1,431 research outputs found

    Regge Trajectories of Tetraquarks and Pentaquarks with Massive Quarks in the Flux Tube Model

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    In recent years, many tetraquarks and pentaquarks have been discovered by various experimental groups and X(3872), Zc(3900), X(4430), P + c (4312), P + c (4457) are some of the interesting observed tetraquark and pentaquark states. The Regge trajectories of some such states are studied in view of the flux tube model of hadrons with finite quark masses. The effect of flux tube (or string) length variation on the Regge trajectories of these sates is analysed in detail. It is observed that for a fixed angular momentum, the string length has a constant value. Some other states are also proposed and the results obtained are then compared with the studies by others. Our findings correspond rather well with those of other researchers and with those of the experiment.Comment: 10 pages, 4 figures, Published in IJMP

    BUCCAL MUCOADHESIVE FILMS

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    The buccal route of administration has many advantages, including gastrointestinal bypass surgery and first pass through the liver. The mucoadhesive membrane is a retention dosage form that can release the drug directly into the biological matrix. Cheek technology has proven to be an advanced alternative to other traditional devices. The type of drug delivery system. This is a mature technology for systemic administration of active pharmaceutical ingredients [API]. In addition, due to their small size and thinness, these films improve patient compliance. Over the past decade, because it is a promising delivery alternative for multiple therapeutic categories, including peptides, vaccines and nanoparticles. Mucosal adhesions are currently explained by six theories: electronics, adsorption, wettability, diffusion, degradation and mechanics. Various in vitro and in vivo techniques are suggested. Study its mechanism. This study includes an overview of the mechanisms and theories of mucosal adhesion, and introduces the most commonly used methods. The "film casting method" involves casting an aqueous solution and/or organic solvent to produce a film suitable for the application route. The determination of key properties such as mucosal adhesion strength, uniformity of active ingredient content and permeability are important research areas in the field of buccal membrane design

    Marine fish landings in Andhra Pradesh during 2016 - An overview

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    Andhra Pradesh with a coastline of 974 km, and nine coastal districts has 1.63 lakh marine fishermen families residing in the 555 marine fishing villages (Marine Fisheries Census 2010) who depend on fishing either directly or through allied activities for their livelihood. The state is cyclone prone and during the past decade, cyclones have severely affected the state’s fisheries sector. The marine fish landings was 1.92 lakh tonnes (t) in the year 2016, which was 35% less than that of the previous year. The drastic reduction in the landings of the state may be attributed to reduction in fishing operations during the months of September, October and November due to cyclone warnings. Among the coastal districts, East Godavari contributed the highest (33%) to total marine fish landings of the state, followed by Visakhapatnam (22%) and Srikakulam (11%). In spite of decline in the catch contributions from a few landing centres like Bhairavpalem

    The health of women and girls determines the health and well-being of our modern world: A White Paper From the International Council on Women's Health Issues

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    The International Council on Women's Health Issues (ICOWHI) is an international nonprofit association dedicated to the goal of promoting health, health care, and well-being of women and girls throughout the world through participation, empowerment, advocacy, education, and research. We are a multidisciplinary network of women's health providers, planners, and advocates from all over the globe. We constitute an international professional and lay network of those committed to improving women and girl's health and quality of life. This document provides a description of our organization mission, vision, and commitment to improving the health and well-being of women and girls globally

    A putative heat-responsive transcription factor (TaHD97) and its targets in wheat (Triticum aestivum) providing thermotolerance

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    214-223Transcription factors (TFs) are protein, which perform their role at transcriptional level by affecting the expression of various genes associated with metabolic pathways, growth and stress-associated genes (SAGs) at different developmental stages. Here, we identified 38 novel heat-responsive transcription factor genes from wheat cv. HD2985 by mining the de novo transcriptome data derived from heat shock (HS) treated wheat. Based on digital gene expression (DGE), a putative transcript (TaHD97) of ~1.1 kbas amplified and cloned from wheat cv. HD2985. The presence of heat stress transcription factor (HSF) DNA binding domain was observed in the amino acid sequence. Differential expression of TaHD97 was observed in HD2985 (thermotolerant) and HD2329 (thermosensitive) under heat stress. Tissue specific expression analysis showed up-regulation of TaHD97 in leaves, stem and endospermic tissues and down-regulation in root under HS. A positive correlation was established between the expression of TaHD97 and its target gene (HSP17 and HSP90) in wheat under heat stress. HSP17 transcripts were observed more in leaves of HD2985, as compared to HD2329. Thermotolerance related biochemical enzymes (SOD, CAT, GPX and TBARS) were observed higher in wheat cv. HD2985 showing maximum expression of TaHD97 under heat stress. There is a need for the functional validation of the gene TaHD97 in order to use it for the regulation of sHSP (catalytic chaperone) - a novel approach towards augmenting thermotolerance in wheat under heat stress

    Population distribution analyses reveal a hierarchy of molecular players underlying parallel endocytic pathways.

