Sustainable development of territories based on the integrated use of industry, resource and environmental potential

Purpose: Attention to the problems of social and economic development of rural areas by Government authorities, economists and the scientific community was mainly theoretical or sometimes targeted practical in nature. Design/Methodology/Approach: At the same time, rural poverty and high unemployment rate, worsening demographic situation, reducing network of institutions of social infrastructure in rural areas, which together have a negative impact on the reproduction of labor resources, lower production volumes and high migration rates have always been the problems of rural development in the country. Findings: Overall, sustainable development of rural areas characterizes, on the one hand, external major natural resource constraints that form a distant prospect, and on the other hand, determine the possibilities of social and economic development of rural communities, economic entities, diversification of the territory's economy, the formation of new activities and environmental engineering. This is a very wide range of problems, which are currently considered from different perspectives in Russia and in several countries of the world. Practical implications: The article discusses the problems of economic development of rural areas as the main factor in ensuring the sustainable development of rural areas of the agrarian regions of Russia. Originality/Value: The authors define the core resources for development of the rural areas in the region, provide an overview of agribusiness and tourism industry clusters, reveling their points of growth, cluster sales channels, tourism and recreation development.peer-reviewe

Organizational and economic transformations towards the greening of agro-industrial production

The increase in the production of agricultural products and food supplies in excess of regulatory needs and the provision of food safety in Russia led to the expansion of the export of agricultural products and the change in the course of the development of the agro-industrial complex from import substitution to export-oriented production. However, the entry to world food markets requires high quality of products from manufacturers and its certification in accordance with world standards. The article presents the organizational and economic transformations towards the greening of agro-industrial production, namely, the use of the resource potential, the involvement of Russian manufacturers in the production of environmentally friendly products and the development of organic agriculture; the mechanisms for solving the set problems are substantiated.peer-reviewe

Formation of zonal agro-eco clusters as a mechanism for the development of rural areas

Today, the degree of agricultural development, and, in the future, the level of national food security, the public health and the quality of life, are largely ensured by innovative developments in the field of alternative agriculture, the preservation of natural resources and, above all, the main production facility – land. At the same time, the unfilled market capacity of organic products and the significant land potential for the development of organic farming create all the necessary prerequisites for enhancing the competitiveness of Russian rural producers. The development of agricultural entrepreneurship towards the greening of land use, organic production and development of the domestic market for organic (ecological) products in the format of zonal agro-eco clusters is one of the strategic directions for implementing reforms in the agricultural sector. The paper presents the directions of the formation and development of zonal agro-eco clusters for the production, processing and sale of organic products in the agricultural regions of Russia.peer-reviewe

Comparative Analysis of Clinical, Hormonal and Morphological Studies in Patients with Neuroendocrine ACTH-Producing Tumours

This paper highlights the problem of neuroendocrine tumours (NETs) with clinical symptoms of hypercorticism caused by hypersecretion of adrenocorticotropic hormone (ACTH) by tumour cells. In most cases (85%), the tumours were localized in the pituitary gland (Cushing's disease); 15% of the patients had an extrapituitary tumour that manifest as an ectopic ACTH secretion (EAS). Comparative analysis of clinical, hormonal, histological, and immunohistochemical characteristics of pituitary and extrapituitary ACTH-secreting NET was performed. It included 46 patients with CD and 38 ones exhibiting ectopic ACTH secretion (EAS). Results of the study suggest differences between CD and EAS in terms of the severity of clinical manifestations and duration of the disease. Hormonal studies showed that EAS unlike CD was associated with high plasma ACTH and cortisol levels, late-evening salivary cortisol and daily urinary free cortisol, the absence of a 60% or greater reduction of cortisol in the HDDST test, and the presence of a low (less than 2) ACTH gradient in response to desmopressin administration with catheterization of cavernous sinuses. The study of morphofunctional characteristics of the removed NET demonstrated the ability of both pituitary and extrapituitary NETs to express ACTH as well as GH, PRL, LH, and FSH. The angiogenic markers (CD31 and VEGF) were detected with equal frequency regardless of the NET localization. The histological structure of all corticotropinomas suggested their benign origin, but extrapituitary NETs were represented by different morphological types with varying malignancy, invasiveness, and metastatic properties. A higher cell proliferation potential (Ki-67) was documented for NET in patients presenting with an ectopic ACTH secretion compared to those having corticotropinomas

