Non relativistic Broad Band wake fields and potential-well distortion

The study of the interaction between a particle beam and wake fields is usually based on the assumption of ultra relativistic beams. This is not the case, for example, for the Proton Synchrotron Booster(PSB), in which protons cover the energy range. There are some examples in literature which derive nonultra relativistic formulae for the resistive wall impedance. In this paper we have extended the Broad-Band resonator model, allowing the impedance to have poles even in the upper half complex plane, in order to obtain a wake function different from zero for. The Haissinski equation has been numerically solved showing longitudinal bunch shape changes with. In addition some longitudinal bunch profile measurements, taken for two different bunch intensities at the PSB, are shown

Structure retrieval at atomic resolution in the presence of multiple scattering of the electron probe

The projected electrostatic potential of a thick crystal is reconstructed at atomic-resolution from experimental scanning transmission electron microscopy data recorded using a new generation fast- readout electron camera. This practical and deterministic inversion of the equations encapsulating multiple scattering that were written down by Bethe in 1928 removes the restriction of established methods to ultrathin ($\lesssim 50$ {\AA}) samples. Instruments already coming on-line can overcome the remaining resolution-limiting effects in this method due to finite probe-forming aperture size, spatial incoherence and residual lens aberrations.Comment: 6 pages, 3 figure

Community Libraries in England: Empowering Volunteers and a catalyst for change

This paper explores the balance between austerity localism (a reaction to public budget cuts) and progressive localism (a challenge to neo-liberalist hegemony) in the transfer of libraries to volunteer management. It is based on interviews in libraries in a northern city. Libraries in the U.K. are vulnerable to budget cuts as the extent of statutory provision is ambiguous and transfer to volunteer management may be the only viable alternative to closure. Volunteers felt compelled to act to save their libraries from closure, but in doing so were developing new services and ways of providing them. This showed a nuanced balance between a reaction to austerity and an approach which could be regarded as ‘progressive’. The paper contributes to the meaning and use of the concept of ‘progressive localism’, and understanding the synergy between this and ‘austerity localism’ within the asset transfer of library services

Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease

Background: Hyperphosphataemia is linked to cardiovascular disease and mortality in chronic kidney disease (CKD). Outcome in CKD is also affected by socioeconomic status. The objective of this study was to assess the associations between serum phosphate, multiple deprivation and outcome in CKD patients. Methods: All adult patients currently not on renal replacement therapy (RRT), with first time attendance to the renal outpatient clinics in the Glasgow area between July 2010 and June 2014, were included in this prospective study. Area socioeconomic status was assessed as quintiles of the Scottish Index of Multiple Deprivation (SIMD). Outcomes were all-cause and cardiovascular mortality and commencement of RRT. Results: The cohort included 2950 patients with a median (interquartile range) age 67.6 (53.6–76.9) years. Median (interquartile range) eGFR was 38.1 (26.3–63.5) ml/min/1.73 m 2 , mean (±standard deviation) phosphate was 1.13 (±0.24) mmol/L and 31.6 % belonged to the most deprived quintile (SIMD quintile I). During follow-up 375 patients died and 98 commenced RRT. Phosphate ≥1.50 mmol/L was associated with all-cause (hazard ratio (HR) 2.51; 95 % confidence interval (CI) 1.63-3.89) and cardiovascular (HR 5.05; 95 % CI 1.90–13.46) mortality when compared to phosphate 0.90–1.09 mmol/L in multivariable analyses. SIMD quintile I was independently associated with all-cause mortality. Phosphate did not weaken the association between deprivation index and mortality, and there was no interaction between phosphate and SIMD quintiles. Neither phosphate nor SIMD predicted commencement of RRT. Conclusions Multiple deprivation and serum phosphate were strong, independent predictors of all-cause mortality in CKD and showed no interaction. Phosphate also predicted cardiovascular mortality. The results suggest that phosphate lowering should be pursued regardless of socioeconomic status

Coherent tune shift and instabilities measurements at the CERN Proton Synchrotron Booster

To understand one of the contributions to the intensity limitations of the CERN Proton Synchrotron Booster (PSB) in view of its operation with beams from Linac 4, the impedance of the machine has been characterized. Measurements of tune shift as a function of the intensity have been carried out in order to estimate the low frequency imaginary part of the impedance. Since the PSB is a low energy machine, these measurements have been done at two different energies, so as to enable us to disentangle the effect of the indirect space charge and resistive wall from the contribution of the machine impedance. An estimation of the possible resonant peaks in the impedance spectrum has been made by measuring a fast instability in Ring4

Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients

Background and purpose: End stage renal disease (ESRD) requiring hemodialysis (HD) carries up to a 10-fold greater risk of stroke than normal renal function. Knowledge concerning risk factors and management strategies derived from the general population may not be applicable to those with ESRD. We studied a large ESRD population to identify risk factors and outcomes for stroke. Methods: All adult patients receiving HD for ESRD from 01/01/2007 to 31/12/2012 were extracted from the electronic patient record. Variables associated with stroke were identified by survival analysis; demographic, clinical, imaging and dialysis related variables were assessed and case-fatality determined. Follow-up was until 31/12/2013. Results: 1382 patients were identified (mean age 60.5 years, 58.5% male). The prevalence of AF was 21.2% and 59.4% were incident HD patients. 160 (11.6%) experienced a stroke during 3471 patient-years of follow-up (95% ischemic). Stroke incidence was 41.5/1000 patient-years in prevalent and 50.1/1000 patient-years in incident HD patients. Factors associated with stroke on regression analysis were prior stroke, diabetes and age at starting renal replacement therapy. AF was not significantly associated with stroke and warfarin did not affect stroke risk in warfarin treated patients. Fatality was 18.8% at 7, 26.9% at 28 and 56.3% 365 days after stroke.<p></p> Conclusions: Incidence of stroke is high in patients with ESRD on HD with high case-fatality. Incident HD patients had the highest stroke incidence. Many, but not all, important risk factors commonly associated with stroke in the general population were not associated with stroke in patients receiving HD

Shine 2014 Final Report: Social Prescribing: integrating GP and Community Assets for Health

Commissioned by City and Hackney Clinical Commissioning Group, in partnership with the University of East London and Queen Mary University of London