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    ЭпидСмиологичСская характСристика папилломавирусной ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½ΠΎΠΉ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ Π² РСспубликС Ватарстан

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    Due to the high prevalence of anogenital warts, their significant economic and psychosocial burden, the lack of routine vaccination against papillomavirus infection, monitoring of the epidemiological situation for one of the common forms of papillomavirus infection – anogenital warts is relevant.The aim is to assess the epidemiological situation of anogenital warts in Tatarstan Republic for 2011–2020.Materials and methods. The study design is an observational descriptive epidemiological study. A retrospective epidemiological analysis of the incidence of anogenital warts in Tatarstan Republic for 2011–2020 was carried out. The analysis of long-term dynamics of incidence of the population as a whole and in age and sex groups is carried out. The structure of the incidence of anogenital warts was assessed. Intensive (per 100,000) and extensive morbidity rates (%) were calculated.Results. There is a decrease in the incidence of anogenital warts in Republic Tatarstan from 123,80/0000 in 2011 to 68,80/0000 in 2020. The dynamics of the incidence of anogenital warts among the female and male population had a unidirectional character – a decrease in the incidence. A comparison of incidence levels showed that the incidence of women was higher than that of men (80,40/0000 versus 55,80/0000, respectively, in 2020). The greatest incidence of anogenital warts was observed in the 18–29 age group during the observation period. The average annual incidence of anogenital warts in women aged 18–29 was 535,60/0000, in men of the same age group – 233,00/0000.Conclusion. Despite the decrease in the incidence of anogenital warts in Tatarstan Republic as a whole and in certain age and gender groups, high levels of incidence among people aged 18-29 years remain. The data obtained from the results of a retrospective analysis of the incidence of anogenital warts indicate the need to introduce routine vaccination against HPV infection, which will prevent large treatment costs, and will have a positive impact on public health indicators.Π’ силу высокой распространСнности Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹Ρ… Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΎΠΊ, ΠΈΡ… сущСствСнного экономичСского ΠΈ ΠΏΡΠΈΡ…ΠΎΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ Π±Ρ€Π΅ΠΌΠ΅Π½ΠΈ, отсутствия ΠΏΠ»Π°Π½ΠΎΠ²ΠΎΠΉ Π²Π°ΠΊΡ†ΠΈΠ½Π°Ρ†ΠΈΠΈ ΠΏΡ€ΠΎΡ‚ΠΈΠ² папилломавирусной ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ прСдставляСтся Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΌΠΎΠ½ΠΈΡ‚ΠΎΡ€ΠΈΠ½Π³Π° эпидСмиологичСской ситуации Π·Π° ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· распространСнных Ρ„ΠΎΡ€ΠΌ папилломавирусной ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ – Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ.ЦСль: ΡƒΡΡ‚Π°Π½ΠΎΠ²ΠΈΡ‚ΡŒ закономСрности проявлСний эпидСмичСского процСсса Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹Ρ… Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΎΠΊ Π² РСспубликС Ватарстан Π·Π° ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ с 2011 ΠΏΠΎ 2020 Π³.