Occurrence of Native Copper Near Jefferson City, Montana

Sometime prior to 1870, a group of prospectors made what was believed to be a rich strike\u27 on one of the tributaries of Prickly Pear Creek in Jefferson County, Montana. Instead of striking it rich, they had uncovered a native copper deposit, worthless to them because of its limited extent and remote location, but now of much interest to the geologist, and to the mining engineer because of its possible commercial value

Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors.

Transforming growth factor beta-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes. We have sequenced TGFB1 regulatory region and assigned allelic genotypes in a large cohort of hematopoietic stem cell transplantation patients and donors. In this study, we analyzed 522 unrelated donor-patient pairs and examined the combined effect of all the common polymorphisms in this genomic region. In univariate analysis, we found that patients carrying a specific allele, 'p001', showed significantly reduced overall survival (5-year overall survival 30.7% for p001/ p001 patients vs. 41.6% others; P=0.032) and increased non-relapse mortality (1-year nonrelapse mortality: 39.0% vs. 25.4%; P=0.039) after transplantation. In multivariate analysis, the presence of a p001/ p001 genotype in patients was confirmed as an independent factor for reduced overall survival [hazard ratio=1.53 (1.04-2.24); P=0.031], and increased non-relapse mortality [hazard ratio=1.73 (1.06-2.83); P=0.030]. In functional experiments we found a trend towards a higher percentage of surface transforming growth factor beta-1-positive regulatory T cells after activation when the cells had a p001 allele (P=0.07). Higher or lower production of transforming growth factor beta-1 in the inflammatory context of hematopoietic stem cell transplantation may influence the development of complications in these patients. Findings indicate that TGFB1 genotype could potentially be of use as a prognostic factor in hematopoietic stem cell transplantation risk assessment algorithms

FIRST REPORT ON DINOSAUR TRACKS FROM THE BURRO CAN YON FORMATION, SAN JUAN COUNTY, UTAH, USA – EVIDENCE OF A DIVERSE, HITHERTO UN KNOWN LOWER CRETACEOUS DINOSAUR FAUNA

The newly discovered White Mesa tracksite in the Burro Canyon Formation represents a snap shot of a diverse, Lower Cretaceous dinosaur fauna from south-eastern Utah. The tracks were found at a construction site where the sand stone had been bull dozed and broken up. All tracks were found as deep, well-preserved natural casts on the under side of the sand stone slabs. Individual theropod tracks are 19–57 cm in length; one peculiar track shows evidence of a possible pathological swelling in the middle of digit III and an apparently didactyl track is tentatively as signed to a dromaeosaurid. Individual sauropod tracks are found with pes lengths of 36–72 cm, and interestingly, three distinct shapes of manus tracks, ranging from wide banana shaped to rounded and hoof-like. Ornithopods are represented with individual tracks 18–37 cm in length; a single track can possibly be attributed to the thyreophoran ichnogenus Deltapodus. Zircon U-Pb dating places the track-bearing layer in the Barremian, contemporary to the lower Yellow Cat Member of the Cedar Mountain Formation, which has a similar faunal composition based on both tracks and body fossils. This new track-fauna demonstrates the existence of a diverse dinosaurian assemblage in the lower part of the Burro Canyon Formation, which hitherto is not known to yield skeletal remains

Inappropriate Antidiuresis: Examples of an Hyponatremic Syndrome Resembling Exogenous Vasopressin Administration in Man

We have reviewed some of the features of hyponatremic syndromes, unassociated with sodium retention and edema, but associated with primary water retention. The syndromes were probably caused by excessive vasopressin activity, in the presence of normal circulatory, renal and adreno-cortical function. Underlying diseases, including bronchogenic carcinoma, head injury, and tuberculous meningitis, illustrated the diverse etiologic bases of this condition

Number-Theoretic Nature of Communication in Quantum Spin Systems

The last decade has witnessed substantial interest in protocols for transferring information on networks of quantum mechanical objects. A variety of control methods and network topologies have been proposed, on the basis that transfer with perfect fidelity --- i.e. deterministic and without information loss --- is impossible through unmodulated spin chains with more than a few particles. Solving the original problem formulated by Bose [Phys. Rev. Lett. 91, 207901 (2003)], we determine the exact number of qubits in unmodulated chains (with XY Hamiltonian) that permit the transfer with fidelity arbitrarily close to 1, a phenomenon called pretty good state transfer. We prove that this happens if and only if the number of nodes is n=p-1, 2p-1, where p is a prime, or n=2^{m}-1. The result highlights the potential of quantum spin system dynamics for reinterpreting questions about the arithmetic structure of integers, and, in this case, primality.Comment: 6 pages, 1 EPS figur