5,119 research outputs found
Finished goods inventory control and warehousing of a knit goods company
Thesis (M.B.A.)--Boston Universit
Far eastern markets
Thesis (M.B.A.)--Boston University
PLEASE NOTE: page 115 appears to be missing from the thesis. Our determination is that this is the result of misnumbering by the author, and no substantive content is actually missing. If you are able to determine otherwise, please contact us
Effect of PRRSV Infection on MHC Expression by Macrophages and Monocytes
Porcine reproductive and respiratory syndrome virus (PRRSV) is a recent and widespread pathogen in the U.S. swine population. PRRSV infects cells of the macrophage/ monocyte/dendritic lineages which are important antigen presenting cells (APCs) of the immune system. Using flow cytometric (FACs) analysis, we demonstrated that PRRSV infection decreases the expression of the major histocompatibility complex (MHC) glycoproteins on the cell surface of infected macrophages. This decrease in MHC protein expression may reduce the ability of the macrophages to present viral antigens to the appropriate lymphocytes. The potential lack of viral antigen presentation may play a crucial role in the persistent viremia observed in PRRSV-infected pigs
Quark-Antiquark Forces From SU(2) and SU(3) Gauge Theories on Large Lattices
We present results on the spin-independent quark-antiquark potential in SU(3)
gauge theory from a simulation on a 48^3*64 lattice at Beta = 6.8,
corresponding to a volume of (1.7 fm)^3. Moreover, a comprehensive analysis of
spin- and velocity-dependent potentials is carried out for SU(2) gauge theory,
with emphasis on the short range structure, on lattices with resolutions
ranging from .02 fm to .04 fm.Comment: 10 pages, uucompressed latex with 5 ps figures, epsf style require
Toward an Improved Analytical Description of Lagrangian Bias
We carry out a detailed numerical investigation of the spatial correlation
function of the initial positions of cosmological dark matter halos. In this
Lagrangian coordinate system, which is especially useful for analytic studies
of cosmological feedback, we are able to construct cross-correlation functions
of objects with varying masses and formation redshifts and compare them with a
variety of analytical approaches. For the case in which both formation
redshifts are equal, we find good agreement between our numerical results and
the bivariate model of Scannapieco & Barkana (2002; SB02) at all masses,
redshifts, and separations, while the model of Porciani et al. (1998) does well
for all parameters except for objects with different masses at small
separations. We find that the standard mapping between Lagrangian and Eulerian
bias performs well for rare objects at all separations, but fails if the
objects are highly-nonlinear (low-sigma) peaks. In the Lagrangian case in which
the formation redshifts differ, the SB02 model does well for all separations
and combinations of masses, apart from a discrepancy at small separations in
situations in which the smaller object is formed earlier and the difference
between redshifts or masses is large. As this same limitation arises in the
standard approach to the single-point progenitor distribution developed by
Lacey & Cole (1993), we conclude that a more complete understanding of the
progenitor distribution is the most important outstanding issue in the analytic
modeling of Lagrangian bias.Comment: 22 pages, 8 figures, ApJ, in pres
The flux distribution of the three quark system in SU(3)
We study the abelian color-flux distribution of the three quark system in the
maximally abelian gauge on SU(3) lattices. The distribution of the color
electric field suggests , which might be interpreted through the dual
superconductor picture as the result of the vacuum pressure in the confined
phase. In order to clarify the flux structure, we investigate the color
electric field in the three quark system also in the monopole part and in the
photon part.Comment: 3pages, 5figures, Lattice2002(topology
EXPLORING LIPID-BASED DRUG DELIVERY IN CANCER THERAPY VIA LIPOSOMAL FORMULATIONS
In many countries across the world, cancer is a leading cause of death. Cancer is the biggest cause of death worldwide, with approximately 10 million fatalities expected in 2020, accounting for nearly one in every six deaths. Mutations in ~300 human genes can unleash cell division, potentially leading to cancer. The effectiveness of existing conventional therapies for a number of cancers is, however, inefficient in terms of safety and efficacy. Medication systems based on lipid can be configured to treat tumors passively with increasing safety by reducing toxicity and increasing efficacy by target drug delivery. Lipid-based drug dosage form is the new identified technological design to overcome problems such as water-soluble solubility and bioavailability. A wide range of product specifications determined by indication of disease, route of administration, price evaluation, safety, toxicity, and efficiency could be customized to lipid formulations. This analysis explores the current state of lipid drug delivery studies, including the production of cancer liposomes, different cancer-focused strategies, and liposomal formulation of numerous anti-cancer drugs
Orthopedic management of the extremities in patients with Morquio A syndrome.
BackgroundMusculoskeletal involvement in Morquio A syndrome (mucopolysaccharidosis IVA; MPS IVA) contributes significantly to morbidity and mortality. While the spinal manifestations of the disorder have received considerable attention in the literature, there have been few reported studies to date to guide the management of the orthopedic problems associated with the lower and upper extremities.PurposeThe objective was to develop recommendations for the management of the extremities in patients with Morquio A syndrome.MethodsA group of specialists in orthopedics, pediatrics and genetics with experience in the management of Morquio A patients convened to review and discuss current clinical practices and to develop preliminary recommendations. Evidence from the literature was retrieved. Recommendations were further refined until consensus was reached.Results and conclusionsThis present article provides a detailed review and discussion of the lower and upper extremity deformities in Morquio A syndrome and presents recommendations for the assessment and treatment of these complications. Key issues, including the importance of early diagnosis and the implications of medical therapy, are also addressed. The recommendations herein represent an attempt to develop a uniform and practical approach to managing patients with Morquio A syndrome and improving their outcomes
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