602 research outputs found

    NEPA at 21: Over the Hill Already?

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    The first part of this Comment will briefly review the somewhat meteoric rise of NEPA including the increase in public awareness which led to federal action, its projected effect, and the manner in which the courts seemed to be heading in their treatment of NEPA. The Comment will then review the decline of NEPA due to subsequent Supreme Court decisions. Finally, the Comment will consider possible remedies for the present anemic condition of this first federal environmental statute

    Artificial Insemination of Dairy Cattle.

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    Artificial Insemination of Dairy Cattle.

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    5p

    Similarity in cognitive complexity and attraction to friends and lovers: Experimental and correlational studies

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    Abstract OnlyTwo studies are reported examining whether similarities in cognitive complexity foster different forms of interpersonal attraction. Study 1 provided an experimental test of the hypothesis that perceivers would be more attracted to targets with similar levels of complexity than to targets with dissimilar levels of complexity. Participants read interpersonal impressions reflecting low and high levels of cognitive complexity and completed 3 assessments of attraction (social, task, and intellectual) to the source of the impressions. As predicted, there were significant interactions between perceiver complexity and target complexity such that high-complexity perceivers were more attracted to high-complexity targets than were low-complexity perceivers, whereas low-complexity perceivers were more attracted to low-complexity targets than were high-complexity perceivers. Unexpectedly, however, low-complexity perceivers were more attracted to a high-complexity target than a low-complexity target. Study 2 examined the effects of similarities in cognitive complexity on attraction among 126 pairs of dating partners. Partners having similar levels of cognitive complexity expressed significantly greater intellectual attraction to one another than partners having dissimilar levels of cognitive complexity

    Inclusive pion double charge exchange on O-16 above the delta resonance

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    The forward inclusive pion double charge exchange reaction, ^{16}O(pi^-,pi^+)X, at T_0 = 0.50 and 0.75 GeV has been studied in the kinematical region where an additional pion production is forbidden by energy-momentum conservation. The experiment was performed with the SKS spectrometer at KEK PS. The measured ratio of double charge exchange cross-section for these energies dsigma(0.50 GeV)/dOmega / dsigma(0.75 GeV)/dOmega = 1.7 +/- 0.2, disagrees with the value of 7.2 predicted within the conventional sequential single charge exchange mechanism. Possible reasons for the disagreement are discussed in connection with the Glauber inelastic rescatterings.Comment: 4 pages, 5 figure

    Charge Form Factor and Cluster Structure of 6^6Li Nucleus

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    The charge form factor of 6{}^6Li nucleus is considered on the basis of its cluster structure. The charge density of 6{}^6Li is presented as a superposition of two terms. One of them is a folded density and the second one is a sum of 4{}^4He and the deuteron densities. Using the available experimental data for 4{}^4He and deuteron charge form factors, a good agreement of the calculations within the suggested scheme is obtained with the experimental data for the charge form factor of 6{}^6Li, including those in the region of large transferred momenta.Comment: 12 pages 5 figure

    Pion-nucleus elastic scattering on 12C, 40Ca, 90Zr, and 208Pb at 400 and 500 MeV

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    Pion-nucleus elastic scattering at energies above the Delta(1232) resonance is studied using both pi+ and pi- beams on 12C, 40Ca, 90Zr, and 208Pb. The present data provide an opportunity to study the interaction of pions with nuclei at energies where second-order corrections to impulse approximation calculations should be small. The results are compared with other data sets at similar energies, and with four different first-order impulse approximation calculations. Significant disagreement exists between the calculations and the data from this experiment

    MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma

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    Purpose This study assessed whether Myristoylated Alanine Rich C-Kinase Substrate (MARCKS) can regulate glioblastoma (GBM) growth, radiation sensitivity and clinical outcome. Experimental Design MARCKS protein levels were analyzed in five GBM explant cell lines and eight patient-derived xenograft tumors by immunoblot, and these levels were correlated to proliferation rates and intracranial growth rates, respectively. Manipulation of MARCKS protein levels was assessed by lentiviral-mediated shRNA knockdown in the U251 cell line and MARCKS over-expression in the U87 cell line. The effect of manipulation of MARCKS on proliferation, radiation sensitivity and senescence was assessed. MARCKS gene expression was correlated with survival outcomes in the Repository of Molecular Brain Neoplasia Data (REMBRANDT) Database and The Cancer Genome Atlas (TCGA). Results MARCKS protein expression was inversely correlated with GBM proliferation and intracranial xenograft growth rates. Genetic silencing of MARCKS promoted GBM proliferation and radiation resistance, while MARCKS overexpression greatly reduced GBM growth potential and induced senescence. We found MARCKS gene expression to be directly correlated with survival in both the REMBRANDT and TCGA databases. Specifically, patients with high MARCKS expressing tumors of the Proneural molecular subtype had significantly increased survival rates. This effect was most pronounced in tumors with unmethylated O6-methylguanine DNA methyltransferase (MGMT) promoters, a traditionally poor prognostic factor. Conclusions MARCKS levels impact GBM growth and radiation sensitivity. High MARCKS expressing GBM tumors are associated with improved survival, particularly with unmethylated MGMT promoters. These findings suggest the use of MARCKS as a novel target and biomarker for prognosis in the Proneural subtype of GBM
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