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Π”ΠΈΠ·Π°ΠΉΠ½ исслСдования – обсСрвационноС ΠΎΠΏΠΈΡΠ°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ эпидСмиологичСскоС исслСдованиС. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ рСтроспСктивный эпидСмиологичСский Π°Π½Π°Π»ΠΈΠ· заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ Π² РСспубликС Ватарстан Π·Π° 2011–2020 Π³Π³. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅Ρ‚Π½Π΅ΠΉ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ заболСваСмости насСлСния Π² Ρ†Π΅Π»ΠΎΠΌ ΠΈ Π² возрастных ΠΈ ΠΏΠΎΠ»ΠΎΠ²Ρ‹Ρ… Π³Ρ€ΡƒΠΏΠΏΠ°Ρ…. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π° ΠΎΡ†Π΅Π½ΠΊΠ° структуры заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ. Рассчитаны интСнсивныС (Π½Π° 100 000) ΠΈ экстСнсивныС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ заболСваСмости (%).Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. ΠžΡ‚ΠΌΠ΅Ρ‡Π°Π΅Ρ‚ΡΡ сниТСниС заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ Π² РСспубликС Ватарстан с 123,80/0000 Π² 2011 Π³. Π΄ΠΎ 68,80/0000 Π² 2020 Π³. Π”ΠΈΠ½Π°ΠΌΠΈΠΊΠ° Π³ΠΎΠ΄ΠΎΠ²Ρ‹Ρ… ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ срСди ТСнского ΠΈ муТского насСлСния ΠΈΠΌΠ΅Π»Π° ΠΎΠ΄Π½ΠΎΠ½Π°ΠΏΡ€Π°Π²Π»Π΅Π½Π½Ρ‹ΠΉ Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ – сниТСниС заболСваСмости. ΠŸΡ€ΠΈ сравнСнии интСнсивных ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡ‚ΡŒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Π±Ρ‹Π»Π° Π²Ρ‹ΡˆΠ΅ заболСваСмости ΠΌΡƒΠΆΡ‡ΠΈΠ½ (80,40/0000 ΠΏΡ€ΠΎΡ‚ΠΈΠ² 55,8 0/0000 соотвСтствСнно, ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ 2020 Π³.). НаибольшиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°ΡŽΡ‚ΡΡ Π² Π³Ρ€ΡƒΠΏΠΏΠ΅ 18–29 Π»Π΅Ρ‚ Π² Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ всСго ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π° наблюдСния. Π‘Ρ€Π΅Π΄Π½Π΅ΠΌΠ½ΠΎΠ³ΠΎΠ»Π΅Ρ‚Π½ΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΡŒ заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ 18–29 Π»Π΅Ρ‚ составил 535,60/0000, ΠΌΡƒΠΆΡ‡ΠΈΠ½ Ρ‚ΠΎΠΉ ΠΆΠ΅ возрастной Π³Ρ€ΡƒΠΏΠΏΡ‹ – 233,00/0000.Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. НСсмотря Π½Π° сниТСниС заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ, Π² РСспубликС Ватарстан Π² Ρ†Π΅Π»ΠΎΠΌ ΠΈ Π² ΠΎΡ‚Π΄Π΅Π»ΡŒΠ½Ρ‹Ρ… половозрастных Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… ΡΠΎΡ…Ρ€Π°Π½ΡΡŽΡ‚ΡΡ высокиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ заболСваСмости срСди Π»ΠΈΡ† 18–29 Π»Π΅Ρ‚. Π”Π°Π½Π½Ρ‹Π΅, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ ΠΏΠΎ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π°ΠΌ рСтроспСктивного Π°Π½Π°Π»ΠΈΠ·Π° заболСваСмости Π°Π½ΠΎΠ³Π΅Π½ΠΈΡ‚Π°Π»ΡŒΠ½Ρ‹ΠΌΠΈ Π±ΠΎΡ€ΠΎΠ΄Π°Π²ΠΊΠ°ΠΌΠΈ, ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΡŽΡ‚ ΠΎ нСобходимости внСдрСния ΠΏΠ»Π°Π½ΠΎΠ²ΠΎΠΉ Π²Π°ΠΊΡ†ΠΈΠ½Π°Ρ†ΠΈΠΈ ΠΏΡ€ΠΎΡ‚ΠΈΠ² Π’ΠŸΠ§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ (Ρ‡Π΅Ρ‚Ρ‹Ρ€Π΅Ρ…Π²Π°Π»Π΅Π½Ρ‚Π½ΠΎΠΉ Π²Π°ΠΊΡ†ΠΈΠ½ΠΎΠΉ), Ρ‡Ρ‚ΠΎ ΠΏΡ€Π΅Π΄ΠΎΡ‚Π²Ρ€Π°Ρ‚ΠΈΡ‚ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ большиС Π·Π°Ρ‚Ρ€Π°Ρ‚Ρ‹ Π½Π° Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅, Π½ΠΎ ΠΈ ΠΎΠΊΠ°ΠΆΠ΅Ρ‚ ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ влияниС Π½Π° ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ общСствСнного Π·Π΄ΠΎΡ€ΠΎΠ²ΡŒΡ

