Performance of re-ranking techniques used for recommendation method to the user CF- Model

The recent research work for addressed to the aims at a spectrum of item ranking techniques that would generate recommendations with far more aggregate variability across all users while retaining comparable levels of recommendation accuracy. Individual users and companies are increasingly relying on recommender systems to provide information on individual suggestions. The recommended technologies are becoming increasingly efficient because they are focusing on scalable sorting-based heuristics that make decisions based solely on "local" data (i.e., only on the candidate items of each user) rather than having to keep track of "national" data, such as items have been all user recommended at the time. The real-world rating datasets and various assessments to be the prediction techniques and comprehensive empirical research consistently demonstrate the proposed techniques' diversity gains. Although the suggested approaches have primarily concentrated on improving recommendation accuracy, other critical aspects of recommendation quality, such as recommendation delivery, have often been ignored

Tribological and corrosion behaviors of warm- and hot-rolled Ti-13Nb-13Zr alloys in simulated body fluid conditions

Development of submicrocrystalline structure in biomedical alloy such as Ti-13Nb-13Zr (in wt%) through warm-rolling process has been found to enhance mechanical properties compared to conventional thermomechanical processing routes including hot-rolling process. The present study investigated the tribological and corrosion behaviors of warm-rolled (WR) and hot-rolled Ti-13Nb-13Zr alloys which have not been studied to date. Both tribological and corrosion experiments were carried out in simulated body fluid conditions (Hank's solution at 37 degrees C) based on the fact that the investigated alloys would be used in a human body as orthopedic implants. The WR Ti-13Nb-13Zr demonstrated a submicrocrystalline structure that provided a significant enhancement in hardness, strength, and corrosion resistance. Meanwhile, there was no notable difference in wear resistance between the WR and hot-rolled samples despite the different microstructure and hardness. The present study confirmed the enormous potential of WR Ti-13Nb-13Zr with not only great mechanical properties but also high corrosion resistance in the simulated body fluid.111Ysciescopu

Bumper catch of oil sardine Sardinella longiceps along Cuddalore coast

The oil sardine Sardinella longiceps constitutes the most important pelagic resource sustaining the marine fishery on the west coast of India. Two decades ago, the occurrence of this species along the east coast was considered sporadic and rare. In early eighties, there was report on the unusual landing of this species along Puducherry region. Over the years, there has been an increase in the landings of this species on the east coast especially along the Coromandal coast. In July 2008, there were reports in the local daily news papers that the oil sardine shoals were found to move towards the shore off Devanampattinam fishing village and small boys were also able to have easy access to the fish shoal who handpicked the sardines. Some fishes were also stranded and found dead on the beach. This occurrence is linked to upwelling phenomenon which brings the oxygen depleted cold water from the bottom of the sea due to churning by the water current

The Potential of Magnesium Alloys as Bioabsorbable/ Biodegradable Implants for Biomedical Applications

The potential of magnesium alloys as bioabsorbable / biodegradable implants for biomedical applications has been extensively studied as emerging direction. This paper gives a review of current topics in this field. Research activities related to biomedical magnesium alloys have been pursued in two main directions, orthopedic and cardiovascular implants, by investigating different aspects of alloying system design, novel structures, degradation rate control, and surface modification methods. Magnesium alloys are currently considered for applications as load-bearing implant devices such as plates, screws and pins for repairing bone fracture. Highly important direction of research is degradable coronary stents. Degradable vessel stents promote stable vessel regeneration, unlike permanent stents. Different combinations of alloying elements have been investigated in order to decrease corrosion rate.Tribological issues are also important for understanding of different phenomenon related to prolongation of Mg alloys corrosion degradation time/rate, such as tribocorrosion, corrosion fatigue, and fatigue crack growth behavior

Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis

Advances in the field of cancer immunology, including studies on tumor-infiltrating CD8(+) cytotoxic T lymphocytes (CTLs), have led to new immunotherapeutics with proven efficacy against late-stage cancers. However, the antitumor potential of the immune system in targeting early-stage cancers remains uncertain. Here, we demonstrated that both genetic and chemical induction of thymic stromal lymphopoietin (TSLP) at a distant site leads to robust antitumor immunity against spontaneous breast carcinogenesis in mice. Breast tumors exposed to high circulating levels of TSLP were arrested at an early adenoma-like stage and were prevented from advancing to late carcinoma and metastasis. Additionally, CD4(+) Th2 cells mediated the antitumor effects of TSLP, challenging the notion that Th2 cells only promote cancer. We also discovered that TSLP is expressed by the breast tumor cells themselves and acts to block breast cancer promotion. Moreover, TSLP-induced immunity also blocked early stages of pancreatic cancer development. Together, our findings demonstrate that TSLP potently induces immunity directed against early stages of breast cancer development without causing inflammation in the normal breast tissue. Moreover, our results highlight a previously unappreciated function of the immune system in controlling the early development of cancer and establish a fundamental role for TSLP and Th2 cells in tumor immunity against early-stage cancers

Biodegradable Mg and Mg based alloys for biomedical implants

Mg and its alloys become natural biomaterials as the elemental Mg is found in the human body in abundance and their mechanical properties being akin to the natural bone as well as due to their inherent bioabsorbable/bioresorbable property. This paper discusses the development of new Mg alloys and their corrosion characteristics in detail. The latest advancements in coating of Mg alloys to control their degradation rate are also reviewed along with the future challenges that need to be addressed

Summary of the National Conference on Challenges in Biomaterials Research jointly organized by VIT and CSIR-CECRI

Geetha Manivasagam,1 Balasubramanian Subramanian,2 Thomas J Webster3,4 1Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, Vellore Institute of Technology, Vellore, India; 2Electrochemical Materials Science Division, CSIR-Central Electrochemical Research Institute, Karaikudi, Tamil Nadu, India; 3Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 4Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi ArabiaHealth care has become one of the highest priority research fields of this century owing to the dramatic increase in the number of people affected by various diseases. Health care costs and the high demand for biomaterials have placed tremendous pressure on government funding agencies and researchers to develop cost-effective, appropriate biomaterials to treat various diseases and to regenerate diseased and fractured organs. The field of biomaterials is projected to generate approximately $80 billion by the end of this decade. Thus, various funding organizations have allocated considerable funding for the development of the next generation of biomaterials. Despite the fact that certain global regions and countries (such as the US, Europe, Australia, Brazil, and the People’s Republic of China) have considerable expertise in the manufacturing of various biomaterials, India has developed considerable expertise in specifically manufacturing cardiovascular and orthopedic implants over the past 3 decades