Soliton absorption spectroscopy

We analyze optical soliton propagation in the presence of weak absorption lines with much narrower linewidths as compared to the soliton spectrum width using the novel perturbation analysis technique based on an integral representation in the spectral domain. The stable soliton acquires spectral modulation that follows the associated index of refraction of the absorber. The model can be applied to ordinary soliton propagation and to an absorber inside a passively modelocked laser. In the latter case, a comparison with water vapor absorption in a femtosecond Cr:ZnSe laser yields a very good agreement with experiment. Compared to the conventional absorption measurement in a cell of the same length, the signal is increased by an order of magnitude. The obtained analytical expressions allow further improving of the sensitivity and spectroscopic accuracy making the soliton absorption spectroscopy a promising novel measurement technique.Comment: 9 pages, 7 figures

Efficient half-harmonic generation of three-optical-cycle mid-IR frequency comb around 4 µm using OP-GaP

We report a broadband mid-infrared frequency comb with three-optical-cycle pulse duration centered around 4.2 µm, via half-harmonic generation using orientation-patterned GaP (OP-GaP) with ~43% conversion efficiency. We experimentally compare performance of GaP with GaAs and lithium niobate as the nonlinear element, and show how properties of GaP at this wavelength lead to generation of the shortest pulses and the highest conversion efficiency. These results shed new light on half-harmonic generation of frequency combs, and pave the way for generation of short-pulse intrinsically-locked frequency combs at longer wavelengths in the mid-infrared with high conversion efficiencies

Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors

Various 4′-R-substituted phenyl azacyclic allenes were synthesized in good yields, and their thermal transformations were studied. For the first time, the obtained rearrangement products—new N-bridged cyclopenta[a]indenes, and the corresponding parent allenes were evaluated as potential inhibitors of acetyl- and butyrylcholinesterase. Among the tested compounds, the allene derivative 2g proved to competitively inhibit human AChE with inhibition constant value (Ki) in the low micromolar range. Graphic abstract: [Figure not available: see fulltext.

The origin of intergalactic thermonuclear supernovae

The population synthesis method is used to study the possibility of explaining the appreciable fraction (20^+12_15%) of the intergalactic (no-host) type Ia supernovae observed in galaxy clusters (Gal-Yam ete al. 2003) by binary whote dwarf merginngs in the cores of globular clusters. In a typical globular cluster, the number of merging double white dwarfs is fount to be smaller than 10^{-13} per year per average cluster star during the entire evolution of the cluster, which is a factor of 3 higher than in a Milky-Way-type galaxy. From 5 to 30% of the merging white dwarfs are dynamically expelled from the cluster with barycenter velocities up to 150 km/s. SN Ia explosions during the mergers of binary white dwarfs in dense star clusters may account for \sim 1% of the total rate of SN Ia in the central parts of galaxy clusters if the baryon mass fraction in such star clusters is \sim 0.3%.Comment: 8 pages, 3 figs. Astronomy Letters (in press

Modeling of the Tax Base for Property Tax and Income Forecasting for the Irkutsk Region