    Modern prevention strategies of HIV infection (review of literature)

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    Despite preventive measures, the problem of HIV infection in the Russian Federation remains important. The goal of prevention programs is to prevent the spread of HIV infection among the population. There are three levels of prevention. Primary prevention is aimed at the general population and is to minimize exposure to risk factors. It includes testing of donated blood for HIV, prevention of drug and alcohol abuse, education and training to promote safe sex, safe injection practices, circumcision, and the use of microbicides. Secondary prevention aims at early diagnosis for the disease and counselling of infected persons to prevent infecting others. Tertiary prevention aims to prevent disease progression and development of complications, and includes treatment, rehabilitation and social support for people living with HIV. Measures of tertiary prevention are partly fulfilling the role of primary preventive measures. Therefore, a high level of patients' adherence to antiretroviral therapy can significantly reduce the risk of transmitting the virus to their sexual partners due to the suppression of viral replication and therefore help reduce the spread of the disease among the population. In different subpopulations and regions, the importance of factors influencing epidemic process differs. Prevention programs should take into account the characteristics of the epidemic in each region. The review analyzes various directions, strategies and programs of HIV prevention, which are effective among the population

    Epidemiological Features of Sexually Transmitted Infections in the Republic of Tatarstan

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    Relevance. Sexually transmitted infections (STIs) remain an urgent problem in modern society due to the high incidence of morbidity, the development of complications, including cancer, affecting the reproductive health of the population. The purpose of the study is to assess the incidence of sexually transmitted infections in the Republic of Tatarstan, including the incidence of certain nosoforms (syphilis, gonorrhea, trichomoniasis, chlamydial infection anogenital warts and urogenital herpes) in the period 2013–2017. Material and methods. A descriptive epidemiological study was conducted-a retrospective analysis of the incidence of STIs in the Republic of Tatarstan. We analyzed the long-term dynamics of the overall incidence of STIs, as well as for the nosoforms of STIs for the period from 2013 to 2017. The data was processed using Microsoft Excel 2010 and OpenEpi online calculators. Results. There is a statistically significant downward trend in the overall incidence of STIs in Russia, RT, and Kazan in 2013–2017 (p < 0.05). The incidence ofΒ STIs is higher in Kazan and the Republic of Tatarstan in comparison with the incidence of the population of the Russian Federation. A statistically significant decrease in the incidence of syphilis, gonorrhea, trichomoniasis, chlamydia, and anogenital warts was detected in 2013–2017 (p < 0.05). Among the nosologies of STIs, anogenital warts have the highest incidence rates (84.8 cases per 100 ths) and occupy the 1st place in the structure of STIs in the Republic of Tatarstan (53.3% in 2017). Conclusion. The long-term dynamics of morbidity is characterized by a statistically significant downward trend in the overall incidence of STIs in the Republic of Tatarstan in 2013–2017. Anogenital warts dominate the structure of STI in the Republic of Tatarstan

    Π”Π˜ΠΠΠœΠ˜ΠšΠ ΠŸΠ ΠžΠ―Π’Π›Π•ΠΠ˜Π™ Π­ΠŸΠ˜Π”Π•ΠœΠ˜Π§Π•Π‘ΠšΠžΠ“Πž ΠŸΠ ΠžΠ¦Π•Π‘Π‘Π Π’Π˜Π§-Π˜ΠΠ€Π•ΠšΠ¦Π˜Π˜ Π’Πž Π’Π—ΠΠ˜ΠœΠžΠ‘Π’Π―Π—Π˜ Π‘ Π­ΠŸΠ˜Π”Π•ΠœΠ˜ΠžΠ›ΠžΠ“Π˜Π§Π•Π‘ΠšΠžΠ™ Π‘Π˜Π’Π£ΠΠ¦Π˜Π•Π™ ПО НАРКОМАНИИ (ПО ΠœΠΠ’Π•Π Π˜ΠΠ›ΠΠœ Π Π•Π‘ΠŸΠ£Π‘Π›Π˜ΠšΠ˜ ВАВАРБВАН)

