Discovery of Temperate Latitude Clouds on Titan

Until now, all the clouds imaged in Titan's troposphere have been found at far southern latitudes (60°-90° south). The occurrence and location of these clouds is thought to be the result of convection driven by the maximum annual solar heating of Titan's surface, which occurs at summer solstice (2002 October) in this south polar region. We report the first observations of a new recurring type of tropospheric cloud feature, confined narrowly to ~40° south latitude, which cannot be explained by this simple insolation hypothesis. We propose two classes of formation scenario, one linked to surface geography and the other to seasonally evolving circulation, which will be easily distinguished with continued observations over the next few years

Titan imagery with Keck adaptive optics during and after probe entry

We present adaptive optics data from the Keck telescope, taken while the Huygens probe descended through Titan's atmosphere and on the days following touchdown. No probe entry signal was detected. Our observations span a solar phase angle range from 0.05° up to 0.8°, with the Sun in the west. Contrary to expectations, the east side of Titan's stratosphere was usually brightest. Compiling images obtained with Keck and Gemini over the past few years reveals that the east-west asymmetry can be explained by a combination of the solar phase angle effect and an enhancement in the haze density on Titan's morning hemisphere. While stratospheric haze was prominent over the northern hemisphere, tropospheric haze dominated the south, from the south pole up to latitudes of ∼45°S. At 2.1 μm this haze forms a polar cap, while at 1.22 μm it appears in the form of a collar at 60°S. A few small clouds were usually present near the south pole, at altitudes of 30–40 km. Our narrowband J,H,K images of Titan's surface compare extremely well with that obtained by Cassini ISS, down to the small-scale features. The surface contrast between dark and bright areas may be larger at 2 μm than at 1.6 and 1.3 μm, which would imply that the dark areas may be covered by a coarser-grained frost than the bright regions and/or that there is additional 2 μm absorption there

A new 1.6-micron map of Titan’s surface

We present a new map of Titan's surface obtained in the spectral 'window' at ∼1.6 μm between strong methane absorption. This pre-Cassini view of Titan's surface was created from images obtained using adaptive optics on the W.M. Keck II telescope and is the highest resolution map yet made of Titan's surface. Numerous surface features down to the limits of the spatial resolution (∼200–300 km) are apparent. No features are easily identifiable in terms of their geologic origin, although several are likely craters

Functional Microbial Features Driving Community Assembly During Seed Germination and Emergence

Microbial interactions occurring on and around seeds are especially important for plant fitness since seed-borne microorganisms are the initial source of inoculum for the plant microbiota. In this study, we analyze structural and functional changes occurring within the plant microbiota at these early stages of the plant cycle, namely germination and emergence. To this purpose, we performed shotgun DNA sequencing of microbial assemblages associated to seeds, germinating seeds and seedlings of two plant species: bean and radish. We observed an enrichment of and during emergence and a set of functional traits linked to copiotrophy that could be responsible for this selection as a result of an increase of nutrient availability after germination. Representative bacterial isolates of taxa that are selected in seedlings showed indeed faster bacterial growth rate in comparison to seed-associated bacteria isolates. Finally, binning of metagenomics contigs results in the reconstruction of population genomes of the major bacterial taxa associated to the samples. Together, our results demonstrate that, although seed microbiota varied across plant species, nutrient availability during germination elicits changes of the composition of microbial communities by potentially selecting microbial groups with functional traits linked to copiotrophy. The data presented here represents the first attempts to empirically assess changes in the microbial community during plant emergence and moves us toward a more holistic understanding of the plant microbiome

Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use

Levosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart failure (HF). In the ensuing 20 years, this distinctive inodilator, which enhances cardiac contractility through calcium sensitization and promotes vasodilatation through the opening of adenosine triphosphate-dependent potassium channels on vascular smooth muscle cells, has been approved in more than 60 jurisdictions, including most of the countries of the European Union and Latin America. Areas of clinical application have expanded considerably and now include cardiogenic shock, takotsubo cardiomyopathy, advanced HF, right ventricular failure, pulmonary hypertension, cardiac surgery, critical care, and emergency medicine. Levosimendan is currently in active clinical evaluation in the United States. Levosimendan in IV formulation is being used as a research tool in the exploration of a wide range of cardiac and noncardiac disease states. A levosimendan oral form is at present under evaluation in the management of amyotrophic lateral sclerosis. To mark the 20 years since the advent of levosimendan in clinical use, 51 experts from 23 European countries (Austria, Belgium, Croatia, Cyprus, Czech Republic, Estonia, Finland, France, Germany, Greece, Hungary, Italy, the Netherlands, Norway, Poland, Portugal, Russia, Slovenia, Spain, Sweden, Switzerland, the United Kingdom, and Ukraine) contributed to this essay, which evaluates one of the relatively few drugs to have been successfully introduced into the acute HF arena in recent times and charts a possible development trajectory for the next 20 years

Optical characterization of the PALM-3000 3388-actuator deformable mirror

We describe the lab characterization of the new 3,388-actuator deformable mirror (DM3388) produced by Xinetics, Inc. for the PALM-3000 adaptive optics (AO) system1 under development by Jet Propulsion Laboratory and Caltech Optical Observatories. This square grid 66-by-66 actuator mirror has the largest number of actuators of any deformable mirror currently available and will enable high-contrast imaging for direct exoplanet imaging science at the Palomar 200" diameter Hale Telescope. We present optical measurements of the powered and unpowered mirror surface, influence functions, linearity of the actuators, and creep of the actuators. We also quantify the effect of changes in humidity

Geographic Control of Titan's Mid-Latitude Clouds

Observations of Titan's mid-latitude clouds from the W. M. Keck and Gemini Observatories show that they cluster near 350°W longitude, 40°S latitude. These clouds cannot be explained by a seasonal shift in global circulation and thus presumably reflect a mechanism on Titan such as geysering or cryovolcanism in this region. The rate of volatile release necessary to trigger cloud formation could easily supply enough methane to balance the loss to photolysis in the upper atmosphere

Adaptive optics imaging of a stellar occultation by Titan

We present resolved images of the occultation of a binary star by Titan, recorded with the Palomar Observatory adaptive optics system on 20 December 2001 UT. These constitute the first resolved observations of a stellar occultation by a small body, and demonstrate several unique capabilities of diffraction-limited imaging systems for the study of planetary atmospheres. Two refracted stellar images are visible on Titan's limb throughout both events, displaying scintillations due to local density variations. Precise relative astrometry of the refracted stellar images with respect to the unnocculted component of the binary allows us to directly measure their altitude in Titan's atmosphere. Their changing positions also lead to simple demonstration of the finite oblateness of surfaces of constant pressure in Titan's mid-latitude stratosphere, consistent with the only previous measurement of Titan's zonal wind field