than those of PWNe around slowly moving pulsars with similar spin-down parameters.Comment: 14 pages, 16 figures and 5 table

A Study of Non-Neutral Networks with Usage-based Prices

Hahn and Wallsten wrote that network neutrality "usually means that broadband service providers charge consumers only once for Internet access, do not favor one content provider over another, and do not charge content providers for sending information over broadband lines to end users." In this paper we study the implications of non-neutral behaviors under a simple model of linear demand-response to usage-based prices. We take into account advertising revenues and consider both cooperative and non-cooperative scenarios. In particular, we model the impact of side-payments between service and content providers. We also consider the effect of service discrimination by access providers, as well as an extension of our model to non-monopolistic content providers

The determination and distribution of iodate in South Atlantic waters

A novel method has been developed for the precise determination of iodate in sea water and the technique has been applied to samples from two stations in the Argentine Basin and one station in the Angola Basin. The method involves acidification of the sea water sample in the presence of excess iodjde in order to form the tri-iodide ion and measurement of the absorbance of this ion in a spectrophotometric titration cell...

Perspective on Quark Mass and Mixing Relations

Recent data indicate that $V_{ub}\cong \lambda^4 \cong (0.22)^4$, while $m_t$ seems to be $174$ GeV. The relations $m_d/m_s\sim m_s/m_b \sim \delta \sim \lambda^2 \simeq \vert V_{cb}\vert$ and $m_u/m_c\sim m_c/m_t \sim \delta^2 \sim \lambda^4 \sim \vert V_{ub}\vert$ suggest that %a plausible clean separation of the %origin of the quark mixing matrix: the down type sector is responsible for $\vert V_{us}\vert$ and $\vert V_{cb}\vert$, while $V_{ub}$ comes from the up type sector. Five to six parameters might suffice to account for the ten quark mass and mixing parameters, resulting in specific power series representations for the mass matrices. In this picture, $\delta$ seems to be the more sensible expansion parameter, while $\lambda \cong \sqrt{m_d/m_s} \sim \sqrt{\delta}$ is tied empirically to $(M_d)_{11} = 0$.Comment: 10 pages, ReVtex, no figure

Perturbative Wilson loops from unquenched Monte Carlo simulations at weak couplings

Perturbative expansions of several small Wilson loops are computed through next-to-next-to-leading order in unquenched lattice QCD, from Monte Carlo simulations at weak couplings. This approach provides a much simpler alternative to conventional diagrammatic perturbation theory, and is applied here for the first time to full QCD. Two different sets of lattice actions are considered: one set uses the unimproved plaquette gluon action together with the unimproved staggered-quark action; the other set uses the one-loop-improved Symanzik gauge-field action together with the so-called ``asqtad'' improved-staggered quark action. Simulations are also done with different numbers of dynamical fermions. An extensive study of the systematic uncertainties is presented, which demonstrates that the small third-order perturbative component of the observables can be reliably extracted from simulation data. We also investigate the use of the rational hybrid Monte Carlo algorithm for unquenched simulations with unimproved-staggered fermions. Our results are in excellent agreement with diagrammatic perturbation theory, and provide an important cross-check of the perturbation theory input to a recent determination of the strong coupling $\alpha_{\bar{\rm MS}}(M_Z)$ by the HPQCD collaboration.Comment: 14 pages, 8 figure

Potential Models and Lattice Gauge Current-Current Correlators

We compare current-current correlators in lattice gauge calculations with correlators in different potential models, for a pseudoscalar charmonium in the quark-gluon plasma. An important ingredient in the evaluation of the current-current correlator in the potential model is the basic principle that out of the set of continuum states, only resonance states and Gamow states with lifetimes of sufficient magnitudes can propagate as composite objects and can contribute to the current-current correlator. When the contributions from the bound states and continuum states are properly treated, the potential model current-current correlators obtained with the potential proposed in Ref. [11] are consistent with the lattice gauge correlators. The proposed potential model thus gains support to be a useful tool to complement lattice gauge calculations for the study of $Q\bar Q$ states at high temperatures.Comment: 18 pages, 4 figures, to be published in Physcial Review

Asymptotic corrections to the eigenvalue density of the GUE and LUE

We obtain correction terms to the large N asymptotic expansions of the eigenvalue density for the Gaussian unitary and Laguerre unitary ensembles of random N by N matrices, both in the bulk of the spectrum and near the spectral edge. This is achieved by using the well known orthogonal polynomial expression for the kernel to construct a double contour integral representation for the density, to which we apply the saddle point method. The main correction to the bulk density is oscillatory in N and depends on the distribution function of the limiting density, while the corrections to the Airy kernel at the soft edge are again expressed in terms of the Airy function and its first derivative. We demonstrate numerically that these expansions are very accurate. A matching is exhibited between the asymptotic expansion of the bulk density, expanded about the edge, and the asymptotic expansion of the edge density, expanded into the bulk.Comment: 14 pages, 4 figure