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    Single-cell-resolved measurements reveal heterogeneous distributions of clathrin-dependent (CD) and -independent (CLIC/GEEC: CG) endocytic activity in Drosophila cell populations. dsRNA-mediated knockdown of core versus peripheral endocytic machinery induces strong changes in the mean, or subtle changes in the shapes of these distributions, respectively. By quantifying these subtle shape changes for 27 single-cell features which report on endocytic activity and cell morphology, we organize 1072 Drosophila genes into a tree-like hierarchy. We find that tree nodes contain gene sets enriched in functional classes and protein complexes, providing a portrait of core and peripheral control of CD and CG endocytosis. For 470 genes we obtain additional features from separate assays and classify them into early- or late-acting genes of the endocytic pathways. Detailed analyses of specific genes at intermediate levels of the tree suggest that Vacuolar ATPase and lysosomal genes involved in vacuolar biogenesis play an evolutionarily conserved role in CG endocytosis

    Overview of marine fisheries in India during 2007

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    Fisheries sector in India plays an important role in the country’s economy and it supports the livelihood of millions of people. India is having 8,129 km of coastal length with 2.02 million sq. km of Exclusive Economic Zone (upto 200 m depth) and 0.452 million sq. km of continental shelf area

    Productivity and profitability of drip fertigated wheat (Triticum aestivum) – mungbean (Vigna radiata) – maize (Zea mays) cropping system

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    An experiment was conducted at the research farm of ICAR-Indian Agricultural Research Institute, New Delhi during 2019–20 and 2020–21 to study the productivity and economic viability of wheat (Triticum aestivum L.)– mungbean (Vigna radiata (L.) R. Wilczek)–maize (Zea mays L.) fertigated with 0, 60, 80, 100% recommended doses of NPK and irrigated at 0.6 and 0.8 crop evapotranspiration (ETc) through subsurface (SSDI) and surface drip irrigation (SDI). The results were compared with the conventional practice of surface irrigation and soil application of 100% recommended doses of NPK. Grain yields of wheat, mungbean, maize and system wheat equivalent yield (SWEY) improved by 22.9, 7.2, 21.9 and 19.4%, respectively with increase in NPK fertigation doses from 60 to 100% and by 15.6, 9.2, 4.9 and 9.7% with the increase in irrigation frequency from 0.6 to 0.8 ETc. However, SDI and SSDI had equal system productivity (12.48 and 12.85 Mg/ha). The SWEY at 0.8ETc fertigated either with NPK80 or NPK100 was statistically at par (14.2–15.9 Mg/ha) with the conventional practice (14.3–15.2 Mg/ha). The cash inflow, net income and benefit cost ratio (BCR) of the cropping system also increased successively with increase in fertigation doses and irrigation frequency. The net income and BCR followed the order maize>wheat>mungbean. The net income under SSDI at 0.8 ETc with NPK80 or NPK100 in wheat, mungbean, maize and system was 11–13, 88–105, 1-9 and 8–14% higher than the conventional practice. At 0.8 ETc and NPK100, BCR in SSDI (1.86) was higher than in SDI (1.71) and conventional system (1.67).

    New quasar proximity zone size measurements at z6z\sim 6 using the enlarged XQR-30 sample

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    Proximity zones of high-redshift quasars are unique probes of their central supermassive black holes as well as the intergalactic medium in the last stages of reionization. We present 22 new measurements of proximity zones of quasars with redshifts between 5.8 and 6.6, using the enlarged XQR-30 sample of high-resolution, high-SNR quasar spectra. The quasars in our sample have UV magnitudes of M145027M_{1450}\sim -27 and black hole masses of 10910^9\unicode{x2013}101010^{10} M_\odot. Our inferred proximity zone sizes are 2\unicode{x2013}7 physical Mpc, with a typical uncertainty of less than 0.5 physical Mpc, which, for the first time, also includes uncertainty in the quasar continuum. We find that the correlation between proximity zone sizes and the quasar redshift, luminosity, or black hole mass, indicates a large diversity of quasar lifetimes. Two of our proximity zone sizes are exceptionally small. The spectrum of one of these quasars, with z=6.02z=6.02, displays, unusually for this redshift, damping wing absorption without any detectable metal lines, which could potentially originate from the IGM. The other quasar has a high-ionization absorber \sim0.5 pMpc from the edge of the proximity zone. This work increases the number of proximity zone measurements available in the last stages of cosmic reionization to 87. This data will lead to better constraints on quasar lifetimes and obscuration fractions at high redshift, which in turn will help probe the seed mass and formation redshift of supermassive black holes.Comment: 16 pages, 9 figures, Accepted in MNRA

    Genome Majority Vote Improves Gene Predictions

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    Recent studies have noted extensive inconsistencies in gene start sites among orthologous genes in related microbial genomes. Here we provide the first documented evidence that imposing gene start consistency improves the accuracy of gene start-site prediction. We applied an algorithm using a genome majority vote (GMV) scheme to increase the consistency of gene starts among orthologs. We used a set of validated Escherichia coli genes as a standard to quantify accuracy. Results showed that the GMV algorithm can correct hundreds of gene prediction errors in sets of five or ten genomes while introducing few errors. Using a conservative calculation, we project that GMV would resolve many inconsistencies and errors in publicly available microbial gene maps. Our simple and logical solution provides a notable advance toward accurate gene maps
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