22 research outputs found
Optico-physical technologies of diagnostics of the biological activity of gydroxyl-containing aromatic compounds
Optico-physical technologies of diagnostics of the biological activity of gydroxyl-containing aromatic compounds
Manifestation of structure and intermolecular interactions of biologically active brassinosteroids in infrared spectra
Spectral-luminescent and proton-acceptor properties of biologically active hydroxyl-substituted benzaldehydes
Spectral-luminescent and proton-acceptor properties of biologically active hydroxyl-substituted benzaldehydes
Quantum-Chemical Study of the Influence of Substitution on Anti-Virus Activity of Hydroxyl Substituted Benzaldehydes and Related Compounds
IR Fourier–Spectroscopy and Pharmacological Properties of Phenols
IR Fourier spectra of pharmacologically active phenol molecules in solutions and crystals in CCl4 are studied. The analysis of the screened phenols has shown that phenols with free hydroxyl groups possess the most antimicrobial activity. The manifestation of antiviral activity of aminophenols is associated with forming intramolecular hydrogen bonds in solutions. Phenyl-containing aminophenols, which have high activity against herpes virus, are characterized by the formation of the O-H...N-type intramolecular hydrogen bond. The main sign of high activity of aminophenols against group A virus is the predominance of the O-H...O=C-type intramolecular hydrogen bond. Sulfur-containing aminophenols, which show their activity against HIV-infection, have hydrogen bonds with O-H-, N-H- and SO2 -groups in solutions and crystals
IR Fourier–Spectroscopy and Pharmacological Properties of Phenols
IR Fourier spectra of pharmacologically active phenol molecules in solutions and crystals in CCl4 are studied. The analysis of the screened phenols has shown that phenols with free hydroxyl groups possess the most antimicrobial activity. The manifestation of antiviral activity of aminophenols is associated with forming intramolecular hydrogen bonds in solutions. Phenyl-containing aminophenols, which have high activity against herpes virus, are characterized by the formation of the O-H...N-type intramolecular hydrogen bond. The main sign of high activity of aminophenols against group A virus is the predominance of the O-H...O=C-type intramolecular hydrogen bond. Sulfur-containing aminophenols, which show their activity against HIV-infection, have hydrogen bonds with O-H-, N-H- and SO2 -groups in solutions and crystals