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    The aim of the study is to characterize the trends in the development of the epidemic process of HIV infection in connection with the epidemiological situation of drug addiction in the Republic of Tatarstan.Materials and methods. The official statistical data on the incidence of HIV infection and drug addiction in the Republic of Tatarstan for the period 1987–2016, the data on the prevalence for 2001 and 2016 are analyzed.Results. Direct correlation of the prevalence of HIV infection and prevalence of drug addiction in the different territories of the Republic of Tatarstan were identified for 2001 data (r=0,81, p&lt;0,001) and for 2016 (r=0,82, p&lt;0,001). A statistically significant increase in the incidence of HIV infection in the population against the background of a decrease in the incidence of drug addiction was demonstrated. In the early stages of the epidemic in the region HIV infection spread mainly through injecting drug use and, in recent years, HIV has been sexually transmitted mainly through heterosexual contact.Conclusion. The output of infection outside the population of injecting drug users and the prevalence of sexual transmission of HIV in recent yearsare a reflection of adverse trends in the direction of generalization of the epidemic of HIV infection.ЦСль исслСдования: Π΄Π°Ρ‚ΡŒ характСристику Ρ‚Π΅Π½Π΄Π΅Π½Ρ†ΠΈΠΉ развития эпидСмичСского процСсса Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ Π²ΠΎ взаимосвязи с эпидСмиологичСской ситуациСй ΠΏΠΎ Π½Π°Ρ€ΠΊΠΎΠΌΠ°Π½ΠΈΠΈ Π½Π° ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»ΠΎΠ² РСспублики Ватарстан.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ ΠΎΡ„ΠΈΡ†ΠΈΠ°Π»ΡŒΠ½Ρ‹Π΅ статистичСскиС Π΄Π°Π½Π½Ρ‹Π΅ ΠΏΠΎ заболСваСмости Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠ΅ΠΉ ΠΈ Π½Π°Ρ€ΠΊΠΎΠΌΠ°Π½ΠΈΠ΅ΠΉ Π² РСспубликС Ватарстан Π·Π° ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ с 1987 ΠΏΠΎ 2016 Π³ΠΎΠ΄, Π΄Π°Π½Π½Ρ‹Π΅ ΠΏΠΎ распространСнности Π·Π° 2001 ΠΈ 2016 Π³ΠΎΠ΄Ρ‹.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. ВыявлСна прямая связь ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ распространСнности Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ ΠΈ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ распространСнности Π½Π°Ρ€ΠΊΠΎΠΌΠ°Π½ΠΈΠΈ Π½Π° Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… тСрриториях РСспублики Ватарстан ΠΊΠ°ΠΊ для Π΄Π°Π½Π½Ρ‹Ρ… 2001 Π³ΠΎΠ΄Π° (r=0,81, p&lt;0,001), Ρ‚Π°ΠΊ ΠΈ для 2016 Π³ΠΎΠ΄Π° (r=0,82, p&lt;0,001). ΠŸΡ€ΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Π½ статистичСски Π·Π½Π°Ρ‡ΠΈΠΌΡ‹ΠΉ рост заболСваСмости насСлСния Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠ΅ΠΉ Π½Π° Ρ„ΠΎΠ½Π΅ сниТСния заболСваСмости Π½Π°Ρ€ΠΊΠΎΠΌΠ°Π½ΠΈΠ΅ΠΉ. На Π½Π°Ρ‡Π°Π»ΡŒΠ½Ρ‹Ρ… этапах развития эпидСмии Π² Ρ€Π΅Π³ΠΈΠΎΠ½Π΅ Π’Π˜Π§-инфСкция Ρ€Π°ΡΠΏΡ€ΠΎΡΡ‚Ρ€Π°Π½ΡΠ»Π°ΡΡŒ прСимущСствСнно ΠΏΡ€ΠΈ ΠΈΠ½ΡŠΠ΅ΠΊΡ†ΠΈΠΎΠ½Π½ΠΎΠΌ Π²Π²Π΅Π΄Π΅Π½ΠΈΠΈ Π½Π°Ρ€ΠΊΠΎΡ‚ΠΈΠΊΠΎΠ², Π° Π² послСдниС Π³ΠΎΠ΄Ρ‹ β€” ΠΏΠΎΠ»ΠΎΠ²Ρ‹ΠΌ ΠΏΡƒΡ‚Π΅ΠΌ, прСимущСствСнно ΠΏΡ€ΠΈ Π³Π΅Ρ‚Π΅Ρ€ΠΎΡΠ΅ΠΊΡΡƒΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΊΠΎΠ½Ρ‚Π°ΠΊΡ‚Π°Ρ….Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. Π’Ρ‹Ρ…ΠΎΠ΄ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ Π·Π° ΠΏΡ€Π΅Π΄Π΅Π»Ρ‹ популяции ΠΏΠΎΡ‚Ρ€Π΅Π±ΠΈΡ‚Π΅Π»Π΅ΠΉ ΠΈΠ½ΡŠΠ΅ΠΊΡ†ΠΈΠΎΠ½Π½Ρ‹Ρ… Π½Π°Ρ€ΠΊΠΎΡ‚ΠΈΠΊΠΎΠ² ΠΈ ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°Π½ΠΈΠ΅ Π² послСдниС Π³ΠΎΠ΄Ρ‹ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠ³ΠΎ ΠΏΡƒΡ‚ΠΈ зараТСния ΡΠ²Π»ΡΡŽΡ‚ΡΡ ΠΎΡ‚Ρ€Π°ΠΆΠ΅Π½ΠΈΠ΅ΠΌ нСблагоприятной Ρ‚Π΅Π½Π΄Π΅Π½Ρ†ΠΈΠΈ Π² Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠΈ Π³Π΅Π½Π΅Ρ€Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ эпидСмии Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ.</p
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