Forecasting tax revenues is of particular importance for the treasuries of Russia’s constituent regions and municipalities. Such revenues are directly related to the regions’ development prospects on the basis of realizing their own potential, including taxation. The relevance of this work is determined by the requirement to develop the socio-economic territories of municipalities using modern approaches in the field of fiscal forecasting. Property taxes, including corporate property tax, which is one of the stable sources of revenue, have a significant impact on the tax potential of regional and local budgets. The aim of this work is to determine the impact of socio-economic indicators on the tax base formed by corporate property at a municipal level in Irkutsk Region. To achieve the goal, we apply the econometric methods of research, mainly regression analysis. The idea of this approach is to select independent factors (among socio-economic indicators) that affect the value of the resulting, or dependent, variable (the tax base). The investigation uses the following empirical basis: the statistical tax reporting data presented in the “Report on the tax base and the structure of accruals on corporate property tax” in the context of municipal entities as of 01.01.2014 and indicators of municipal entities of the Federal State Statistics Service for 2013. Six economic-mathematical models of multiple regression were constructed during the research. After checking their adequacy, the authors prefered a linear model, based on which point and interval forecasts are constructed. The numerical experiments led to a conclusion that the initial data are not homogeneous, which, apparently, is determined by the large area of Irkutsk Region, the uneven distribution of natural resources and the remoteness of some municipalities. These facts justify grouping municipalities into clusters in order to increase the homogeneity in each group and the adequacy of the model. The authors plan to apply this approach in their further research. The article is devoted to the modeling of the property tax base of organizations and forecasting of tax revenues in the municipalities of Irkutsk Region. The relevance of the investigation is determined by the necessity to improve tax forecasting in the Russian Federation. At the first stage of the study, the factors influencing the formation of the tax base were selected. Using the data for 2013, six various mathematical models of multiple regression are constructed. In the preliminary analysis, the following two best models were selected: linear and semilogarithmic ones. In the paper, the authors prefer a linear model, which is used for the point and interval forecasting. Basing on the selected model, a point and interval forecasts are established for the tax base for the property tax of organizations.Прогнозирование налоговых доходов имеет особое значение для бюджетов субъектов Российской Федерации и местных бюджетов и напрямую связано с возможностью развития регионов на основе реализации собственного потенциала, в том числе и налогового. Актуальность данной работы обусловлена необходимостью развития современных подходов в области бюджетно-налогового прогнозирования с целью развития социально-экономических территорий муниципальных образований. Существенное влияние на налоговый потенциал региональных и местных бюджетов оказывают имущественные налоги, в том числе налог на имущество организаций, который является одним из стабильных источников дохода. Цель работы состоит в определении влияния социально-экономических показателей на налоговую базу по имуществу организаций на уровне муниципальных образований Иркутской области. Для достижения цели применяются эконометрические методы исследования, главным образом регрессионный анализ. Идея этого подхода состоит в отборе независимых факторов (из числа социально-экономических показателей), влияющих на величину результирующей, или зависимой, переменной (налоговой базы). В качестве эмпирической базы использовались данные статистической налоговой отчетности № 5-НИО «Отчет о налоговой базе и структуре начислений по налогу на имущество организаций» в разрезе муниципальных образований по состоянию на 01.01.2014 и показателей муниципальных образований Федеральной службы государственной статистики за 2013 г. В процессе исследования построено шесть экономико-математических моделей множественной регрессии. После проверки их на адекватность авторы отдают предпочтение линейной модели, на основе которой строятся точечный и интервальный прогнозы. Проведенные расчеты привели к выводу о неоднородности исходных данных, которая, по всей видимости, определяется большой площадью Иркутской области, неравномерным распределением природных ресурсов и труднодоступностью отдельных муниципальных образований. Указанные факты обосновывают разбиение на кластеры муниципальных образований с целью повышения однородности в каждой группе и адекватности модели. Авторы планируют применить такой подход в своих дальнейших исследованиях. Основные положения: построено несколько эконометрических моделей зависимости налоговой базы по налогу на имущество организаций от факторов, влияющих на ее формирование; проведен анализ качества каждой модели и выбрана наилучшая из них; на основе отобранной модели построен точечный и интервальные прогнозы налоговой база по налогу на имущество организаций

Athletes’ Relationships with Training Scale (ART)

The Athletes’ Relationships with Training Scale (ART)* is a self-report measure of unhealthy training behaviors and beliefs in athletes. The ART was designed for use by clinicians and athletic trainers to help identify athletes who are engaging in unhealthy training practices which could be associated with an eating disorder. The ART may also be helpful for tracking clinical outcomes in athletes with eating disorders who are receiving treatment. This record contains the 15-item ART as well as scoring instructions and guidelines for interpreting total scores

The Athletes\u27 Relationships with Training Scale (ART): A Self-Report Measure of Unhealthy Training Behaviors Associated with Eating Disorders

Objective: Several studies indicate that eating-disorder (ED) psychopathology is elevated in athletes compared to non-athletes. The assessment of excessive exercise among athletes is a challenge because, compared to non-athletes, athletes are required to train at higher intensities and for longer periods of time. However, individuals participating in competitive sports are still susceptible to unhealthy physical-activity patterns. Most ED assessments were developed and normed in non-athlete samples and, therefore, do not capture the nuances of athletes\u27 training experiences. The purpose of the current study was to develop and validate a clinically useful, self-report measure of unhealthy training behaviors and beliefs in athletes, the Athletes\u27 Relationships with Training Scale (ART). Method: The initial item pool was administered to N = 267 women collegiate athletes who were participating in an ED prevention program study and N = 65 women athletes who were in ED treatment. Results: Factor analyses indicated the ART had a four-factor structure. Factorial and construct validity of the ART were demonstrated. ART scores significantly predicted health care utilization and differed between athletes with an ED versus athletes without an ED. For athletes in ED treatment, ART scores significantly decreased from treatment admission to discharge. Discussion: The ART showed evidence of strong psychometric properties and clinical utility. The ART could be helpful for clinicians and athletic trainers to help gauge whether athletes are engaging in unhealthy training practices that may warrant clinical attention and for tracking clinical outcomes in athletes with EDs who are receiving treatment

