Effective Actions for the SU(2) Confinement-Deconfinement Phase Transition

We compare different Polyakov loop actions yielding effective descriptions of finite-temperature SU(2) Yang-Mills theory on the lattice. The actions are motivated by a simultaneous strong-coupling and character expansion obeying center symmetry and include both Ising and Ginzburg-Landau type models. To keep things simple we limit ourselves to nearest-neighbor interactions. Some truncations involving the most relevant characters are studied within a novel mean-field approximation. Using inverse Monte-Carlo techniques based on exact geometrical Schwinger-Dyson equations we determine the effective couplings of the Polyakov loop actions. Monte-Carlo simulations of these actions reveal that the mean-field analysis is a fairly good guide to the physics involved. Our Polyakov loop actions reproduce standard Yang-Mills observables well up to limitations due to the nearest-neighbor approximation.Comment: 14 pages, 10 figures, v2: typos correcte

Robust single-parameter quantized charge pumping

This paper investigates a scheme for quantized charge pumping based on single-parameter modulation. The device was realized in an AlGaAs-GaAs gated nanowire. We find a remarkable robustness of the quantized regime against variations in the driving signal, which increases with applied rf power. This feature together with its simple configuration makes this device a potential module for a scalable source of quantized current.Comment: Submitted to Appl. Phys. Let

Artificial neural networks for 3D cell shape recognition from confocal images

We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood disease. Characteristic shape features are revealed from the spherical harmonics spectrum of each cell and are automatically processed to create a reproducible and unbiased shape recognition and classification for diagnostic and theragnostic use.Comment: 17 pages, 8 figure

Single-parameter non-adiabatic quantized charge pumping

Controlled charge pumping in an AlGaAs/GaAs gated nanowire by single-parameter modulation is studied experimentally and theoretically. Transfer of integral multiples of the elementary charge per modulation cycle is clearly demonstrated. A simple theoretical model shows that such a quantized current can be generated via loading and unloading of a dynamic quasi-bound state. It demonstrates that non-adiabatic blockade of unwanted tunnel events can obliterate the requirement of having at least two phase-shifted periodic signals to realize quantized pumping. The simple configuration without multiple pumping signals might find wide application in metrological experiments and quantum electronics.Comment: 4 pages, 4 figure

Quantitative Neutron Dark-field Imaging through Spin-Echo Interferometry

Neutron dark field imaging constitutes a seminal progress in the field of neutron imaging as it combines real space resolution capability with information provided by one of the most significant neutron scattering techniques, namely small angle scattering. The success of structural characterizations bridging the gap between macroscopic and microscopic features has been enabled by the introduction of grating interferometers so far. The induced interference pattern, a spatial beam modulation, allows for mapping of small angle scattering signals and hence addressing microstructures beyond direct spatial resolution of the imaging system with high efficiency. However, to date the quantification in the small angle scattering regime is severely limited by the monochromatic approach. To overcome such drawback we here introduce an alternative and more flexible method of interferometric beam modulation utilizing a spin echo technique. This novel method facilitates straightforward quantitative dark field neutron imaging, i.e. the required quantitative microstructural characterization combined with real space image resolution. For the first time quantitative microstructural reciprocal space information from small angle neutron scattering becomes available together with macroscopic image information creating the potential to quantify several orders of magnitude in structure sizes simultaneousl

Energy-time entanglement of quasi-particles in solid-state devices

We present a proposal for the experimental observation of energy-time entanglement of quasi-particles in mesoscopic physics. This type of entanglement arises whenever correlated particles are produced at the same time and this time is uncertain in the sense of quantum uncertainty, as has been largely used in photonics. We discuss its feasibility for electron-hole pairs. In particular, we argue that the recently fabricated 2DEG-2DHG junctions, irradiated with a continuous laser, behave as "entanglers" for energy-time entanglement.Comment: 4 pages, 3 figure

Distribution of moisture in reconstructed oil paintings on canvas during absorption and drying: a neutron radiography and NMR study

Moisture is a driving factor in the long-term mechanical deterioration of canvas paintings, as well as for a number of physico–chemical degradation processes. Since the 1990s a number of publications have addressed the equilibrium hygroscopic uptake and the hygro-mechanical deformation of linen canvas, oil paint, animal glue, and ground paint. In order to visualise and quantify the dynamic behaviour of these materials combined in a painting mock-up or reconstruction, we have performed custom-designed experiments with neutron radiography and nuclear magnetic resonance (NMR) imaging. This paper reports how both techniques were used to obtain spatially and temporally resolved information on moisture content, during alternate exposure to high and low relative humidity, or in contact with liquids of varying water activities. We observed how the canvas, which is the dominant component in terms of volumetric moisture uptake, absorbs and dries rapidly, and, due to its low vapour resistance, allows for vapour transfer towards the ground layer. Moisture desorption was generally found to be faster than absorption. The presence of sizing glue leads to a local increase of moisture content. It was observed that lining a painting with an extra canvas results in a damping effect: i.e. absorption and drying are significantly slowed down. The results obtained by NMR are complementary to neutron radiography in that they allow accurate monitoring of water ingress in contact with a liquid reservoir. Quantitative results are in good agreement with adsorption isotherms. The findings can be used for risk analysis of paintings exposed to changing micro-climates or subjected to conservation treatments using water. Future studies addressing moisture-driven deformation of paintings can make use of the proposed experimental techniques

Changes in Blood Cell Deformability in Chorea-Acanthocytosis and Effects of Treatment With Dasatinib or Lithium

Misshaped red blood cells (RBCs), characterized by thorn-like protrusions known as acanthocytes, are a key diagnostic feature in Chorea-Acanthocytosis (ChAc), a rare neurodegenerative disorder. The altered RBC morphology likely influences their biomechanical properties which are crucial for the cells to pass the microvasculature. Here, we investigated blood cell deformability of five ChAc patients compared to healthy controls during up to 1-year individual off-label treatment with the tyrosine kinase inhibitor dasatinib or several weeks with lithium. Measurements with two microfluidic techniques allowed us to assess RBC deformability under different shear stresses. Furthermore, we characterized leukocyte stiffness at high shear stresses. The results showed that blood cell deformability–including both RBCs and leukocytes - in general was altered in ChAc patients compared to healthy donors. Therefore, this study shows for the first time an impairment of leukocyte properties in ChAc. During treatment with dasatinib or lithium, we observed alterations in RBC deformability and a stiffness increase for leukocytes. The hematological phenotype of ChAc patients hinted at a reorganization of the cytoskeleton in blood cells which partly explains the altered mechanical properties observed here. These findings highlight the need for a systematic assessment of the contribution of impaired blood cell mechanics to the clinical manifestation of ChAc