Ecological and economic potential and prospects for organic production in the regions of Russia

Purpose: The article assesses the ecological and economic potential of organic production in the regions of Russia and substantiates the prospects for the regions’ production activity. Design: Assessment of the resource potential of the Russian regions in the direction of the development of organic agriculture, the substantiation of the effectiveness of new areas of activity for the Russian agrarian economy. Findings: The increase in agricultural and food production in excess of regulatory needs in order to ensure food security in Russia has led to the expansion of agricultural exports as well as to a change of the agro-industrial complex development vector from import substitution to export-oriented production. Practical implications: Environmental problems of agriculture are identified, mechanisms for their solution are justified. Based on the environmental and economic assessment, the most promising agrarian regions were selected as potential producers of organic products. Originality: The article substantiates ecological, economic and resource potential, shows the potential of the producers of the Russian regions in the production of organic products, the development of organic agriculture and the use of bio-intensive agricultural technologies.peer-reviewe

Ensuring the national security of agriculture in the digital era through the formation of human capital

Purpose: Over the past few years in many literary sources and the media an issue of the digital economy is rapidly gaining popularity due to the qualitative technological changes in society. In current circumstances the qualitative component of labor resources called “human capital” is a priority value. Design/Methodology/Approach: The following research methods have been used in the work: monographic, abstract-logical, sociological, economic-mathematical and calculation-constructive ones. Findings: The solution of the problem of ensuring food security of the population of the region depends on the methods and strategies of applying technologies in domestic and global agriculture, as well as on the correct and effective use of scientific-technical implementations in the industry. Practical implications: Identification of segments in tourism is mainly made based on their geographical, demographical, socio-economic, psychographic, behavior characteristics or their combinations. On the other hand, the authors stress on the fact that there is no universal segmentation approach and therefore, potential tourists can be classified based on other characteristics. Originality/Value: The use of digital technologies in the agricultural industry will increase the efficiency of production activities.peer-reviewe

Formation of human capital as a key factor in ensuring the national security of agriculture in the digital economy

Over the past few years in many literary sources and the media an issue of the digital economy is rapidly gaining popularity due to the qualitative technological changes in society. In current circumstances the qualitative component of labor resources called “human capital” is a priority value. The authors have identified the main realities of the development of agribusiness, studied the main directions of information support on the example of the agricultural sector of the economy and identified the root causes of the slowdown in the innovation development of agriculture in Russia, the features of using information technologies in agribusiness have been considered in detail.peer-reviewe

Directions to improve economic efficiency of regional production

The paper provides theoretical grounding and the directions for improving the economic efficiency of the regional feedstuff production. The study develops a conceptual model of distributing management functions of feedstuff production between the regional authorities of state sectoral and economic management and the district level. The authors suggest the methodology for calculating potential capacity of intraregional feedstuff market, considering the demands of all categories of agricultural manufacturers. The study examines possibilities for implementing the strategy of diversified growth and development of the intraregional feedstuff market, including the terms of interaction between the large and micro-business inside the industry and cooperation of micro-business feedstuff manufacturers with agricultural production. The authors have developed the methodology for assessing the efficiency of feedstuff production, based on the aggregate estimation of the management organization, conditions for the development of feedstuff production and changes in the feedstuff production and livestock breeding industry.peer-reviewe

Development of human capital in the system of economic categories of work

Today, human capital is one of the main factors in the formation of the knowledge economy, which is the highest stage in the development of an innovative, post-industrial economy. The development of intellectual and spiritual capabilities of a person, as well as the accumulation of human capital, which has a strong influence on the productivity and quality of labor, becomes one of the priorities for the future development of the state. This article discusses the development of human capital in the system of economic categories of labor.peer-reviewe