Association of the AGT, ACE, NOS3 polymorphism with subclinical arterial wall changes and cardiovascular diseases risk factors

Background. Renin-Angiotensin-Aldosterone System activation (RAAS) and nitric oxide (NO) reduction lead to the changes in the arterial wall, which, in turn, create a favourable environment for the development of cardiovascular diseases (CVD). There is only limited knowledge of the influence of proteins participating in the RAAS activation and providing NO bioavailability on the parameters of the arterial wall state (pulse wave velocity (PWV), carotid artery intima-media thickness (cIMT), endothelium-dependent vasodilation (EDVD), presence of atherosclerotic plaques) and risk factors of CVD. Aim. Finding the association between the AGT, ACE, NOS3 polymorphism and PWV, cIMT, EDV, presence of atherosclerotic plaques and risk factors of CVD in healthy subjects. Methods. Using intergroup analysis and models of multiple logistic regression, we examined the association of AGT с.521СТ polymorphism, AСE InsDel polymorphism, NOS3 с.894GT polymorphism with arterial wall changes and risk factors of CVD in 160 healthy people of different ages. Results. The CT genotype of AGT с.521СТ polymorphism was associated with lower levels of systolic blood pressure (BP) (p=0.013) and central systolic BP (p=0.029), higher level of Insulin-Like Growth Factor (IGF) (p=0.027). The DD genotype of ACE InsDel polymorphism was associated with a higher waist/hip ratio (p=0.044), lower level of high density lipoprotein cholesterol (p=0.01), lower index of EDVD (p=0.042), higher incidence ofendothelial dysfunction (ED) (p=0.026). The GG genotype of NOS3 с.894GT polymorphism was associated with higher levels of central systolic BP (p=0.022) and central mean BP (p=0.033), total cholesterol (p=0.025), low density lipoprotein cholesterol (p=0.014) and IGF (p=0.042), higher incidence of ED (p=0.007), albuminuria (p=0.032) and insulin resistance (p=0.03). Conclusion. We have found the association of the AСE and NOS3 polymorphism with endothelial dysfunction and the metabolic status

Thermonuclear Burning Regimes and the Use of SNe Ia in Cosmology

The calculations of the light curves of thermonuclear supernovae are carried out by a method of multi-group radiation hydrodynamics. The effects of spectral lines and expansion opacity are taken into account. The predictions for UBVI fluxes are given. The values of rise time for B and V bands found in our calculations are in good agreement with the observed values. We explain why our results for the rise time have more solid physical justification than those obtained by other authors. It is shown that small variations in the chemical composition of the ejecta, produced in the explosions with different regimes of nuclear burning, can influence drastically the light curve decline in the B band and, to a lesser extent, in the V band. We argue that recent results on positive cosmological constant Lambda, found from the high redshift supernova observations, could be wrong in the case of possible variations of the preferred mode of nuclear burning in the earlier Universe.Comment: 20 pages, 5 figures, presented at the conference "Astronomy at the Eve of the New Century", Puschino, May 17-22, 1999. A few references and a table added, typos correcte

Influence of metal containing nanocomposites on the kinetics of microbial population development

Magnetic nanoparticles are promising nanomaterials for biomedical applications. Studies have been conducted to study the effect of iron-containing nanoparticles at concentrations of 1.0 and 10.0 maximum tolerated dose for total iron on the growth and development of the microbial population of E.coli. On the basis of the obtained results, it was found that nanoparticles affect the growth characteristics of E.coli, related to human gram-negative prokaryotic microflora. The level of biological activity of nanoparticles depends on their concentration. © Published under licence by IOP Publishing Ltd.Russian Science Foundation, RSF: 18-19-00090In part this research was funded by the Russian Science Foundation, grant number 18-19-00090