Bounds on Cubic Lorentz-Violating Terms in the Fermionic Dispersion Relation

We study the recently proposed Lorentz-violating dispersion relation for fermions and show that it leads to two distinct cubic operators in the momentum. We compute the leading order terms that modify the non-relativistic equations of motion and use experimental results for the hyperfine transition in the ground state of the ${}^9\textrm Be^+$ ion to bound the values of the Lorentz-violating parameters $\eta_1$ and $\eta_2$ for neutrons. The resulting bounds depend on the value of the Lorenz-violating background four-vector in the laboratory frame.Comment: Revtex 4, four pages. Version to match the one to appear in Physical Review

Formation of cosmological mass condensation within a FRW universe: exact general relativistic solutions

Within the framework of an exact general relativistic formulation of gluing manifolds, we consider the problem of matching an inhomogeneous overdense region to a Friedmann-Robertson-Walker background universe in the general spherical symmetric case of pressure-free models. It is shown that, in general, the matching is only possible through a thin shell, a fact ignored in the literature. In addition to this, in subhorizon cases where the matching is possible, an intermediate underdense region will necessarily arise.Comment: 6 page

Pharmacogenetics of analgesic drugs

• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. • While pharmacokinetic properties of drugs, metabolism in particular, have been scrutinised by genotype–phenotype correlation studies, the clinical significance of inherited variants in genes governing pharmacodynamics of analgesics remains largely unexplored (apart from the µ-opioid receptor). • Lack of replication of the findings from one study to another makes meaningful personalised analgesic regime still a distant future. • This narrative review will focus on findings related to pharmacogenetics of commonly used analgesic medications and highlight authors’ views on future clinical implications of pharmacogenetics in the context of pharmacological treatment of chronic pain

Cosmic Acceleration from M Theory on Twisted Spaces

In a recent paper [I.P. Neupane and D.L. Wiltshire, Phys. Lett. B 619, 201 (2005).] we have found a new class of accelerating cosmologies arising from a time--dependent compactification of classical supergravity on product spaces that include one or more geometric twists along with non-trivial curved internal spaces. With such effects, a scalar potential can have a local minimum with positive vacuum energy. The existence of such a minimum generically predicts a period of accelerated expansion in the four-dimensional Einstein-conformal frame. Here we extend our knowledge of these cosmological solutions by presenting new examples and discuss the properties of the solutions in a more general setting. We also relate the known (asymptotic) solutions for multi-scalar fields with exponential potentials to the accelerating solutions arising from simple (or twisted) product spaces for internal manifolds.Comment: 23 pages, 3 figures; added a summary Table, PRD versio

Four-spin-exchange- and magnetic-field-induced chiral order in two-leg spin ladders

We propose a mechanism of a vector chiral long-range order in two-leg spin-1/2 and spin-1 antiferromagnetic ladders with four-spin exchanges and a Zeeman term. It is known that for one-dimensional quantum systems, spontaneous breakdown of continuous symmetries is generally forbidden. Any vector chiral order hence does not appear in spin-rotationally [SU(2)]-symmetric spin ladders. However, if a magnetic field is added along the S^z axis of ladders and the SU(2) symmetry is reduced to the U(1) one, the z component of a vector chiral order can emerge with the remaining U(1) symmetry unbroken. Making use of Abelian bosonization techniques, we actually show that a certain type of four-spin exchange can yield a vector chiral long-range order in spin-1/2 and spin-1 ladders under a magnetic field. In the chiral-ordered phase, the Z_2 interchain-parity (i.e., chain-exchange) symmetry is spontaneously broken. We also consider effects of perturbations breaking the parity symmetry.Comment: 8 pages, 1 figure, RevTex, published versio

Topological Discrete Algebra, Ground State Degeneracy, and Quark Confinement in QCD

Based on the permutation group formalism, we present a discrete symmetry algebra in QCD. The discrete algebra is hidden symmetry in QCD, which is manifest only on a space-manifold with non-trivial topology. Quark confinement in the presence of the dynamical quarks is discussed in terms of the discrete symmetry algebra. It is shown that the quark deconfinement phase has the ground state degeneracy depending on the topology of the space, which gives a gauge-invariant distinction between the confinement and deconfinement phases. We also point out that new quantum numbers relating to the fractional quantum Hall effect exist in the deconfinement phase.Comment: 11 pages, 1 figur

Extraction of P11 resonances from pi N data

We show that two P11 nucleon resonance poles near the pi Delta threshold, obtained in several analyses, are stable against large variations of parameters within a dynamical coupled-channels analysis based on meson-exchange mechanisms. By also performing an analysis based on a model with a bare nucleon state, we find that this two-pole structure is insensitive to the analytic structure of the amplitude in the region below pi N threshold. Our results are M_pole = (1363^{+9}_{-6} -i79^{+3}_{-5}) MeV and (1373^{+12}_{-10} -i114^{+14}_{-9}) MeV. We also demonstrate that the number of poles in the 1.5 GeV < W < 2 GeV region could be more than one, depending on how the structure of the single-energy solution of SAID is fitted. For three-pole solutions, our best estimated result of a pole near N(1710) listed by Particle Data Group is (1829^{+131}_{-65} -i192^{+88}_{-110}) MeV which is close to the results of several previous analyses. Our results indicate the need of more accurate pi N reaction data in the W > 1.6 GeV region for high precision resonance extractions.Comment: 15 pages, 4 figure

Chandra deep X-ray observation on the Galactic plane

Using the Chandra ACIS-I instruments, we have carried out the deepest X-ray observation on a typical Galactic plane region at l 28.5 deg, where no discrete X-ray sources have been known previously. We have detected, as well as strong diffuse emission, 275 new point X-ray sources (4 sigma confidence) within two partially overlapping fields (~250 arcmin^2 in total) down to ~3 x 10^{-15} erg s^{-1} cm^{-2} (2 -- 10 keV) or ~ 7 x 10^{-16} erg s^{-1} cm^{-2} (0.5 -- 2 keV). We have studied spectral distribution of these point sources, and found that very soft sources detected only below ~ 3 keV are more numerous than hard sources detected only above ~ 3 keV. Only small number of sources are detected both in the soft and hard bands. Surface density of the hard sources is almost consistent with that at high Galactic regions, thus most of the hard sources are considered to be Active Galactic Nuclei seen through the milky way. On the other hand, some of the bright hard X-ray sources which show extremely flat spectra and iron line or edge features are considered to be Galactic, presumably quiescent dwarf novae. The soft sources show thermal spectra and small interstellar hydrogen column densities, and some of them exhibit X-ray flares. Therefore, most of the soft sources are probably X-ray active nearby late type stars.Comment: Contribution to the proceedings of the "New Visions of the X-Ray Universe in the XMM-Newton and Chandra Era" symposium at ESTEC, The Netherlands. 26-30 Nov. 200